Table 1 of Ma, Mol Vis 2014; 20:1434-1442.

Table 1. Baseline characteristics and methodological quality of all included studies.

First author Year Country Ethnicity Source Sample size Gender (M/F) Age (years) Genotyping
method HWE test NOS
score
Case Control Case Control Case Control (p value)
Nakata et al. [5] 2011 Japan Asian HB 401 336 287/114 142/194 77.4±8.4 74.2±8.4 TaqMan assay 0.59 8
PB 401 1194 287/114 493/701 77.4±8.4 50.3±15.9
Carter et al. [4] 2011 UK Caucasian PB 94 95 26/68 32/63 51~94 55~89 TaqMan assay 0.23 7
Lu et al. [11] 2010 China Asian PB 272 285 126/146 132/153 68.2±9.8 68.4±7.2 TaqMan assay 0.49 8
Lee et al. [16] 2010 USA Caucasian PB 556 256 177/379 116/140 79 70 MassArray 0.29 8
Park et al. [17] 2009 USA Caucasian HB 476 310 169/307 141/169 76.9±9.6 69.5±8.2 TaqMan assay 0.44 8
Allikmets et al. [15] 2009 UK Caucasian PB 4881 2842 - - - - TaqMan assay 0.55 7
Ennis et al. [6] 2008 UK Caucasian PB 479 479 181/298 232/247 77.9±8.8 70.6±9.4 TaqMan assay 0.85 8

M=male; F=female; SNP=single nucleotide polymorphism; HWE=Hardy–Weinberg equilibrium; NOS=Newcastle-Ottawa Scale; HB=hospital-based; PB=population-based.

Ma, Mol Vis 2014; 20:1434-1442. http://www.molvis.org/molvis/v20/1434

©2014 Molecular Vision http://www.molvis.org/molvis/

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