Comparisons of internal nuclei and fragment retention (gray columns) and opacity by slit lamp (dashed lines). The grades are
for old individuals (80%–100% of maximum lifespan) from 8 strains from 5 species. C57BL/6 mice for nuclear retention grades:
9 eyes from 9×28 month-old mice; for opacity the average of 8 eyes (from 8 mice) at 24 months and 8 eyes (from8 mice) at 32
months. For the DBA mice: 8 eyes from 4×24 month old DBA mice/ For CBA mice: 7 eyes from 4×27 month-old CBA mice. Rats: 4
eyes from 4×31 month-old BNF1 rats, 8 eyes from 4×31 month-old Brown Norway rats (BN). Dogs: 10 eyes from 7 old dogs from
9 to 17 years, mean age=12 years, opacity in dogs not regularly noted at supplier site, although one noted to have cataract.
Monkeys:16 eyes from 15 old female and male rhesus (19–38 years), mean=24 years opacity not regularly checked, but 2 individuals
noted to have cataracts. Humans: 10 eyes from 7 elderly male and female human autopsies (64–88 years, mean=80 years). Opacity
in humans was not regularly checked, but one individual was noted to have bilateral cataracts. Other details are as in the
legend to Figure 1
. For species life spans see Methods references.