Figure 3 of Uren, Mol Vis 2014; 20:1612-1628.


Figure 3. Significantly enriched biologic processes and KEGG pathways among differentially expressed genes. A: Significantly enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and biologic processes among genes that show increased relative expression and their corrected p value are shown. For each pathway or process, the genes present in it are listed, and the strength of the fold-change for each gene is shown. B: The alternative, lectin, and classical pathways of the complement cascade (top enriched KEGG pathway among genes with increased relative expression). Highlighted are all genes showing significant differential expression (in all cases, increased relative mRNA levels in rd10 retina versus wild-type retina). C: Significantly enriched biologic processes among those genes with a significant decrease in their relative expression, and the corrected p values for each term.