Figure 8 of Poliakov, Mol Vis 2014; 20:285-300.


Figure 8. A2E is present in ARPE-19 lysosomal fractions. Matrix-assisted laser desorption-ionization time-of-flight (MALDI-TOF) mass spectrometric analysis of lysosomal fraction 8 (see Figure 7A) isolated from multiple 1 µM A2E-treated ARPE-19 cells show the presence of A2E (m/z 592) and a minor oxidation product (m/z 608) consistent with furan-A2E. Results shown are representative of three separate experiments.