Table 3 of Lupien, Mol Vis 2007; 13:1828-1841.


Table 3. Matching of cDNA from human Müller cells to known genes

NCBI, UCSC, and EMBL databases were used to match cDNA from human Müller cells to known genes.

                                                                            Genebank
                                                Chromosomal                 accession
    Gene                                         location      Redundancy    number
--------------------------------------------   -------------   ----------   ---------
Cell cycle/proliferation  (1.7%)
Cysteine and glycine-rich protein 2 (CSRP2)    12q21.1                      NM_001321
Myc-induced nuclear antigen (MINA53)           3q11.2                       NM_032778

Cellular metabolism  (7.4%)
Casein kinase-1 gamma-3 (CSNK1G3)              5q23                         NM_004384
Cystathionase (CTH)                            1p31.1                       NM_001902
Dimethylarginine dimethylaminohydrolase        1p22                2        NM_012137
1 (DDAH1)
Meningioma expressed antigen 5 splice          10q24.1-q24.3                NM_012215
variant, hyaluronidase  (MGEA5)
Myotubularin-related protein 2 (MTMR-2)        11q22                        NM_016156
Phospholipase A2 group XII (PLA2G12)           4q25                         NM_030821
Similar to procollagen-lysine                  3q23-q24                     NM_000935
2-oxoglutarate-5-dioxygenase (PLOD2)
Thioredoxin reductase 1 (TXNRD1)               12q23-q24.1                  NM_003330

Cell surface markers/cell adhesion  (5.0%)
Bullous pemphigoid antigen 1 (BPAG1)           6p12-p11            3        NM_001723
Cadherin 11 type 2 (CDH11)                     16q22.1                      NM_001797
Integrin beta-like 1 (ITGBL1)                  13q33                        NM_004791
Thymosin beta 4 (TMSB4X)                       Xq21.3-q22                   NM_021109

Cytoskeleton  (2.5%)
Adducin 3 (ADD3)                               10q24.2-q24.3                NM_016824
Diaphanous protein                             9q21.31                      NM_006729
Dystrophin (DMD)                               Xp21.2                       NM_004018

Extracellular matrix  (4.1%)
Collagen type 1 alpha 2 (COL1A2)               7q22.1                       NM_000089
Collagen type III alpha 1 (COL3A1)             2q31                2        NM_000090
Fibronectin (FN1)                              2q34                2        NM_002026

Immune-related/blood cell proteins/serum  (3.3%)
CD24 antigen                                   6q21                         NM_013230
Coagulation factor VIII associated             Xq28                         NM_90707
protein B
Haplotype                                      11p15.4                      DQ_856317
Immunoglobulin                                 22q11.2                      DQ_87003

Protein processing/trafficking  (9.9%)
Phosphatidylinositol binding clathrin          11q14                        NM_001008660
assembly protein (PICALM)
Proteoglycan 1, secretory granule (PRG1)       10q22.1             7        NM_002727
Serpine-2                                      2q33-q35            3        NM_006216
Start domain containing 4, sterol              5q22.1                       AL_832599
regulated (STARD4)

Signaling molecules/growth factors/receptors  (19.0%)
Bridging integrator 3 (BIN3)                   8p21.3              2        NM_018688
Extracellular sulfatase (SULF1)                8q13.2-q13.3                 NM_015170
Interleukin 6 (IL-6)                           7p21                2        NM_000600
Latent transforming growth factor beta         14q24                        NM_000428
binding protein 2 (LTBP2)
Metabotropic glutamate receptor 1              6q24                         NM_000838
precursor (GRM1)
Multiple endocrine neoplasia (MEN1)            11q13                        NM_000244
Nerve growth factor beta polypeptide           1p13.1                       NM_002506
(NGFB)
Optic atrophy 1 (OPA1)                         3q28-q29                     NM_015560
Protein tyrosine phosphatase (PTP)             9q22.32                      AY_171233
Serine/threonine kinase 3 (STK3)               8q22.2                       NM_006281
Serine/threonine kinase 24 (STK24)             13q31.2-q32.3       8        NM_003576
Similar to amyloid beta A4 precursor           4p14                2        NM_173075
protein binding family(APBB2)
Transferrin                                    3q29                         NM_003234

Transcription/nuclear specific proteins  (5.8%)
C9orf5                                         9q31                         NM_032012
C11orf23                                       11q13                        NM_018312
C14orf31                                       14q22.1                      NM_152330
Chromobox homolog 3 heterochromatin            7p15.2                       NM_007276
like protein 1(CBX3)
Pre B cell leukemia transcription              1q23                         NM_002585
factor 1 (PBX1)
Retinoblastoma binding protein 4 (RBBP4)       1p35.1                       NM_005610
Zinc finger protein 258 (ZNF-258)              1p34.2                       NM_007167

Translation/protein synthesis  (22.3%)
Eukaryotic translation elongation              6q14.1             18        NM_001402
factor-1 alpha-1 (EEF1A1)
Glucan (1,4-alpha) branching                   3p12.3              2        NM_000158
enzyme 1 (GBE1)
Proprotein convertase subtilisin/kexin         9q21.3                       NM_006200
type 5 (PCSK5)
Translation initiation factor-3                20p12.1             6        U_78525


Miscellaneous  (3.3%)
Brain specific angiogenesis                    6q12                         NM_001704
inhibitor 3 (BAI3)
Humanin (HN1)                                  3q11.2                       AY_029066
Lung cancer metastasis related                 11q12.1                      NM_153450
protein (LCMR1)
Suppression of tumorigenicity 7                1p13.2                       NM_017744
like (ST7L)

Hypothetical proteins  (15.7%)
CGI-141, hypothetical protein                  12p12.1                      AF_151899
CPEB4 (KIAA1673)                               5q21                         NM_030627
DKFZp667J0824                                  8q24.13                      AL_832830
DKFZp686C0927                                  11q13.1                      AL_832758
FISH (KIAA0418)                                10q25.1             2        NM_014631
FLJ10702, hypothetical protein                 3p26.1                       NM_018184
FLJ20275, hypothetical protein                 1p22.1                       NM_017737
FLJ21308, hypothetical protein                 5q11.1                       NM_024615
FLJ23680, hypothetical protein                 4q35.1                       AK_075260
FLJ36175, hypothetical protein                 2q24.2                       NM_152528
KIAA0377                                       15q15.3                      NM_014659
KIAA0774                                       13q12.3                      NM_015233
Ran binding protein 17 (RANBP17)               5q34                         NM_022897
RNF111 (DKFZp686H1966)                         15q21                        NM_017610
Similar to cyclic nucleotide gated             11q13.1             3        BX_538238
channel (cGMP, DKFZp686B0790)
Target of Nesh-SH3 (TARSH)                     3q12                         NM_015429

Lupien, Mol Vis 2007; 13:1828-1841 <http://www.molvis.org/molvis/v13/a204/>
©2007 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535