Molecular Vision: Demos, Mol Vis 2008; 14:1639-1649. Table 1

Table 1. Genes corresponding to human disease loci identified by being either commonly up- or down-regulated in three, independent mouse models of photoreceptor dystrophy.

Affymetrix gene ID	Gene name	Gene symbol	Mouse transcript ID	Human ortholog NM	Ortholog chromosomal location	Retinal degeneration locus
160901_at	FBJ osteosarcoma oncogene	Fos	NM_010234	NM_001040059	14q24.3	LCA3
97540_f_at	histocompatibility 2, D region locus 1	H2-D1	NM_001025208	NM_005516	6p21.3	TULP1/RP14
101923_at	phospholipase A2 group VII (platelet-activating factor acetylhydrolase, plasma)	*Pla2g7*	NM_013737	NM_005084	6p21.2-p12	RDS/RP7; GUCA1A, GUCA1B; BCMAD
98549_at	vitronectin	Vtn	NM_011707	NM_000638	17q11	UNC119/HRG4
98579_at	early growth response 1	*Egr1*	NM_007913	NM_001964	5q31.1	BSMD, PDE6A
92223_at	complement component 1, q subcomponent, C chain	C1qc	NM_007574	NM_172369	1p36.11	NRL/RP27
96020_at	complement component 1, q subcomponent, beta polypeptide	*C1qb*	NM_009777	NM_000491	1p36.3-p34.1	LCA9, RP32
103033_at	complement component 4 (within H-2S)	C4	NM_009780	NM_000592	6p21.3	TULP1/RP14
98472_at	histocompatibility 2, T region locus 23	H2-T23	NM_010398	NM_005252	6p21.3	TULP1/RP14
94701_at	phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide	Pde6b	NM_008806	NM_000283	4p16.3	PDE6B/CSNB3, MCDR2
102612_at	neural retina leucine zipper gene	Nrl	NM_015810	NM_006177	14q11.1-q11.2	NRL/RP27
160894_at	CCAAT/enhancer binding protein (C/EBP), delta	*Cebpd*	NM_007679	NM_005195	8p11.2-p11.1	CORD9
94854_g_at	guanine nucleotide binding protein, beta 1	*Gnb1*	NM_008142	NM_002074	1p36.3-p34.1	LCA9, RP32, RD4
93120_f_at	histocompatibility 2, K region	H2-K	NM_001001892	NM_002127	6p21.3	TULP1, RP14
98562_at	complement component 1, q subcomponent, alpha polypeptide	*C1qa*	NM_007572	NM_015991	1p36.3-p34.1	LCA9, RP32
95974_at	guanylate nucleotide binding protein 1	Gbp1	NM_008142	NM_002074	1p36.3-p34.1	ABCA4
103202_at	guanylate nucleotide binding protein 3	Gbp3	NM_018734	NM_133263	1p22.2	ABCA4
103634_at	interferon dependent positive acting transcription factor 3 gamma	Isgf3g	NM_008394	NM_006084	14q11.2	NRL/RP27
104669_at	interferon regulatory factor 7	Irf7	NM_016850	NM_004030	11p15.5	TEAD1/AA/TCF13/ TEF1
99608_at	peroxiredoxin 2	Prdx2	NM_011563	NM_005809	19p13.2	R9AP

The highlighted gene symbols (column 3) represent the mapped, but unsolved loci (column 7), the remaining genes localize to loci that have already been solved. The genes are documented with respect to the mouse gene name, symbol and mouse transcript ID (columns 2-4) and their human ortholog (column 5). Column 6 provides information about the chromosomal location of the human ortholog; column 7 lists the name(s) of the loci. Please note that in some entries in the locus column, there are multiple names given, meaning that more than one trait resides in that chromosomal location; however these may or may not be related. Column 1, the Affymetrix Gene ID; and column 3, the gene symbol; represent the common denominators for all Tables in the manuscript (Table 1 and Table 2) and Appendix 1 and Appendix 2.