Table 3 of
Abu-Amero, Mol Vis 2008;
14:29-36.Table 3 of
Abu-Amero, Mol Vis 2008;
14:29-36.
Table 3. mtDNA and mitochondrial respiratory changes in PEG patients
PEG patients organized according to characteristics of "Nucleotide Change(s)" from Table 2 for each patient. Patients 1-17 had no noteworthy mtDNA changes (see Methods), while patients 18-26 had NS mtDNA changes not thought to be pathologic, and patients 27-29 had NS mtDNA changes thought likely to be pathologic (see Methods). Relative mtDNA Content=ratio of ND1 to β-actin (see Methods). MRA=Mitochondrial Respiratory Activity (see Methods).
Relative
Nucleotide mtDNA
Patient change (s) content MRA
------- ----------- -------- ----
1 None 1.20 21.6
2 None 1.35 21.8
3 None 1.20 21.9
4 None 1.90 19.6
5 None 1.40 20.4
6 None 1.30 21.6
7 None 1.20 21.6
8 None 1.10 22.5
9 None 1.20 20.5
10 None 1.10 19.8
11 None 1.30 18.9
12 None 1.50 21.9
13 None 1.30 21.4
14 None 0.92 21.9
15 None 0.81 22.5
16 None 1.10 21.4
17 None 1.08 19.8
18 5182 0.80 21.4
19 4363 1.20 20.4
20 4385, 12841 1.20 21.5
21 9438 1.60 20.8
22 5843 1.20 20.2
23 9103, 13813 0.83 21.9
24 9103 0.82 21.8
25 11337 1.20 20.4
26 4385, 6546 1.09 18.6
27 3833 0.85 19.8
28 7877 1.20 20.8
29 4648 1.40 21.4
|