Table 2 of Shiels, Mol Vis 2008; 14:2042-2055.

Table 2. SNP disease haplotype for the cataract-linked interval on chromosome 1p.

 
SNP		   Disease
allele		   Distance from 1-ptel
  Mb   cM
rs707455*   C   7.75   13.68
rs8627   A   8.34   14.21
rs1473420   A   8.54   14.48
rs916380   A   9.26   15.43
rs630075   T   9.29   15.47
rs6677649   A   9.67   16.64
rs2119508   G   9.78   16.66
rs2379107   A   9.83   16.67
rs7528979   C   10.02   16.70
rs6541085   A   10.21   16.73
rs912962   T   10.27   16.74
rs649101   T   10.41   16.77
rs2506887   A   10.51   16.78
rs481453   T   10.60   16.99
rs488834   T   10.69   17.33
rs7555879   G   10.81   17.76
rs2273348   C   11.00   18.43
rs4846012   G   11.48   20.07
rs2817594   A   11.54   20.24
rs3818157   G   11.95   21.26
rs235256   C   12.22   21.31
rs761162   A   14.24   24.73
rs1416633   C   14.36   24.96
rs7531416   A   14.62   25.58
rs3927648   A   14.74   25.86
rs1883661   A   14.88   26.20
rs4357518   A   14.95   26.46
rs3845596   T   15.06   26.91
rs7515649   C   15.31   27.49
rs488595   G   15.56   27.95
rs1007150   T   16.49   29.61
rs761423   G   17.17   30.83
rs1005753   A   17.32   31.08
rs3766306   T   17.84   32.02
rs1578215   G   17.99   32.31
rs477558**   G   18.09   32.53

The disease associated allele is shown for each SNP in the cataract interval, which spans ~10 megabases (Mb) or ~19 centi-Morgans (cM). The asterisk denotes critical recombinant individual III:8 in family Mu (Figure 1A) with genotype T/T at rs707455. The double asterisk denotes critical recombinant individual IV:6 (Figure 1A) with genotype A/A at rs477558.

Shiels, Mol Vis 2008; 14:2042-2055. http://www.molvis.org/molvis/v14/a241

©2008 Molecular Vision http://www.molvis.org/molvis/

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