Figure 6. Increased putative LESC marker expression in the diabetic limbus in organ culture upon c-met overexpression. c-Met gene transduction leads to elevated expression of K15, K17, and ΔNp63α in the limbus of organ-cultured diabetic corneas. The staining intensity and regularity appear more normal (compare with Figure 1 and Figure 2). Note that in organ cultures keratins (especially K17) can also be seen in suprabasal epithelial layers. e, epithelium, s, stroma. Bar=20 μm.