Table 3 of
Briggs, Mol Vis 2015; 21:1162-1172. Table 3 of
Briggs, Mol Vis 2015; 21:1162-1172.
Table 3. Stoichiometric analysis of MMP and TIMP ratios in cataract control versus POAG samples.
| Ratio | Cataract | POAG | p-value | ||||
|---|---|---|---|---|---|---|---|
| Median | Interquartile range | N | Median | Interquartile range | N | ||
| MMP1/TIMP1 | 1.28×10−3 | 8.68×10−4-2.07×10−3 | 23 | 1.20×10−3 | 6.17×10−4-1.96×10−3 | 16 | 0.353 |
| MMP1/TIMP2 | 6.25×10−4 | 4.65×10−4-1.09×10−3 | 23 | 5.88×10−4 | 3.78×10−4-1.22×10−3 | 18 | 0.857 |
| MMP1/TIMP3 | 2.46×10−3 | 1.57×10−3-3.40×10−3 | 23 | 2.69×10−3 | 1.58×10−3-1.47×10−2 | 19 | 0.193 |
| MMP1/TIMP4 | 0.24 | 0.18–0.34 | 15 | 0.33 | 0.22–0.65 | 16 | 0.108 |
| MMP2/TIMP1 | 0.74 | 0.69–1.04 | 24 | 0.64 | 0.46–0.77 | 16 | 0.007 |
| MMP2/TIMP2 | 0.40 | 0.33–0.46 | 24 | 0.35 | 0.30–0.41 | 18 | 0.137 |
| MMP2/TIMP3 | 1.32 | 1.06–1.88 | 24 | 2.01 | 1.48–2.29 | 19 | 0.045 |
| MMP2/TIMP4 | 155.10 | 133.20–170.50 | 15 | 144.10 | 126.80–167.00 | 16 | 0.245 |
| MMP3/TIMP1 | 2.40×10−2 | 1.66×10−2-3.97×10−2 | 23 | 2.52×10−2 | 1.27×10−2-2.91×10−2 | 17 | 0.492 |
| MMP3/TIMP2 | 1.09×10−2 | 9.16×10−3-2.31×10−2 | 23 | 1.53×10−2 | 9.50×10−3-2.56×10−2 | 19 | 0.528 |
| MMP3/TIMP3 | 4.26×10−2 | 3.04×10−2-8.22×10−2 | 23 | 7.10×10−2 | 4.29×10−2-2.24×10−1 | 20 | 0.032 |
| MMP3/TIMP4 | 4.68 | 3.70–7.60 | 15 | 7.26 | 4.04–13.65 | 16 | 0.354 |
| MMP9/TIMP1 | 8.55×10−3 | 4.91×10−3-1.25×10−2 | 24 | 4.64×10−3 | 2.20×10−3-9.11×10−3 | 16 | 0.005 |
| MMP9/TIMP2 | 4.10×10−3 | 2.46×10−3-6.55×10−3 | 24 | 2.70×10−3 | 1.74×10−3-4.70×10−3 | 18 | 0.124 |
| MMP9/TIMP3 | 1.45×10−2 | 8.05×10−3-2.88×10−2 | 24 | 1.42×10−2 | 7.96×10−3-2.74×10−2 | 19 | 0.631 |
| MMP9/TIMP4 | 1.47 | 0.69–2.55 | 15 | 1.17 | 0.60–1.99 | 16 | 0.397 |