Figure 9. Retinal ganglion cells correlation with Fbxl20. x-axis units are in 1000s relative to the mean value of about 58,000 cells. y-axis units are log2 signal intensity. Fbxl20 is physically linked to the Nnc1 locus on Chr 11. Despite the strong genetic and statistical association, this gene is unlikely to cause variation in cell number (see text). The effect is likely to be due to linkage disequilibrium. How to generate a correlation graph between a probe set and a phenotype: Step 1. With the descriptors set as “Choose Species=Mouse, Group=BXD, Type=Eye mRNA, Database=Eye M430v2 (Sep08) RMA,” search the ANY search box for the gene Fbxl20 (1445575_at). Place a check in the box by the 1445575_at probe and click the Add to Collection button. Step 2. Return to the search page and change “Type” to Phenotypes, and “Database” to BXD Published Phenotypes. In the ANY box, search “Retinal Ganglion Cell Number” or 10650. Place a check in the box next to “recordID/10650 – Retinal Ganglion cell number” and click 'Add to Collection' button. Step 3. Follow the instructions from Figure 6 to arrive at the correlation scatter plot shown.