Role of the XIST-miR-181a-COL4A1 axis in the development and progression of keratoconus
Rui Tian, Lufei Wang, He Zou, Meijiao Song, Lu Liu, Hui Zhang
Published: 1 February 2020 [Full Text]
Novel mutations in LTBP2 identified in familial cases of primary congenital glaucoma
Bushra Rauf, Bushra Irum, Shahid Y. Khan, Firoz Kabir, Muhammad Asif Naeem, Sheikh Riazuddin, Radha Ayyagari, S. Amer Riazuddin
Published: 24 February 2020 [Full Text]
Copy number variations and multiallelic variants in Korean patients with Leber congenital amaurosis
Dongheon Surl, Saeam Shin, Seung-Tae Lee, Jong Rak Choi, Junwon Lee, Suk Ho Byeon, Sueng-Han Han, Hyun Taek Lim, Jinu Han
Published: 24 February 2020 [Full Text]
Role of the PGE2 receptor in ischemia-reperfusion injury of the rat retina
Cong Deng, Shanshan Chen, Xiongfeng Li, Hongdou Luo, Qinglin Zhang, Piaopiao Hu, Feifei Wang, Chan Xiong, Tao Sun, Xu Zhang
Published: 24 February 2020 [Full Text]
A method for gene knockdown in the retina using a lipid-based carrier
Joshua A. Chu-Tan, Nilisha Fernando, Riemke Aggio-Bruce, Adrian V. Cioanca, Krisztina Valter, Nektaria Andronikou, Xavier deMollerat du Jeu, Matt Rutar, Jan Provis, Riccardo Natoli
Published: 24 February 2020 [Full Text]
MicroRNA-29b-3p inhibits cell proliferation and angiogenesis by targeting VEGFA and PDGFB in retinal microvascular endothelial cells
Wenyi Tang, Jingli Guo, Ruiping Gu, Boya Lei, Xinyi Ding, Jun Ma, Gezhi Xu
Published: 24 February 2020 [Full Text]
Cell senescence altered the miRNA expression profile in porcine angular aqueous plexus cells
Chen Tan, Yiyan Yang, Maomao Song, Zhiwei Cao, Xinghuai Sun, Yuan Lei, Junyi Chen
Published: 25 February 2020 [Full Text]
A negative correlation of axial length with aqueous humor concentration of cytokines in patients with congenital cataracts
Fan Zhang, Pingjun Chang, Yinying Zhao, Yune Zhao
Published: 03 March 2020 [Full Text]
A simple and efficient method for generating human retinal organoids
Florian Regent, Holly Y. Chen, Ryan A. Kelley, Zepeng Qu, Anand Swaroop, Tiansen Li
Published: 03 March 2020 [Full Text]
A standardized method to assess the endogenous activity and the light–response of the retinal clock in mammals
H. Calligaro, C. Kinane, M. Bennis, C. Coutanson, O. Dkhissi-Benyahya
Published: 04 March 2020 [Full Text]
RNA sequencing analysis of long non-coding RNA expression in ocular posterior poles of guinea pig myopia models
Chao Geng, Yahong Li, Fang Guo, Jindan Wang, Yiyun Yue, Kewen Zhou, Ruihua Wei, Yan Zhang
Published: 05 March 2020 [Full Text]
Endogenous Wnt/β-catenin signaling in Müller cells protects retinal ganglion cells from excitotoxic damage
Fabian Boesl, Konstantin Drexler, Birgit Müller, Roswitha Seitz, Gregor R. Weber, Siegfried G. Priglinger, Rudolf Fuchshofer, Ernst R. Tamm, Andreas Ohlmann
Published: 05 March 2020 [Full Text]
The expression of cytokines in aqueous humor of high myopic patients with cataracts
Jing Shang Zhang, Jin Da Wang, Gu Yu Zhu, Jing Li, Ying Xiong, Mayinuer Yusufu, Hai Long He, Xiu Li Sun, Tian Ju, Yong Tao, Shou Zhi He, Xiu Hua Wan
Published: 05 March 2020 [Full Text]
A two-step method for identifying photopigment opsin and rhodopsin gene sequences underlying human color vision phenotypes
Shari R. Atilano, M. Cristina Kenney, Adriana D. Briscoe, Kimberly A. Jameson
Published: 05 March 2020 [Full Text]
Using BXD mouse strains in vision research: A systems genetics approach
Eldon E. Geisert, Robert W. Williams
Published: 06 March 2020 [Full Text]
Osmotic and hypoxic induction of osteopontin in retinal pigment epithelial cells: Involvement of purinergic receptor signaling
Margrit Hollborn, Ricarda Brück, Heidrun Kuhrt, Peter Wiedemann, Andreas Bringmann
Published: 08 March 2020 [Full Text]
p62/Sequestosome 1 levels increase and phosphorylation is altered in Cx50D47A lenses, but deletion of p62/sequestosome 1 does not improve transparency
Oscar Jara, Hubert Mysliwiec, Peter J. Minogue, Viviana M. Berthoud, Eric C. Beyer
Published: 18 March 2020 [Full Text]
Exome sequencing identifies PEX6 mutations in three cases diagnosed with Retinitis Pigmentosa and hearing impairment
Gema García-García, Iker Sanchez-Navarro, Elena Aller, Teresa Jaijo, Carla Fuster-Garcia, Ana Rodríguez-Munoz, Elena Vallejo, Juan José Tellería, Selma Vázquez, Sergi Beltrán, Sophia Derdak, Olga Zurita, Cristina Villaverde-Montero, Almudena Avila-Fernández, Marta Corton, Fiona Blanco-Kelly, Hakon Hakonarson, José M. Millán, Carmen Ayuso
Published: 18 March 2020 [Full Text]
Mutation spectrum of PAX6 and clinical findings in 95 Chinese patients with aniridia
Bing You, Xiaohui Zhang, Ke Xu, Yue Xie, Hanwen Ye, Yang Li
Published: 26 March 2020 [Full Text]
Glial cells of the human fovea
Kimberley Delaunay, Lilly Khamsy, Laura Kowalczuk, Emmanuelle Gelize, Alexandre Moulin, Michaël Nicolas, Leonidas Zografos, Patricia Lassiaz, Francine Behar-Cohen
Published: 01 April 2020 [Full Text]
The association between intravitreal ranibizumab therapy and serum cytokine concentrations in patients with diabetic macular edema
Sivashanth Gnanasekaran, Esther Bandala-Sanchez, Maria Kolic, Leonid Churilov, Sophie L. Rogers, Annie K. McAuley, Sukhpal S. Sandhu, Salmaan Qureshi, Lyndell L. Lim, Sanjeewa S. Wickremasinghe
Published: 01 April 2020 [Full Text]
Long-term evaluation of retinal morphology and function in a mouse model of oxygen-induced retinopathy
Olachi J. Mezu-Ndubuisi, Erica L. Macke, Raja Kalavacherla, Amy Amanda Nwaba, Andrew Suscha, Ismail S. Zaitoun, Akihiro Ikeda, Nader Sheibani
Published: 01 April 2020 [Full Text]
Proinflammatory cytokines trigger biochemical and neurochemical changes in mouse retinal explants exposed to hyperglycemic conditions
Gaganashree Shivashankar, Julie C. Lim, Monica L. Acosta
Published: 11 April 2020 [Full Text]
Clinical findings and RS1 genotype in 90 Chinese families with X-linked retinoschisis
Chunjie Chen, Yue Xie, Tengyang Sun, Lu Tian, Ke Xu, Xiaohui Zhang, Yang Li
Published: 11 April 2020 [Full Text]
A unique PRDM13-associated variant in a Georgian Jewish family with probable North Carolina macular dystrophy and the possible contribution of a unique CFH variant
Prasanthi Namburi, Samer Khateb, Segev Meyer, Tom Bentovim, Rinki Ratnapriya, Alisa Khramushin, Anand Swaroop, Ora Schueler-Furman, Eyal Banin, Dror Sharon
Published: 16 April 2020 [Full Text]
Effect of vitamin B12 supplementation on retinal lesions in diabetic rats
S. Sreenivasa Reddy, Y. K. Prabhakar, Ch. Uday Kumar, P. Yadagiri Reddy, G. Bhanuprakash Reddy
Published: 24 April 2020 [Full Text]
A pilot study to assess the effect of a three-month vitamin supplementation containing L-methylfolate on systemic homocysteine plasma concentrations and retinal blood flow in patients with diabetes
Doreen Schmidl, Kinga Howorka, Stephan Szegedi, Kristina Stjepanek, Stefan Puchner, Ahmed Bata, Ulrike Scheschy, Gerold Aschinger, René M. Werkmeister, Leopold Schmetterer, Gerhard Garhofer
Published: 24 April 2020 [Full Text]
Mutations in FYCO1 identified in families with congenital cataracts
Hira Iqbal, Shahid Y. Khan, Lin Zhou, Bushra Irum, Muhammad Ali, Mariya Ahmed, Mohsin Shahzad, Muhammad Hassaan Ali, Muhammad Asif Naeem, Sheikh Riazuddin, J. Fielding Hejtmancik, S. Amer Riazuddin
Published: 28 April 2020 [Full Text]
Clinical, histopathological, and in silico pathogenicity analyses in a pedigree with familial amyloidosis of the Finnish type (Meretoja syndrome) caused by a novel gelsolin mutation
Jesus Cabral-Macias, Leopoldo A. Garcia-Montaño, Mario Pérezpeña-Díazconti, Marisa-Cruz Aguilar, Guillermo Garcia, Carlos I. Vencedor-Meraz, Enrique O. Graue-Hernandez, Oscar F. Chacón-Camacho, Juan C. Zenteno
Published: 02 May 2020 [Full Text]
Review: Role of cAMP signaling in diabetic retinopathy
Jena J. Steinle
Published: 09 May 2020 [Full Text]
The correlation of cytokines and sensory hypersensitivity in mild dry eye patients characterized by symptoms outweighing signs
Bei Li, Ying Tian, Shuangyong Wang
Published: 09 May 2020 [Full Text]
The use of Matrigel combined with encapsulated cell technology to deliver a complement inhibitor in a mouse model of choroidal neovascularization
Balasubramaniam Annamalai, Nathaniel Parsons, Carlene Brandon, Bärbel Rohrer
Published: 15 May 2020 [Full Text]
Analysis of variants in Chinese individuals with primary open-angle glaucoma using molecular inversion probe (MIP)-based panel sequencing
Ting Liu, Chao Tang, Xiaolong Shi
Published: 21 May 2020 [Full Text]
Tyrosine triple mutated AAV2-BDNF gene therapy in an inner retinal injury model induced by intravitreal injection of N–methyl-D-aspartate (NMDA)
Asaka Lee Shiozawa, Tsutomu Igarashi, Maika Kobayashi, Kenji Nakamoto, Shuhei Kameya, Shigeto Fujishita, Hiroshi Takahashi, Takashi Okada
Published: 13 August 2020 [Full Text]
Biallelic RP1-associated retinal dystrophies: Expanding the mutational and clinical spectrum
Rachel M. Huckfeldt, Florin Grigorian, Emily Place, Jason I. Comander, Demetrios Vavvas, Lucy H. Young, Paul Yang, Maria Shurygina, Eric A. Pierce, Mark E. Pennesi
Published: 03 June 2020 [Full Text]
Technical brief: Direct, real-time electrochemical measurement of nitric oxide in ex vivo cultured human corneoscleral segments
Pinkal D. Patel, Ramesh B. Kasetti, Swapnil K. Sonkusare, Gulab S. Zode
Published: 05 June 2020 [Full Text]
Clinical heterogeneity in retinitis pigmentosa caused by variants in RP1 and RLBP1 in five extended consanguineous pedigrees
Muawyah Al-Bdour, Svenja Pauleck, Zain Dardas, Raghda Barham, Dema Ali, Sami Amr, Lina Mustafa, Mohammed Abu-Ameerh, Ranad Maswadi, Belal Azab, Abdalla Awidi
Published: 19 June 2020 [Full Text]
A systems genetics approach to revealing the Pdgfb molecular network of the retina
Shasha Li, Fuyi Xu, Lin Liu, Rong Ju, Jonas Bergquist, Qing Yin Zheng, Jia Mi, Lu Lu, Xuri Li, Geng Tian
Published: 19 June 2020 [Full Text]
Correlations between vitreous cytokine levels and inflammatory cells in fibrovascular membranes of patients with proliferative diabetic retinopathy
Mojca Urbančič, Daniel Petrovič, Aleksandra Milutinović Živin, Peter Korošec, Matjaž Fležar, Mojca Globočnik Petrovič
Published: 26 June 2020 [Full Text]
Differential DNA methylation patterns in human Schlemm’s canal endothelial cells with glaucoma
Jingwen Cai, Michelle D. Drewry, Kristin Perkumas, W. Michael Dismuke, Michael A. Hauser, W. Daniel Stamer, Yutao Liu
Published: 26 June 2020 [Full Text]
Tetramethylpyrazine protects mice retinas against sodium iodate–induced oxidative injury
Jie Huang, Yan Liu, Ke Mao, Qing Gu, Xingwei Wu
Published: 27 June 2020 [Full Text]
Genetic factors associated with treatment response to reduced-fluence photodynamic therapy for chronic central serous chorioretinopathy
Mayuka Hayashida, Akiko Miki, Shunichiro Nakai, Wataru Matsumiya, Hisanori Imai, Sentaro Kusuhara, Shigeru Honda, Makoto Nakamura
Published: 04 July 2020 [Full Text]
Immunohistochemical study of STAT3, HIF-1α and VEGF in pterygium and normal conjunctiva: Experimental research and literature review
Shiqi Dong, Xiying Wu, Yuting Xu, Guohua Yang, Ming Yan
Published: 26 July 2020 [Full Text]
Interleukin-6 promotes proliferative vitreoretinopathy by inducing epithelial-mesenchymal transition via the JAK1/STAT3 signaling pathway
Xiaoyun Chen, Weimin Yang, Xiaoqian Deng, Shaobi Ye, Wei Xiao
Published: 29 July 2020 [Full Text]
Changes in melatonin receptor expression in a murine model of glaucoma
Alejandro Martínez-Águila, Begoña Fonseca, María J. Pérez de Lara, M. Teresa Miras-Portugal, Rosa Gómez-Villafuertes, Gonzalo Carracedo, Jesús Pintor
Published: 29 July 2020 [Full Text]
Thrombin alters the synthesis and processing of CYR61/CCN1 in human corneal stromal fibroblasts and myofibroblasts through multiple distinct mechanisms
Emily A. Andreae, Debra J. Warejcka, Sally S. Twining
Published: 29 July 2020 [Full Text]
Accumulation of Asn450Tyr mutant myocilin in ER promotes apoptosis of human trabecular meshwork cells
Xuejing Yan, Shen Wu, Qian Liu, Yang Li, Wei Zhu, Jingxue Zhang
Published: 29 July 2020 [Full Text]
Erratum: Inhibitory effects of S100A4 gene silencing on alkali burn-induced corneal neovascularization: an in vivo study
Published: 09 August 2020 [Full Text]
Full retraction: Sasirekha Krishnan, Shruthi Lakshmanan, Geetha Krishnan Iyer, Krishnan UmaMaheswari, Subramanian Krishnakumar. The role of signaling pathways in the expansion of corneal epithelial cells in serum-free B27 supplemented medium. Mol Vis. 2010; 16:1169-1177
Published: 19 August 2020 [Full Text]
TRPV1, TRPA1, and TRPM8 are expressed in axon terminals in the cornea: TRPV1 axons contain CGRP and secretogranin II; TRPA1 axons contain secretogranin 3
Leslayann C. Schecterson, Alexander A. Pazevic, Ruian Yang, Kimberly Matulef, Sharona E. Gordon
Published: 22 August 2020 [Full Text]
Genotypes and phenotypes of genes associated with achromatopsia: A reference for clinical genetic testing
Wenmin Sun, Shiqiang Li, Xueshan Xiao, Panfeng Wang, Qingjiong Zhang
Published: 22 August 2020 [Full Text]
CP49 and filensin intermediate filaments are essential for formation of cold cataract
Yuxing Li, Xi Liu, Chun-hong Xia, Paul G. FitzGerald, Rachel Li, Jessica Wang, Xiaohua Gong
Published: 23 August 2020 [Full Text]
The impact of the c.5603A>T hypomorphic variant on founder mutation screening of ABCA4 for Stargardt disease in South Africa
Nicole Midgley, Lisa Roberts, George Rebello, Raj Ramesar
Published: 23 August 2020 [Full Text]
Alterations in proteome of human sclera associated with primary open-angle glaucoma involve proteins participating in regulation of the extracellular matrix
Elena N. Iomdina, Natalya K. Tikhomirova, Alexander M. Bessmertny, Marina V. Serebryakova, Viktoriia E. Baksheeva, Arthur O. Zalevsky, Vladislav I. Kotelin, Olga A. Kiseleva, Sbrui M. Kosakyan, Andrey A. Zamyatnin, Pavel P. Philippov, Evgeni Yu. Zernii
Published: 02 September 2020 [Full Text]
Tofacitinib inhibits the development of experimental autoimmune uveitis and reduces the proportions of Th1 but not of Th17 cells
So Jin Bing, Cancan Lyu, Biying Xu, Wambui S. Wandu, Samuel J. Hinshaw, Yasuko Furumoto, Rachel R. Caspi, Massimo Gadina, Igal Gery
Published: 26 September 2020 [Full Text]
Review: Intraflagellar transport proteins in the retina
Chitra Kannabiran
Published: 04 October 2020 [Full Text]
Genetic and environmental risk factors for extramacular drusen
Lebriz Altay, Xavier Subiras, Laura Lorés de Motta, Tina Schick, Aileen Berghold, Carel B. Hoyng, Anneke I. den Hollander, Sascha Fauser, Srinivas R. Sadda, Sandra Liakopoulos
Published: 04 October 2020 [Full Text]
A large deletion spanning PITX2 and PANCR in a Chinese family with Axenfeld-Rieger syndrome
Yayun Qin, Pang Gao, Shanshan Yu, Jingzhen Li, Yuwen Huang, Danna Jia, Zhaohui Tang, Pengcheng Li, Fei Liu, Mugen Liu
Published: 04 October 2020 [Full Text]
Ablation of C3 modulates macrophage reactivity in the outer retina during photo-oxidative damage
Haihan Jiao, Jan M. Provis, Riccardo Natoli, Matt Rutar
Published: 10 October 2020 [Full Text]
Neuroprotective effects of Acer palmatum thumb. leaf extract (KIOM-2015E) against ischemia/reperfusion-induced injury in the rat retina
Yeoun-Hee Kim, Tae Woo Oh, Eunhee Park, Nam-Hui Yim, Won-Kyung Cho, Jin-Yeul Ma
Published: 10 October 2020 [Full Text]
An optimized protocol for retina single-cell RNA sequencing
Benjamin R. Fadl, Seth A. Brodie, Michael Malasky, Joseph F. Boland, Michael C. Kelly, Matthew W. Kelley, Erich Boger, Robert Fariss, Anand Swaroop, Laura Campello
Published: 10 October 2020 [Full Text]
Inflammation and diabetic retinopathy
Nil Irem Ucgun, Cenk Zeki-Fikret, Zuhal Yildirim
Published: 15 October 2020 [Full Text]
Levels of the oxidative stress biomarker malondialdehyde in tears of patients with central serous chorioretinopathy relate to disease activity
Alejandra Daruich, Jean-Jacques Sauvain, Alexandre Matet, Simone Eperon, Claude Schweizer, Aurélie Berthet, Brigitta Danuser, Francine Behar-Cohen
Published: 15 October 2020 [Full Text]
Arteriovenous crossing in retinal vessels of mice, rats, and pigs
Gottfried Martin, Kira L. Wefelmeyer, Felicitas Bucher, Günther Schlunck, Hansjürgen T. Agostini
Published: 15 October 2020 [Full Text]
Role of inhibitor of differentiation 3 gene in cellular differentiation of human corneal stromal fibroblasts
Suneel Gupta, Lynn M. Martin, Nishant R. Sinha, Kaitlin E. Smith, Prashant R. Sinha, Emilee M. Dailey, Nathan P. Hesemann, Rajiv R. Mohan
Published: 25 November 2020 [Full Text]
A mutation in DOP1B identified as a probable cause for autosomal recessive Peters anomaly in a consanguineous family
Ensieh Darbari, Davood Zare-Abdollahi, Afagh Alavi, Mozhgan Rezaei Kanavi, Sepehr Feizi, Seyed Bagher Hosseini, Alireza Baradaran-Rafii, Hamid Ahmadieh, Shohreh Issazadeh-Navikas, Elahe Elahi
Published: 25 November 2020 [Full Text]
Single-cell transcriptomic profiling provides insights into retinal endothelial barrier properties
Mark I. Watson, Peter Barabas, Mary McGahon, Megan McMahon, Marc A. Fuchs, Tim M. Curtis, David A. Simpson
Published: 27 November 2020 [Full Text]
The regulatory role of vasoactive intestinal peptide in lacrimal gland ductal fluid secretion: A new piece of the puzzle in tear production
Orsolya Berczeli, Dóra Szarka, Gréta Elekes, Eszter Vizvári, László Szalay, János Almássy, László Tálosi, Chuanqing Ding, Edit Tóth-Molnár
Published: 06 December 2020 [Full Text]
A hospital-based five-year prospective study on the prevalence of Leber’s hereditary optic neuropathy with genetic confirmation
Poigaialwar Gowri, Shanmugam Mahesh Kumar, Ayyasamy Vanniarajan, Devarajan Bharanidharan, Periasamy Sundaresan
Published: 28 December 2020 [Full Text]
Osmotic regulation of aquaporin-8 expression in retinal pigment epithelial cells in vitro: Dependence on KATP channel activation
Benjamin Schnabel, Heidrun Kuhrt, Peter Wiedemann, Andreas Bringmann, Margrit Hollborn
Published: 30 December 2020 [Full Text]
In vitro generation of primary cultures of human hyalocytes
Raffaele Nuzzi, Loredana Bergandi, Lorenzo Coda Zabetta, Laura D’Errico, Francesco Riscaldino, Silvia Menegon, Francesca Silvagno
Published: 30 December 2020 [Full Text]