Table 4 of Wistow, Mol Vis 2002; 8:185-195.


Table 4. Transcripts for growth factors, cytokines and growth factor related genes in the iris libraries

Entries in black are from the un-normalized bx collection; those in red are from the normalized fg collection. Representative GenBank entries are shown, along with the appropriate Unigene, chromosomal location and the number of ESTs identified using GRIST.

Description                                      GenBank     UniGene   Chromosome      #
----------------------------------------------   ---------   -------   -------------   -
insulin-like growth factor binding protein 7     NM_001553   119206    4q12            7
  (IGFBP7)
insulin-like growth factor binding protein 6     BC003507    274313    12q13           4
  (IGFBP6)
insulin-like growth factor binding protein 4     M62403      1516      17q12-q21.1     3
  (IGFBP4)
pigment epithelium derived factor (PEDF)         BC000522    173594    17p13.1         2
similar to EGF-related protein SCUBE1 [Mus                   187285                    2
  musculus]
colony stimulating factor 1 (CSF-1)              M27087      173894    1p21-p13        1
fibroblast growth factor receptor 1              X66945      748       8p11.2-p11.1    1
fibroblast growth factor receptor 3 (FGFR3)      AF245114    1420      4p16.3          1
growth factor receptor-bound protein 2           XM_008198   296381    17q24-q25       1
insulin-like growth factor 2 receptor (IGF2R)    NM_000876   76473     6q26            1
insulin-like growth factor binding protein 5     AF055033    107169    2q33-q36        1
  (IGFBP5)
interleukin 13 receptor, α 1                     NM_001560   285115    X               1
interleukin 18 binding protein                   AF110799    279863    11q13           1
Iris-expressed growth factor IEGF/hSCDGF-B       AB033832    112885    11              1
lymphotoxin b receptor (TNFR superfamily,        AK027080    1116      12p13           1
  member 3)
macrophage migration inhibitory factor           BC000447    73798     22q11.23        1
pre-B-cell colony-enhancing factor               NM_005746   239138    7               1
stem cell growth factor; lymphocyte secreted     AF020044    105927    19q13.3         1
  C-type lectin
tumor necrosis factor receptor superfamily,      BC002794    279899    1p36.3-p36.2    1
  member 14
tumor necrosis factor receptor superfamily,      M63121      159       12p13.2         1
  member 1A
tumor necrosis factor receptor 1A                M33294      159       12p13.2         4
colony stimulating factor 1 (CSF-1)              M37435      173894    1p21-p13        2
insulin-like growth factor 2 (somatomedin A)     AK025719    251664    11p15.5         2
insulin-like growth factor binding protein 2     XM_002636   162       2q33-q34        2
  (36kD) (IGFBP2)
insulin-like growth factor binding protein 5     AF055033    107169    2q33-q36        2
  (IGFBP5)
insulin-like growth factor binding protein 6     M62402      274313    12q13           2
  (IGFBP6)
vascular endothelial growth factor B             U43368      78781     11q13           2
insulin-like growth factor binding protein 3     BC000013    77326     7p13-p12        1
  (IGFBP3)
insulin-like growth factor binding protein,      NM_004970   839       16              1
  acid labile subunit
interleukin 13 receptor, α2                      Y08768.1    25954     Xq13.1-q28      1
latent transforming growth factor-b binding      AF051344    85087     19q13.1-q13.2   1
  protein 4S
platelet-derived growth factor receptor, α       M21574      74615     4q11-q13        1
  polypeptide
platelet-derived growth factor receptor, β       J03278      76144     5q31-q32        1
  polypeptide
pleiotrophin (heparin binding growth factor 8)   M57399      44        7q33-q34        1
stromal cell-derived factor 1 (SDF1), mRNA       XM_005815   237356    10q11.1         1
transforming growth factor, β3                   J03241      2025      14q24           1
transforming growth factor, β receptor III       AJ251961    79059     1p33-p32        1
tumor necrosis factor receptor superfamily,      NM_001250   25648     20q12-q13.2     1
  member 5
tumor necrosis factor receptor superfamily,      AF104419    278556    20q13           1
  member 6b, decoy
vascular endothelial growth factor (VEGF)        AF024710    73793     6p12            1
88% protein similarity to: fibroblast growth                                           1
  factor receptor 4, isoform 2 precursor
93% protein similarity to: midkine (neurite                                            1
  growth-promoting factor 2)

Wistow, Mol Vis 2002; 8:185-195 <http://www.molvis.org/molvis/v8/a25/>
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