Figure 5. Interleukin-17A and
interferon-γ production in corneas and serum during the first
two days after infection or sham treatment. At 6, 12, 24, and 48
h post infection, the animals were sacrificed and the
interleukin (IL)17A and interferon (IFN)γ in both serum and
corneas were measured as described in the legend for
Figure 4.
Please note that no sham-infected corneas produced detectable
IL17A at any time point in either strains. However, naïve mice
of both strains had detectable baseline IFNγ production, and
while sham treatment did not change the baseline level,
Candida
albicans keratitis (CaK) induction decreased IFNγ
production to an undetectable level in the early phase.
A:
IL17 contents in corneas.
B: IL17 concentrations in
serum.
C: IFNγ contents in corneas.
D: IFNγ
concentrations in serum. * p<0.05 (n=3) for comparison in
these two strains.