Figure 2. SLAT/Def6 KO mice are inferior to their WT controls in their cellular response to the immunizing antigens. A: Proliferative assay of a representative experiment; similar data were obtained in 2 other repeated experiments. IRBP was added at the indicated concentrations (μg/ml). PPD was added at 5 μg/ml. * p<0.05, **p<0.005. B: Levels of IL-17 and IFN-γ secreted by lymph node cells of SLAT/Def6 KO mice cultured with IRBP at 10 μg/ml. Data of two experiments, with supernatants collected on day 2 or 4 of culture. ns=not significant; *p<0.05.