Table 5 of Lupien, Mol Vis 2007; 13:1828-1841.


Table 5. Association between chromosomal location of the clones obtained from the human Müller cells subtracted cDNA library with visual pathologies

The chromosomal location of some of the human ESTs and novel Müller cells cDNAs identified in Table 3 and Table 4 correspond to known retinal pathology loci on the RetNet website.

 Clones from
  human Müller     Accession                                                Known
cells subtracted    number                                                 candidate   Chromosomal
 cDNA library      (GenBank)                Visual pathology                 gene       location
----------------   ---------   -----------------------------------------   ---------   -----------
HMC-E42            AL109613    Recessive Stargardt disease, recessive      ABCA4       1p22.1
                               cone-rod dystrophy
HMC-F35            BF228449    Recessive retinitis pigmentosa, Leber       CFH         1q31.3
                               congenital amaurosis
HMC-Clone 92       AB07014     Dominant optic atrophy                      OPA1        3q29
HMC-Clone 106      AY063513    Recessive Wolfram syndrome                              4q22.3
HMC-Clone 142      AC108067    Recessive Wolfram syndrome                              4q22.3
HMC-C20            CK726461    Dominant Wagner disease                                 5q13.2
HMC-D22            CB120649    Dominant cone dystrophy                     GUCA1A      6p21.1
HMC-B33            CK726459    Leber congenital amaurosis                              6q15
HMC-C21            CF269880    Leber congenital amaurosis                              6q15
HMC-Clone 50       AC093844    Dominant cone dystrophy                                 6q25.1
HMC-Clone 65       CK726468    Dominant cone dystrophy                                 6q25.3
HMC-E8             CK726474    Recessive Refsum disease                    PEX1        7q21.2
HMC-B18            CK726458    Recessive cone-rod dystrophy                            8p11.22
HMC-B40            CK726460    Dominant retinitis pigmentosa               TTPA        8q12.3
HMC-F15            BF228449    Recessive Refsum disease, recessive optic   PXMP3       8q21.13
                               atrophy
HMC-Clone 136      CK726464    Recessive Refsum disease, recessive optic   PXMP3       8q21.13
                               atrophy
HMC-G14            CB121147    Recessive Refsum disease, recessive optic   PXMP3       8q21.13
                               atrophy
HMC-Clone 133      BQ783364    Recessive Usher syndrome, type 1f                       10q21.1
HMC-C46            CK726463    Recessive Bardet-Biedl syndrome             MKKS        20p12.2
HMC-Clone 42       CF269892    X-linked retinitis pigmentosa                           Xp11.3
HMC-F2             AA878056    Retinitis pigmentosa with myopathy                      Xq21.1

Lupien, Mol Vis 2007; 13:1828-1841 <http://www.molvis.org/molvis/v13/a204/>
©2007 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535