Figure 4. Full-field electroretinography (ffERG) performed at the age of 16 and six years later in a female carrier of
RPGR ORF15 X-linked retinitis pigmentosa. At the age of 22, ffERG was performed twice: after 30 min and 6 h of dark adaptation,
respectively. Compared to the ffERG at age 16, rod response was reduced by 28% at the age of 22. The combined rod-cone response
a wave (resulting from activity of the photoreceptors) and b wave (resulting from activity of the bipolar and Muller cells)
were reduced by 39% and 17%, respectively. Under photopic conditions, single flash cone response was reduced by about 41%
and 30-Hz flicker response by 36%. No significant changes were recorded after the 6-h dark adaptation. The figure corresponds
to
Table 2. cd.s/m
2=candela seconds per square meter. µV=microvolts. ms=milliseconds.