An improved method of transducing retinal ganglion cells using AAV via transpupillary injection in adult mouse eyes
Fangyu Lin, Su-Ting Lin, Jiaxing Wang, Jana T. Sellers, Micah A. Chrenek, John M. Nickerson, Jeffrey H. Boatright, Eldon E. Geisert
Published: 12 January 2025 [Full Text]
Serum pro-brain natriuretic peptide correlates with optical coherence tomography indices in diabetic retinopathy
Shivani Chaturvedi, Sandeep Saxena, Apjit Kaur, Pramod Kumar, Shivani Pandey, Abbas Ali Mahdi, Levent Akduman
Published: 18 January 2025 [Full Text]
Subclinical parents assist in the detection of genetic variants in keratoconus by trio-based whole-exome sequencing
Xingyong Li, Yinghao Yao, Shilai Xing, Siwen Ma, Shuaiyue Pang, Yang Zhou, Shihao Chen
Published: 17 February 2025 [Full Text]
Identification of genetic factors underlying severe retinopathy of prematurity in preterm infants
Huiqing Sun, Zhiyi Xia, Mingchao Li, Zengyuan Yu, Zhangsheng Wang, Shan Xing, Ping Cheng, Hongbo Zhang, Lifeng Li
Published: 01 March 2025 [Full Text]
Genetics and phenotypes of RPE65 mutations in inherited retinal degeneration: A study from a tertiary eye care center in Brazil
Sarah Pereira de Freitas Cenachi, Maria Frasson, Virgínia Mares, Rodrigo Rezende Arantes, Anna Luiza Braga Albuquerque, Anna Laura Marques Nascentes, Luiz Armando Cunha De Marco, Márcio Bittar Nehemy
Published: 16 March 2025 [Full Text]
LTBP2 variants in childhood glaucoma: Phenotypic expansion and clinical experience
Anshuman Verma, Arif O. Khan, Venkatesh Pochaboina, Sirisha Senthil
Published: 23 March 2025 [Full Text]
Syndromic forms of inherited retinal dystrophies: a comprehensive molecular diagnosis of consanguineous Pakistani families using capture panel sequencing
Aleesha Asghar, Sumbal Wazir, Shehzeen Fatima, Hussan Bilal, Muhammad Shoaib, Saqib Ur Rehman, Sumaira Altaf, Yumei Li, Kiran Afshan, Rui Chen, Sabika Firasat
Published: 26 March 2025 [Full Text]
DNA methyltransferase 1 regulates epithelial cell functions in corneal and eyelid development
Antonius Christianto, Maureen Mongan, Bo Xiao, Qin Wang, Alvaro Puga, Michael L. Robinson, Ying Xia
Published: 28 March 2025 [Full Text]
Astragaloside IV improves the survival rates of retinal ganglion cells in traumatic optic neuropathy by regulating autophagy mediated by the AMPK-MTOR-ULK signaling pathway
Wu Sun, Guojun Chao, Qiong Wu, Yanting Xia, Mengqiu Shang, Qiping Wei, Jian Zhou, Liang Liao
Published: 28 March 2025 [Full Text]
Serum pro-brain natriuretic peptide correlates with optical coherence tomography indices in diabetic retinopathy
Shivani Chaturvedi, Sandeep Saxena, Apjit Kaur, Pramod Kumar, Shivani Pandey, Abbas Ali Mahdi, Levent Akduman
Published: 28 March 2025 [Full Text]
Subretinal delivery of AAV5-mediated human Pde6b gene ameliorates the disease phenotype in a rat model of retinitis pigmentosa
Hee Jong Kim, Ji Hoon Kwak, Jun Sub Choi, Jin Kim, Seo Yun Moon, Steven Hyun Seung Lee, Heuiran Lee, Keerang Park, Joo Yong Lee, So-Yoon Won
Published: 28 March 2025 [Full Text]
Multikinase inhibition-mediated proliferative vitreoretinopathy therapy by nanoparticles in rabbits
Elif Arslan, Faruk Ozturk, Burcu Uner, Serkan Tureli, Sevda Fatma Muftuoglu, Cetin Tas
Published: 29 March 2025 [Full Text]
Inhibitory effects of ursolic acid on oxygen-induced mouse retinal neovascularization via intravitreal injection
Lu Yang, Fen Yang, Weiliang Zhang, Yanhua Wang, Peng Chen, Shufang Du, Xiaoyan Liu, Yan Gao, Junhua Shi, Peng Wang, Rui Li, Qiang Su
Published: 10 April 2025 [Full Text]
Mutation of beta-tubulin 4B gene (TUBB4B) causes autosomal dominant retinitis pigmentosa with sensorineural hearing loss in a multigenerational family
Cheryl Y. Gregory-Evans, Aaron W. Joe, Kevin Gregory-Evans
Published: 16 May 2025 [Full Text]
Unravelling γD-crystallin aggregation pathway to understand cataract formation using fluorescence correlation spectroscopy
Mangesh Bawankar, Bhaswati Sengupta, Sujata Malik, Pratik Sen, Ashwani K. Thakur
Published: 16 May 2025 [Full Text]
Erratum: Ablation of C3 modulates macrophage reactivity in the outer retina during photo-oxidative damage
Haihan Jiao, Jan M. Provis, Riccardo Natoli, Matt Rutar
Published: 30 June 2025 [Full Text]
Mutations in retinal cyclic nucleotide-gated channels identified in familial cases of inherited retinal dystrophies from Pakistan
Zainab Akhtar, Kiran Afshan, Yumei Li, Sumaira Altaf, Aleesha Asghar, Ume Sughra, Wajid Ali Khan, Haiba Kaul, Rui Chen, Sabika Firasat
Published: 2 September 2025 [Full Text]
Phenotype-genotype correlation of patients with congenital cataracts and hair anomalies
Qiwei Wang, Xiaoshan Lin, Dongni Wang, Tingfeng Qin, Wan Chen, Jingjing Chen, Xulin Zhang, Yongbin Lin, Zhuoling Lin, Jing Li, Xiaoyan Li, J. Fielding Hejtmancik, Weirong Chen
Published: 8 September 2025 [Full Text]
Unravelling γD-crystallin aggregation pathway to understand cataract formation using fluorescence correlation spectroscopy
Mangesh Bawankar, Bhaswati Sengupta, Sujata Malik, Pratik Sen, Ashwani K. Thakur
Published: 8 September 2025 [Full Text]
Cysteinyl leukotriene receptor 1 regulates cellular glucose levels in human retinal cells
Andreas Koller, Susanne Maria Brunner, Julia Preishuber-Pflügl, Daniela Mayr, Christian Runge, Herbert Anton Reitsamer, Andrea Trost
Published: 14 September 2025 [Full Text]
Bietti crystalline corneoretinal dystrophy: Advances in understanding and gene therapeutic approaches
Guangrong Zhao, Dayou Ding
Published: 20 September 2025 [Full Text]
Analysis of cytogenetic germline changes in Polish patients with retinoblastoma
Dorota Wicher, Danuta Sielska-Rotblum, Urszula Zawadzka-Wiech, Monika Kowalczyk-Rusak, Olga Rutynowska-Pronicka, Agnieszka Gietka, Elwira Kulicka, Marlena Mlynek
Published: 24 September 2025 [Full Text]
Intraocular pressure distribution in old and young cynomolgus monkeys following general anesthesia and mydriasis
Jinan Zhan, Zhidong Li, Guitong Ye, Yuan Zhang, Kezhe Chen, Rui Xie, Wei Liu, Jian Wu, Yingting Zhu, Yehong Zhuo
Published: 28 September 2025 [Full Text]
The genotype-phenotype association of retinitis pigmentosa in a Chinese population: Analysis of three new cases and literature review
Jianing Liu, Mengmeng Han, Xiao Zhang, Miaomiao Li, Shiguo Liu, Nan Jiang
Published: 28 September 2025 [Full Text]
DNA amplification from osmicated, plastic-embedded eye tissues
Jessica K. Niggel, Gustavo D. Aguirre, Leonardo Murgiano
Published: 28 September 2025 [Full Text]
Genetic variants through exome sequencing in Spanish patients affected by primary congenital glaucoma and juvenile open-angle glaucoma
Javier Laguna, Sara Labay-Tejado, Míriam Potrony, Laura Pinyol, Cristina Vendrell, Aurora Sánchez, Celia Badenas, Valeria Opazo-Toro, Meritxell Jodar, Elena Milla
Published: 29 September 2025 [Full Text]
Molecular insights into foveal hypoplasia: development, genetics, mechanisms, and models
Kevin Gregory-Evans, Cheryl Y. Gregory-Evans
Published: 3 October 2025 [Full Text]
Poor glycemic control impairs recovery from central retinal vein occlusion
Konstantin Y. Gushansky, Petteri Karesvuo, Raimo Tuuminen
Published: 3 October 2025 [Full Text]
Nitazoxanide reduced inflammatory markers and mitochondrial changes in human retinal endothelial cells grown in high glucose
Youde Jiang, Neeraja Purandare, Li Liu, Mohamed Al-Shabrawey, Lawrence I. Grossman, Jena J. Steinle
Published: 3 October 2025 [Full Text]
Inhibition of sortilin reduces neuronal and vascular damage after ischemia/reperfusion through reduced inflammatory and autophagy actions in retinal Müller cells
Li Liu, Youde Jiang, Jena J. Steinle
Published: 3 October 2025 [Full Text]
Vitreous from patients with proliferative diabetic retinopathy induced changes in neutrophil activation markers
Fátima Sofía Magaña-Guerrero, Alan Chew Bonilla, Beatriz Buentello-Volante, Norma Angelica Magaña-Guerrero, Oscar Vivanco‒Rojas, Alfredo Domínguez-López, Antonio López-Bolaños, Federico Graue-Wiechers, Yonathan Garfias
Published: 3 October 2025 [Full Text]
Hyperosmolar stress induces monocyte chemoattractant protein 1 expression in retinal pigmented epithelial arising retinal pigmented epithelial 19 cells
Moncef Ould Hamou, Maureen Masset, Célia Weber, Lisa Scifo, Sarah Libert, Angélic Bryla, Françoise Gregoire, Valérie Delforge, Nargis Bolaky, Azine Datlibagi, Jean-Yves Springael, Jason Perret, François Willermain, Christine Delporte
Published: 5 October 2025 [Full Text]
Ginger extract and selenium supplementation: A promising approach to improve diabetic retinopathy
Xiaohan Huang, Jing Li, Shaohua Tang, Jing Xu, Jiong Liu
Published: 5 October 2025 [Full Text]
Prevention of diabetic retinopathy in a rat model by a functional food mix
Krishna Kalyan Kalahasti, Pandarinath Savitikadi, Ch Uday Kumar, Marka Nagaraju, S. Sreenivasa Reddy, G. Bhanuprakash Reddy
Published: 25 October 2025 [Full Text]
Cassia polysaccharides can regulate the effect of low PAX6 expression on the function of ARPE-19 cells through the Wnt/β-catenin pathway
Luo Jincheng, Li Doudou, Li Jialin, Sun Xuewei, Wang Xue, Li Jie, Qiu Hongbin
Published: 1 November 2025 [Full Text]
System biology analysis reveals that Grm6 is associated with glutamate accumulation–induced scotopic vision impairment in diabetic mice
Ying Lian, Yanpu Zhao, Xiaoyu Yang, Hongjie He, Zhanyi Yang, Huanhuan Zhang, Guigang Yan, Lu Lu, Jia Mi, Geng Tian, Yanping Zhu
Published: 10 November 2025 [Full Text]
Genetic phenotypic characteristics and inheritance patterns of patients with achromatopsia at a large academic institution and a review of the literature and gene therapies
Sanjana Molleti, Pedro F. Monsalve, Richard N. Sather III, Jade Y. Moon, Jacie Ihinger, Sandra R. Montezuma
Published: 12 November 2025 [Full Text]
Unfolded proteins and aggregates: The role of proteostasis in pseudoexfoliation pathology
Bushra Hayat, Debasmita Pankaj Alone
Published: 17 November 2025 [Full Text]
Targeted sequencing with single-molecule molecular inversion probes highlights a gap in understanding the cause of Fuchs endothelial corneal dystrophy
Bushra Alayed, Danah Albuainain, Salina Siddiqui, Weijia Li, Ummey Hany, Seema Anand, Chris F. Inglehearn, Christopher M. Watson, Manir Ali
Published: 1 December 2025 [Full Text]
Deciphering the genetic basis of inherited retinal dystrophies via whole-exome sequencing in a Turkish cohort
Zulal Keles, Ozlem Ural Fatihoglu, Ziya Ayhan, Ali O. Saatci, Ahmet O. Caglayan, Ayfer Ulgenalp
Published: 12 December 2025 [Full Text]
Ferroptosis related genes in retinopathy of prematurity: Screening for potential pharmacological targets
Qiujuan Liao, Suyu Liu, Liqing Wei, Yuli Cai, Ying Li
Published: 12 December 2025 [Full Text]
Genetic and clinical characterization of suspected retinitis pigmentosa in a cohort of Brazilian patients
Sarah Pereira de Freitas Cenachi, Maria Frasson, Anna Laura Marques Nascentes, Anna Luiza Braga Albuquerque, Rodrigo Rezende Arantes, Virgínia Mares, Luiz Armando Cunha De Marco, Márcio Bittar Nehemy
Published: 20 December 2025 [Full Text]
Pseudomyopia and cycloplegic changes in young cynomolgus macaques
Guitong Ye, Yuan Zhang, Kezhe Chen, Rui Xie, Wei Liu, Chiwai Wong, Jinan Zhan, Ruiyu Luo, Shaofen Huang, Xiaohua Zhuo, Jian Wu, Yunxia Leng, Yehong Zhuo, Min Fu, Yingting Zhu
Published: 25 December 2025 [Full Text]
Molecular epidemiology of ABCA4-related retinopathies in Pakistan: report of disease-causing variants in 10 families and review of the literature
Zainab Akhtar, Sumaira Altaf, Yumei Li, Asma Arshad, Sawaira Subhani, Nomana Malik, Meng Wang, Kiran Afshan, Amtul Aziz, Rui Chen, Sabika Firasat
Published: 28 December 2025 [Full Text]
SNTB1 gene polymorphisms and risk of high myopia: meta-analysis and single-center validation
Jie Peng, Yina Wang, Jiaqing Lu, Ying Wang, Yongning Dong, Jie Fang, Xu Chen
Published: 30 December 2025 [Full Text]
Reticular fiber distribution in sclera: Key to understanding pathologic myopia and posterior staphylomas
Hirohiko Kakizaki, Heebae Ahn, Muhammad Abumanhal, Derrick Lian, Kan Ishijima, Hidenori Mito, Naoyuki Morishige
Published: 31 December 2025 [Full Text]
Monocyte/macrophage-derived IL-15 activates STAT5 to trigger the EFNA1/NCOA2-positive feedback loop, facilitating retinal angiogenesis in high-glucose environments
Lixin Zhang, Yan Guo
Published: 31 December 2025 [Full Text]