Figure 4. Spatiotemporal patterns of IRBP mRNA expression in differentiating photoreceptors and RPE

(A) Schematic representation of stages of IRBP mRNA expression described in Results. Stages were drawn based on representative whole mounts hybridized with IRBP cRNA (such as those in Figure 2). (B) Histograms showing stages of IRBP mRNA expression as a function of embryonic age. To the right of the histograms are other known events in zebrafish retina development that occur (approximately) at the embryonic ages (hours post-fertilization [hpf]) indicated in the histograms [82,97].