Figure 2. Distribution of MMP/TIMP ratios in cataract versus POAG patients. Stoichiometric ratios were calculated for individual aqueous humor samples from non-glaucomatous cataract (blue; N=23-24) and POAG (orange; N=16-20) patients. Median ratios and interquartile ranges are indicated. The ratios for MMP2/TIMP1 (A), MMP2/TIMP3 (B), MMP3/TIMP3 (C), and MMP9/TIMP1 (D) were significantly different between cataract and glaucoma (p<0.05) patients, as determined using the Mann–Whitney U test. See Table 3 for the full set of ratios calculated.