Molecular Vision: Bollinger, Mol Vis 2012; 18:2001-2011. Table 2

Table 2. Proteins elevated in dexamethasone-treated TM cells.

SwissProt accession	Protein	Subcellular source	Sample frequency total=4	Mean protein ratio	SEM	p-value
Cytoskeletal/cell-cell/cell-matrix Interactions
O94875	Sorbin and SH3 domain-containing protein 2	B	4	3.06*	0.10	0.001
Q0ZGT2	Nexilin	B	4	2.03*	0.17	0.026
Q13740	CD166 antigen	C	4	1.99*	0.12	0.011
O75369	Filamin-B	B	4	1.64*	0.11	0.020
Q15942	Zyxin	BD	4	1.38	0.04	0.005
Q13418	Integrin-linked protein kinase	C	4	1.36	0.09	0.037
Q8WX93	Palladin	B	4	1.31	0.08	0.044
P35613	Basigin	C	4	1.29	0.04	0.007
Q6NZI2	Polymerase I and transcript release factor	BC	4	1.26	0.05	0.020
Carbohydrate Metabolism
P37837	Transaldolase	B	4	1.43	0.08	0.019
P52209	6-phosphogluconate dehydrogenase, decarboxylating	B	4	1.35	0.07	0.019
P11413	Glucose-6-phosphate 1-dehydrogenase	B	3	1.30	0.03	0.015
P60174	Triosephosphate isomerase	B	4	1.26	0.06	0.031
Mitochondrial Metabolism
Q9Y6N5	Sulfide:quinone oxidoreductase	E	4	1.81*	0.06	0.002
Q9UIJ7	GTP:AMP phosphotransferase	E	4	1.56*	0.07	0.007
P42765	3-ketoacyl-CoA thiolase	E	4	1.39	0.06	0.011
Q13510	Acid ceramidase	B	3	1.35	0.05	0.031
P30049	ATP synthase subunit delta	CE	4	1.34	0.07	0.023
P61604	10 kDa heat shock protein	E	4	1.33	0.08	0.042
P36957	Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex	E	3	1.25	0.03	0.014

Adjusted mean protein ratios (DEX-treated/Control), standard error of the mean (SEM), p-values and subcellular source are shown for abundant proteins (from Appendix 5). Abundant proteins exhibited mean ratios at least 1SD above the mean and p-values <0.05 (see Figure 2). All proteins were quantified in ≥3 TM cell samples (median ratio=0.99, mean=1.00, SD=0.22, n=341). Asterisks denote ratios at least 2 SD above the mean. Protein subcellular source from the Swiss Protein database: A, secreted; B, cytoplasmic; C, membrane; D, nuclear; E, mitochondrial.