Figure 6 of Hamer, Mol Vis 2000; 6:265-286.

Figure 6. RecRK model does not account for Murnick & Lamb data with τR rate-limiting

With τR rate-limiting in the RecRK model, the reduction in model Testflash Tsat (blue curve) cannot exceed the magnitude of the delay between Pre- and Test flashes; i.e., the model results are always above the dashed blue line with slope -1. This contrasts with the Murnick & Lamb data (red curve versus red dashed line). This failure rules out a model structure in which R* lifetime is rate-limiting and in which early Ca++ feedback occurs solely at R* lifetime (via RecRK; [1]).

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Hamer, Mol Vis 2000; 6:265-286 <>
©2000 Molecular Vision <>
ISSN 1090-0535