Appendix 1. Pedigrees of remaining 27 Polish families with high grade myopia. Filled symbols: individuals with high myopia; open symbols: unaffected individuals; symbols with question mark: individuals with unknown disease status. To access the data, click or select the words “Appendix 1.” This will initiate the download of a compressed (pdf) archive that contains the file.

Appendix 2. Detailed clinical findings in family HM-32. To access the data, click or select the words “Appendix 2.” This will initiate the download of a Microsoft Word (.doc) file that contains the Table.

Appendix 3. Statistically significant differences in spherical refractive error (SPH), spherical equivalent refractive error (SE), and axial length (AL) between studied groups. To access the data, click or select the words “Appendix 3.” This will initiate the download of a Microsoft Word (.doc) file that contains the Table.

Appendix 4. Detailed linkage analysis results of three distinct loci identified on chromosome 7p22.1–7p21.3, 7p12.3- 7p11.2, and 12p13.1–12p12.2, respectively (A-C) for Family HM-32. To access the data, click or select the words “Appendix 4.” This will initiate the download of a Microsoft Word (.doc) file that contains the Table.

Appendix 5. Linkage analysis for chromosome 7p22.1–7p21.1, 7p13–7p11.2, and 12p13.1–12p12.1 loci. For each locus 1 SPN per 0.5 cM, 1.0 cM, 1.5 cM, and 2 cM was selected to prune out the LD. PL – parametric linkage, NPL – non-parametric linkage. To access the data, click or select the words “Appendix 5.” This will initiate the download of a Microsoft Word (.doc) file that contains the Table.