Table 1 of Guo, Mol Vis 2014; 20:1643-1659.


Table 1. Genes examined, divided into functional categories, with cellular location of the protein encoded by the gene.

Gene symbol Protein name Location
Signaling − Cell surface
ACVRL1 Activin A receptor 2-like 1 Cell surface
FGFR2 FGF receptor 2 Cell surface
NPR3 Atrial natriuretic peptide receptor 3 Cell surface
SDC2 Syndecan 2 Cell surface
TGFBR3 TGFβ receptor III Cell surface
TRPV4 Transient receptor potential cation channel V4 Cell surface
UNC5B Netrin receptor UNC5B Cell surface
EFNA1 Ephrin A1 Cell surface
Signaling − Cytoskeleton related
ANXA1 Annexin A1 Cell surface
ANXA2 Annexin A2 Cell surface
CAPN2 Calpain 2 Cell surface
CAPNS1 Calpain small subunit 1 Cell surface
GJA1 Connexin 43 Cell surface
ACTA2 Smooth muscle actin Intracellular
NGEF Neuronal guanine nucleotide exchange factor Intracellular
Signaling − Transcription regulators
HIF1A Hypoxia-inducible factor 1α Intracellular
RARB Retinoic acid receptor β Intracellular
RXRB Retinoid X receptor β Intracellular
VDR Vitamin D receptor Intracellular
Signaling − Secreted
ANGPTL7 Angiopoietin-related protein 7 Extracellular
IGF1 Insulin-like growth factor 1 Extracellular
IGF2 Insulin-like growth factor 2 Extracellular
IL18 Interleukin 18 Extracellular
PENK Proenkephalin A Extracellular
TGFB1 Transforming growth factor β1 Extracellular
TGFB2 Transforming growth factor β2 Extracellular
TGFBI TGFβ-induced protein Extracellular
Signaling − Matricellular
CTGF Connective tissue growth factor Extracellular
CYR61 Protein CYR61 Extracellular
FBLN1 Fibulin 1 Extracellular
NOV Protein NOV homolog Extracellular
SPARC Secreted protein acidic and rich in cysteine Extracellular
SPP1 Osteopontin Extracellular
THBS1 Thrombospondin 1 Extracellular
THBS2 Thrombospondin 2 Extracellular
TNC Tenascin C Extracellular
WISP1 WNT1 inducible signaling pathway protein 1 Extracellular
MPs / TIMPs
ADAMTS5 ADAM metallopeptidase with thrombospondin motif, 5 Extracellular
MMP2 Matrix metallopeptidase 2 Extracellular
MMP14 Matrix metallopeptidase 14 Cell surface
TIMP1 TIMP metallopeptidase inhibitor 1 Extracellular
TIMP2 TIMP metallopeptidase inhibitor 2 Extracellular
TIMP3 TIMP metallopeptidase inhibitor 3 Extracellular