Association of ABCA1 (rs2472493) and GAS7 (rs9913911) gene variants with primary open-angle glaucoma in a Brazilian population
Manoel Vinicius Rocha Araki, Yuri Carvalho Oiamore Silva, Thiago Adalton Rosa Rodrigues, Flavia Fialho Bajano, Bruno Batista de Souza, Fernando Ferreira Costa, Vital Paulino Costa, Mônica Barbosa de Melo, José Paulo Cabral de Vasconcellos
Published: 22 February 2022 [Full Text]
GPX1 knockout, not catalase knockout, causes accelerated abnormal optical aberrations and cataract in the aging lens
Kulandaiappan Varadaraj, Junyuan Gao, Richard T. Mathias, S. Sindhu Kumari
Published: 22 February 2022 [Full Text]
Relatively mild blue cone monochromacy phenotype caused by various haplotypes in the L- and M-cone opsin genes
Samer Khateb, Aya Shemesh, Ashly Offenheim, Ruth Sheffer, Tamar Ben-Yosef, Itay Chowers, Rina Leibu, Britta Baumann, Bernd Wissinger, Susanne Kohl, Eyal Banin, Dror Sharon
Published: 22 February 2022 [Full Text]
Ocular manifestations of Chinese patients with copy number variants in the NDP gene
Li Huang, Linyan Zhang, Xiaoyu Li, Jinglin Lu, Limei Sun, Limei Chen, Xiaoyan Ding, Zhan Li
Published: 25 March 2022 [Full Text]
Glial cell line-derived neurotrophic factor (GDNF) in patients with primary open-angle glaucoma and age-related cataract
Alexander A. Shpak, Alla B. Guekht, Tatiana A. Druzhkova, Anna A. Troshina, Natalia V. Gulyaeva
Published: 15 May 2022 [Full Text]
Novel homozygous mutations in the transcription factor NRL cause non-syndromic retinitis pigmentosa
Mohammed E. El-Asrag, Marta Corton, Martin McKibbin, Almudena Avila-Fernandez, Moin D. Mohamed, Fiona Blanco-Kelly, Carmel Toomes, Chris F. Inglehearn, Carmen Ayuso, Manir Ali
Published: 17 May 2022 [Full Text]
Novel SIX6 mutations cause recessively inherited congenital cataract, microcornea, and corneal opacification with or without coloboma and microphthalmia
Evangelia S. Panagiotou, Narcis Fernandez-Fuentes, Layal Abi Farraj, Martin McKibbin, Nursel H. Elçioglu, Hussain Jafri, Eren Cerman, David A. Parry, Clare V. Logan, Colin A. Johnson, Chris F. Inglehearn, Carmel Toomes, Manir Ali
Published: 17 May 2022 [Full Text]
Protective effect of Glutaredoxin 1 against oxidative stress in lens epithelial cells of age-related nuclear cataracts
Qi Fan, Dan Li, Zhennan Zhao, Yongxiang Jiang, Yi Lu
Published: 19 May 2022 [Full Text]
Comprehensive circular RNA expression profiling with associated ceRNA network in orbital venous malformation
Jie Yu, Peiwei Chai, Yixiong Zhou, Renbing Jia, Yefei Wang
Published: 20 May 2022 [Full Text]
Whole-exome sequencing identified genes known to be responsible for retinitis pigmentosa in 28 Chinese families
Chang Shen, Bing You, Yu-Ning Chen, Yang Li, Wei Li, Wen-Bin Wei
Published: 06 June 2022 [Full Text]
Diquafosol ophthalmic solution enhances mucin expression via ERK activation in human conjunctival epithelial cells with hyperosmotic stress
Hyun Jung Lee, Soonwon Yang, Eun Jeong Cheon, Soojung Shin, Yong-Soo Byun, Hyun Seung Kim, So-Hyang Chung
Published: 30 June 2022 [Full Text]
TNFAIP3 is anti-inflammatory in the retinal vasculature
Li Liu, Youde Jiang, Jena J. Steinle
Published: 30 June 2022 [Full Text]
Review: New horizons in retinoblastoma treatment: an updated review article
Fatemeh Azimi, Reza Mirshahi, Masood Naseripour
Published: 11 July 2022 [Full Text]
αA and αB peptides from human cataractous lenses show antichaperone activity and enhance aggregation of lens proteins
Om Srivastava, Landon Wilson, Stephen Barnes, Kiran Srivastava, Roy Joseph
Published: 06 August 2022 [Full Text]
Oral administration of a dual ETA/ETB receptor antagonist promotes neuroprotection in a rodent model of glaucoma
Bindu Kodati, Nolan R. McGrady, Hayden B. Jefferies, Dorota L. Stankowska, Raghu R. Krishnamoorthy
Published: 07 August 2022 [Full Text]
Hsa-miR-150-5p inhibits Wnt-β-catenin signaling in human corneal epithelial stem cells
Lavanya Kalaimani, Bharanidharan Devarajan, Venkatesh Prajna Namperumalsamy, Muthukkaruppan Veerappan, Julie T. Daniels, Gowri Priya Chidambaranathan
Published: 07 August 2022 [Full Text]
Dopachrome tautomerase is a retinoblastoma-specific gene, and its proximal promoter is preferentially active in human retinoblastoma cells
Kanya Moolsuwan, Tiravut Permpoon, Chanachai Sae-Lee, Mongkol Uiprasertkul, Viroj Boonyaratanakornkit, Pa-thai Yenchitsomanus, Naravat Poungvarin, La-ongsri Atchaneeyasakul
Published: 07 August 2022 [Full Text]
Identification of numerous novel disease-causing variants in patients with inherited retinal diseases, combining careful clinical-functional phenotyping with systematic, broad NGS panel-based genotyping
Priya R. Gupta, Wajiha Kheir, Bo Peng, Jie Duan, John P-W. Chiang, Alessandro Iannaccone
Published: 16 August 2022 [Full Text]
Using optical coherence tomography angiography as a biomarker of retinopathy severity and treatment for diabetic retinopathy
Melanie Scheive, Kathryn L. Reinhart, Amir R. Hajrasouliha
Published: 19 August 2022 [Full Text]
Untargeted metabolomic analysis of aqueous humor in diabetic macular edema
Kai On Chu, Tina InLam Chan, Kwok Ping Chan, Yolanda WongYing Yip, Malini Bakthavatsalam, Chi Chiu Wang, Chi Pui Pang, Marten E. Brelen
Published: 19 August 2022 [Full Text]
Hyposmotic stress causes ATP release in a discrete zone within the outer cortex of rat lens
Haruna Suzuki-Kerr, Kerry L. Walker, Min-Hi Han, Julie C. Lim, Paul J. Donaldson
Published: 04 September 2022 [Full Text]
The phenotypic spectrum of ADAMTSL4-associated ectopia lentis: Additional cases, complications, and review of literature
Lachlan S.W. Knight, Sean Mullany, Deepa A. Taranath, Jonathan B. Ruddle, Christopher P. Barnett, Suzanne C.E.H. Sallevelt, Ella C. Berry, Henry N. Marshall, Georgina L. Hollitt, Emmanuelle Souzeau, Jamie E. Craig, Owen M. Siggs
Published: 04 September 2022 [Full Text]
The long noncoding RNA MALAT1/microRNA-598-3p axis regulates the proliferation and apoptosis of retinoblastoma cells through the PI3K/AKT pathway
Xiaoli Lin, Xionggao Huang, Ling Wang, Weixian Liu
Published: 04 September 2022 [Full Text]
Nestin contributes to laser choroidal and retinal neovascularization
Sofiane Miloudi, Maud Valensi, Mohamed El Sanharawi, Marc M. Abitbol, Francine Behar-Cohen, Claudine Versaux-Botteri
Published: 04 September 2022 [Full Text]
A five-year follow-up of ABCA4 carriers showing deterioration of retinal function and increased structural changes
Ulrika Kjellström, Sten Andréasson
Published: 01 October 2022 [Full Text]
Structural and functional analysis of SNP rs76740365 G>A in exon-3 of the alpha A-crystallin gene in lens epithelial cells
Zhennan Zhao, Yang Sun, Qi Fan, Yongxiang Jiang, Yi Lu
Published: 01 October 2022 [Full Text]
Isolation efficiency of collagenase and EDTA for the culture of corneal endothelial cells
Kim Santerre, Stéphanie Proulx
Published: 02 October 2022 [Full Text]
Oxidative stress alters transcript localization of disease-associated genes in the retinal pigment epithelium
Tadeusz J. Kaczynski, Elizabeth D. Au, Michael H. Farkas
Published: 02 October 2022 [Full Text]
Clinical and genetic studies of 17 Han Chinese pedigrees and 31 sporadic patients with blepharophimosis-ptosis-epicanthus inversus syndrome
Yuan Wang, Qian Wu, Wenhong Cao, Lijuan Huang, Wen Liu, Cheng Li, Ningdong Li
Published: 06 October 2022 [Full Text]
Autosomal dominant retinitis pigmentosa with incomplete penetrance due to an intronic mutation of the PRPF31 gene
Tahleel Ali-Nasser, Shiri Zayit-Soudry, Eyal Banin, Dror Sharon, Tamar Ben-Yosef
Published: 06 October 2022 [Full Text]
Association of IGF1 polymorphisms with exotropia in a Pakistani cohort
Zainab Zehra, Netasha Khan, Minhal Nadeem, Sorath Noorani Siddiqui, Christopher S. von Bartheld, Maleeha Azam, Raheel Qamar
Published: 06 October 2022 [Full Text]
Sulforaphane recovers cone function in an Nrf2-dependent manner in middle-aged mice undergoing RPE oxidative stress
Xiaoping Qi, Dorothy A. Walton, Kendra S. Plafker, Michael E. Boulton, Scott M. Plafker
Published: 16 October 2022 [Full Text]
Morphological, biochemical, and transcriptomic characterization of iPSC-derived human RPE cells from normal and Smith-Lemli-Opitz syndrome patients
Michael H. Farkas, Lara A. Skelton, Sriganesh Ramachandra-Rao, Elizabeth Au, Steven J. Fliesler
Published: 12 November 2022 [Full Text]
Neural differentiation of human retinal pigment epithelial cells on alginate/gelatin substrate
Hoda Shamsnajafabadi, Zahra-soheila Soheili, Shahram Samiee, Hamid Ahmadieh, Ehsan Ranaei Pirmardan, Massoud Haghighi
Published: 12 December 2022 [Full Text]
In vitro induction and intraocular application in oxygen-induced retinopathy of adipose-derived mesenchymal stem cells
Lvlv Zhou, Haifeng Zhang, Sarina Wu, Yuhong He, Kai Guo
Published: 21 December 2022 [Full Text]
Lipoxin A4 alleviates inflammation in Aspergillus fumigatus–stimulated human corneal epithelial cells by Nrf2/HO-1 signaling pathway
Xudong Peng, Xiaojia Zhu, Junjie Luan, Jing Lin, Yingxue Zhang, Qian Wang, Guiqiu Zhao
Published: 21 December 2022 [Full Text]
Psychological stress induces moderate pathology in the ganglion cell layer in mice
Dandan Zhang, Nannan Sun, Congcong Guo, Jun Hui Lee, Jiamin Zhang, Zhenni Zhao, Xiaowei Yu, Ying Han, Jian Ge, Zhigang Fan
Published: 21 December 2022 [Full Text]
Safety evaluation and pharmacodynamics of minocycline hydrochloride eye drops
Xiaoli Li, Wenhua Zhang, Zhiqiang Ye, Shuaili Pei, Dongliang Zheng, Lin Zhu
Published: 21 December 2022 [Full Text]
Whole exome sequencing revealed novel pathogenic variants in Vietnamese patients with FEVR
Duong Thu Trang, Nguyen Minh Phu, Do Manh Hung, Vu Phuong Nhung, Nguyen Ngan Ha, Ma Thi Huyen Thuong, Tran Thi Bich Ngoc, Nguyen Xuan Hiep, Nguyen Dang Ton, Nong Van Hai, Nguyen Hai Ha
Published: 21 December 2022 [Full Text]
Novel segmentation algorithm for high-throughput analysis of spectral domain-optical coherence tomography imaging of teleost retinas
Kent R. Barter, Hélène Paradis, Robert L. Gendron, Josué A. Lily Vidal, Oscar Meruvia-Pastor
Published: 31 December 2022 [Full Text]
Epac1 and PKA agonists inhibit ROS to reduce NLRP3 inflammasome proteins in retinal endothelial cells
Li Liu, Youde Jiang, Jena J. Steinle
Published: 31 December 2022 [Full Text]
PET imaging of retinal inflammation in mice exposed to blue light using [18F]-DPA-714
Yuan Chen, Yixiang Zhou, Xue Zhu, Ge Yan, Donghui Pan, Lizhen Wang, Min Yang, Ke Wang
Published: 31 December 2022 [Full Text]
Efficacy of sodium polyanethol sulfonate on herpes simplex virus-1 infection in vitro
Jingwei Li, Chao Cheng, Tianlan Lin, Ran Xue, Xiuping Liu, Kaili Wu
Published: 31 December 2022 [Full Text]
Chronic ocular sequelae in Stevens–Johnson syndrome: a genetic association study
Sushil K. Sangwan, Namrata Sharma, Tushar Agarwal, Neena Khanna, Ravindra M. Pandey, Arundhati Sharma, Rasik B. Vajpayee
Published: 31 December 2022 [Full Text]
Analysis of hemopexin plasma levels in patients with age-related macular degeneration
Susette Lauwen, Bjorn Bakker, Eiko K. de Jong, Sascha Fauser, Carel B. Hoyng, Dirk J. Lefeber, Anneke I. den Hollander
Published: 31 December 2022 [Full Text]
Full retractions: 1. Pei-Liang Chen, Ya-Wen Cheng, Chun-Chi Chiang, Sung Huei Tseng, Pak Sam Chau, Yi-Yu Tsai. Hypermethylation of the p16 gene promoter in pterygia and its association with the expression of DNA methyltransferase 3b. Molecular Vision 2006; 12:1411-1416
2. Te-Jen Lai, Yi-Yu Tsai, Ya-Wen Cheng, Chun-Chi Chiang, Huei Lee, Ming-Chih Chou, Julia Hueimei Chang. An association between BPDE-like DNA adduct levels and P53 gene mutation in pterygium. Mol Vis. 2006; 12:1687-91.
3. Chun-Chi Chiang, Ya-Wen Cheng, Chien-Lin Lin, Huei Lee, Fuu-Jen Tsai, Sung-Huei Tseng, Yi-Yu Tsai. Cyclooxygenase 2 expression in pterygium. Molecular Vision 2007; 13:635-638.
4. Yi-Yu Tsai, Chi-Chung Chang, Chun-Chi Chiang, Kun-Tu Yeh, Pei-Liang Chen, Chi-Huang Chang, Ming-Chih Chou, Huei Lee, Ya-Wen Cheng. HPV infection and p53 inactivation in pterygium. Molecular Vision 2009; 15:1092-1097.
5. Jai-Nien Tung, Heng-Hsiung Wu, Chun-Chi Chiang, Yi-Yu Tsai, Ming-Chih Chou, Huei Lee, Ya-Wen Cheng. An association between BPDE-like DNA adduct levels and CYP1A1 and GSTM1 polymorphisma in pterygium. Molecular Vision 2010; 16:623-629
6. Pei-Liang Chen, Kun-Tu Yeh, Yi-Yu Tsai, Hank Koeh, Yu-Ling Liu, Huei Lee, Ya-Wen Cheng. XRCC1, but not APE1 and hOGG1 gene polymorphisms is a risk factor for pterygium. Molecular Vision 2010; 16:991-996.
7. Chi-Hsien Young, Yu-Te Chiu, Tung-Sheng Shih, Wan-Ru Lin, Chun-Chi Chiang, Ying-Erh Chou, Ya-Wen Cheng, Yi-Yu Tsai. E-cadherin promoter hypermethylation may contribute to protein inactivation in pterygia. Molecular Vision 2010; 16:1047-1053.
8. Chi-Hsien Young, Yu-Lun Lo, Yi-Yu Tsai, Tung-Sheng Shih, Huei Lee, Ya-Wen Cheng. CYP1A1 gene polymorphisms as a risk factor for pterygium. Molecular Vision 2010; 16:1054-1058
9. Jai-Nien Tung, Chun-Chi Chiang, Yi-Yu Tsai, Ying-Yi Chou, Kun-Tu Yeh, Huei Lee, Ya-Wen Cheng. CyclinD1 protein expressed in pterygia is associated with β-catenin protein localization. Molecular Vision 2010; 16:2733-2738.
Published: 31 December 2022 [Full Text]