Molecular Vision: Sun, Mol Vis 2008; 14:2237-2262. Table 2

Table 2. Description of the statistically significant clusters represented in Figure 2.

Description	E7 Clusters*	E14 Clusters*
Affected only by serum	13, 39	13, 39
Affected only by rcSF3	None	None
Serum and rcSF3 oppose one another	7, 14, 18, 34, 35, 38	14, 18, 34, 38
Serum and rcSF3 reinforce one another	0, 8, 49	0, 8, 10, 49
Serum and rcSF3 modulate one another	2, 5, 42	2, 5, 10, 47
Serum and rcSF3 substitute for one another	None	12
Gene expression increases with increasing TER	42	None
Gene expression decreases with increasing TER	None	None

Cluster analysis showed that some genes were affected solely by serum, but none were affected by only rcSF3. For most genes there was an interaction between these two stimuli. Serum and rcSF3 could act synergistically to induce or repress gene expression. There were also examples where one opposed the action of the other. For a small subset of genes, the effects of serum and rcSF3 on expression paralleled the effects that they had on the TER. The asterisk represents the cluster numbers correspond to Figure 2.