Table 3 of Yeghiazaryan, Mol Vis 2009; 15:2339-2348. Table 3 of Yeghiazaryan, Mol Vis 2009; 15:2339-2348.
Table 3. Differentially expressed genes versus controls.
| Double-spot
position in “EA”-image exp. difference versus control |
Name of gene as given in “AtlasTM Human Cardiovascular Array” |
GenBank accession |
SwissProt accession |
Gene/Protein classification |
|---|---|---|---|---|
| BLOCK A | ||||
| A7d increased | P2Y purinoceptor 7 (P2Y7); leukotriene B4 receptor; Chemoattractant receptor-like1 (CMKRL1) | U41070 | Q15722; Q13305; Q92641 | Other Receptors (by Ligands) G Protein-Coupled Receptors |
| A7e increased | Retinoic acid receptor gamma 1 (RAR-gamma 1; RARG) | M24857; M38258; M57707; M32074 | P13631 | Transcription Activator & Repressors; Hormone Receptors; Nuclear Receptors |
| BLOCK B | ||||
| B1n increased | Androgen receptor coactivator 70-kDa subunit (ARA70) | L49399 | Q13772 | Transcription Activator & Repressors |
| B4c increased | G protein-activated inward potassium channel 4 (GIRK4); heart K+/ATP channel (KATP1); cardiac inward rectifyer (CIR); KIR3.4 | U39195 | P48544; Q92807 | Voltage-gated Ion Channels |
| B4d increased | Sodium/calcium exchanger 1 precursor; Na+/Ca2+-exchange protein 1 | M91368 | P32418 | Symporters & Antiporters |
| B4e increased | Multidrug resistance protein 3 (MDR3); P-Glycoprotein 3 (PGY3) | M23234 | P21439 | Drug-Resistance Proteins; Xenobic Transporters |
| B5f increased | Endothelial nitric oxide synthase (EC-NOS) | M93718 | P29474 | Other Metabolism Enzymes; Other Intracellular Transducers, Effectors & Modulators |
| B6d increased | Intercellular adhesion molecule 1 precursor (ICAM1); major group rhinovirus receptor; CD54 antigen | J03132 | P05362 | Matrix Adhesion Receptors |
| 7g increased | Calcium & integrin-binding protein (CIB) | U85611 | Q99828 | Calcium-Binding Proteins |
| 1g increased | Cadherin 7 (CDH7) | AF047826 | O60574 | Cell Surface Antigens; Cell-Cell Adhesion Receptors |
| 1h increased | Intestinal peptide-associated transporter 1 (HPT1) | U07969 | Q12864 | Other Cell Adhesion Proteins; Other Cell Adhesion Proteins; Other Facilitated Diffusion Proteins |
| 2i increased | GAP junction alpha-5 protein | L34954 | P36382 | Cell-Cell Adhesion Receptors; Other Membrane Channels & Transporters |
| 3m increased | Integrin beta 2 (ITGB2); cell surface adhesion glycoprotiens LFA-1/CR3/p150, 95 beta subunit precursor; CD18 antigen; Complement receptor C3 beta subunit | M15395 | P05107; Q16418 | Cell-Cell Adhesion Receptors |
| 1m increased | Cardiac LIM domain protein; muscle LIM protein; cystein-rich protein 3 (CRP3); LIM-only protein 4 | U49837 | P50461 | Basic Transcription Factors; Other Transcription Proteins; DNA Synthesis, Recombination & Repair Proteins |
| 1n increased | Cardiotrophin-1 (CT1) | U43030 | Q16619 | Growth Factors, Cytokines & Chemokines |
| 2n increased | Matrix metalloproteinase 16 (MMP-16) | D83646 | P51512 | Chromatin Proteins; Metalloproteinases |
| 4a increased | TIMP-3 | U14394 | P35625 | Extracellular Matrix Proteins; Proteinase Inhibitor |
| 4b increased | TIMP-4 | U76456 | Q99727 | Extracellular Matrix Proteins; Proteinase Inhibitor |
| 4d increased | Sterol regulatory element-binding transcription factor 1 | U00968 | P36956 | Basic Transcription Factors; Other Apoptosis-Associated Proteins |
| 4e increased | Sterol regulatory element-binding transcription factor 2 | U02031 | Q12772 | Basic Transcription Factors; Other Apoptosis-Associated Proteins |
| 5h increased | Rab geranylgeranyl transferase bety subunit | Y08201 | P53611; Q92697 | Trafficking & Targeting Proteins; Protein Modification Enzymes; GTP/GDP Exchangers & GTPase Activity Modulators |
| 6m decreased | Muscle-specific Dnase I-like precursor (Dnase 1L1; DNL 1L); Dnase X | X90392; L40817; U06846 | P49184 | DNA Synthesis, Recombination & Repair Proteins; Apoptosis-Associated Proteins |
| 1b increased | Lanosterol synthase (LSS); oxidosqualene lanosterol cyclase (OSC) | D63807 | P48449 | Complex Lipid Metabolism |
| 3n increased | NADPH-cytochrome p450 reductase | S90469 | Q16455; P16435 | Xenobic Metabolism |
| 4g increased | Steroid 5 alpha reductase 1 (SRD5A1); 3-oxo-5-alpha steroid 4 dehydrogenase 1 | M32313; M68886 | P18405 | Complex Lipid Metabolism |
| 4h increased | Steroid 5-alpha reductase 2 (SRD5A2); 3-oxo-5-alpha steroid 4 dehydrogenase 2 | M74047 | P31213 | Complex Lipid Metabolism |
| 2d increased | Pregnane X receptor (PXR) | AF061056 | O75469 | Hormone Receptors; Nuclear Receptors |
| F2e increased | Estrogen-related receptor gamma | AF058291 | O75454 | Hormone Receptors; Nuclear Receptors |
| F2f increased | Nuclear receptor subfamily 4 group A member 2 (NR4A2); nuclear receptor-related protein 1 (NURR1); transcriptionally inducuble nuclear receptor (TINUR); NOT | X75918 | P43354 | Hormone Receptors; Nuclear Receptors; Transcription Activators & Repressors |
| 2i increased | Orphan nuclear receptor TR4; nuclear receptor subfamily 2 group c member 2 (NR2C2); TAK1 | U10990 | P55092; P49116 | Orphan Receptors; Nuclear Receptors; Transcription Activators & Repressors |
| 3a increased | RAR-related orphan receptor C | U16997 | P51449 | Orphan Receptors; Nuclear Receptors; Transcription Activators & Repressors |
| 3e increased | LX receptor alpha (LXR alpha) | U22662 | Q13133 | Orphan Receptors |
| 3i increased | Platelet-activating factor acetylhydrolase IB alpha subunit | L13387 | P43034 | Other Metabolism Enzymes |
| 7c increased | Myocyte-specific enhancer factor 2A (MEF2A); serum response factor-like protein 1 | X68505 | Q02078; Q14223; Q14224 | Basic Transcription Factors |