Distribution of MMP/TIMP ratios in cataract versus POAG patients. Stoichiometric ratios were calculated for individual aqueous
humor samples from non-glaucomatous cataract (blue; N=23-24) and POAG (orange; N=16-20) patients. Median ratios and interquartile
ranges are indicated. The ratios for MMP2/TIMP1 (A
), MMP2/TIMP3 (B
), MMP3/TIMP3 (C
), and MMP9/TIMP1 (D
) were significantly different between cataract and glaucoma (p<0.05) patients, as determined using the Mann–Whitney U test.
See Table 3
for the full set of ratios calculated.