Figure 1. Small-angle X-ray scatter patterns (represented by circles) were collected at 1 mm intervals over each guinea pig cornea. Twelve measurements of fibril diameter, fibril separation distance, and D-periodicity from the central cornea were used (white circles) to produce weighted averages for each treatment group (Table 1). Measurements across the horizontal meridian of each cornea (circles containing a line) were averaged within treatment groups to show limbus-to-limbus changes in fibril separation distance and fibril diameter (Figure 3). The position of the limbus is shown as a dashed black line. A scleral suture at the 12 o’clock position ensured that in vivo corneal orientation was maintained during data collection.