Figure 1 of Vistica, Mol Vis 2012; 18:1858-1864.


Figure 1. SLAT/Def6 deficient mice are inferior to their WT controls in developing EAU. A: Disease scores of individual mice of the two mouse lines. Horizontal lines are mean ±SEM. A summary of repeated experiments comparing the response in mice of the two lines. ** p<0.005. B: Sections of representative eyes of the two groups. The changes in the eye of the control mouse are markedly more severe and mainly include infiltration of inflammatory cells in various ocular tissues, as well as retinal folding and loss of photoreceptor cells (score: 2+). Only minor infiltration is seen in the SLAT/Def6 deficient mouse eye (score: 0.5).