Figure 1 of
Weiss, Mol Vis 4:27, 1998.
Figure 1. Comparison of partial fragments of GRK7 and GRK1 from ground squirrel with sequences from other mammalian species.
A. Alignment of a partial fragment of GRK7 from ground squirrel (GS) with sequence from the eastern chipmunk (CM). Identical amino acids are aligned with vertical bars (|), highly conserved amino acids are aligned with colons (:), and weakly conserved amino acids are aligned with periods (.). Numbers correspond to the amino acid sequence of GS GRK7. B. Alignment of a partial fragment of GS GRK7 with the sequence from the pig. Symbols are as described in Figure 1A. C. Alignment of GRK1 sequences from bovine (Bv), ground squirrel (GS) and pig. Numbers correspond to the amino-acid sequence of bovine GRK1. Sequence comparisons were performed using the computer programs GAP, PILEUP and PRETTY from the Wisconsin Package Version 9.0.
(A) GRK7 (GS) 315 ENVLLDDLGNCRLSDLGLAVEVQDDKPMTQRAGTN 349 ||||||||||||||||||||:||:|||.||||||| GRK7 (CM) ENVLLDDLGNCRLSDLGLAVQVQEDKPITQRAGTN (B) GRK7 (GS) 375 SIYEMVAGRTPFKDFKEKVSKEDLKERTMKDEVAFHHENFTEETKDICRLFLAKK 429 ||||||||||||||:|||:||||||:||:|:|| | |:.|||| |||||||||| GRK7 (Pig) SIYEMVAGRTPFKDYKEKISKEDLKQRTLKEEVRFQHQSFTEEAKDICRLFLAKT GRK7 (GS) 430 PEQRLGSREKADDPRKHPFFQTVNFPRLEAGLVEPPFVPDPSVVYA 475 ||||||||||.|||||| ||.|:||||||||||:|||||||||||| GRK7 (Pig) PEQRLGSREKSDDPRKHHFFKTINFPRLEAGLVDPPFVPDPSVVYA (C) 401 450 GRK1 (Bv) LKQRVLSEPV AYSDKFGQAS RDFCEALLEK DPEKRLGWRD GSCDGLRAHA GRK1 (GS) LKQRVLEEAV TYSDKFSQAS KDFCEALLQK DPEQRLGFRD GTCDGLRASP GRK1 (Pig) LKQRVLEQAV TYPDKFSPAS KDFCEALLQK DPEKRLGFRD GSCDGLRTHP Consensus LKQRVL---V -Y-DKF--AS -DFCEALL-K DPE-RLG-RD G-CDGLR--- 451 498 GRK1 (Bv) LFKDISWRQL EAGMLTPPFI PDSRTVYAKS IQDVGAFSTV KGVAFDNA GRK1 (GS) LFRDMNWRQL EAGMLAPPFI PDSRTVYAKN IQDVGVFSTV RGVVFDKG GRK1 (Pig) LFRDISWRQL EAGMLTPPFV PDSRTVYAKN IQDVGAFSTV KGVAFEKA Consensus LF-D--WRQL EAGML-PPF- PDSRTVYAK- IQDVG-FSTV -GV-F---