Immunostaining for the Col2 expression in the scleras of FDM mouse eyes on day 21 following induction. Col2 was more highly
expressed in the FDM eyes than in the control eyes (Figure 5A,B
). For the α-SMA expression, a greater expression was noted in the scleral and choroid areas of FDM eyes in comparison to
control eyes. (Figure 5C,D
). Some extra-ocular muscle (EOM) tissue existing outside the sclera.