Figure 2. Visual cycle genes expressed in retinal pigment epithelium

The Protein Lounge database was used to identify cycle members. Some mRNAs for visual cycle proteins increased throughout development, others only during the late phase when photoreceptor outer segments are forming. The apparent variation of interphotoreceptor retinoid binding protein (IRBP) was statistically insignificant. Low signals with large statistical errors typified the few genes that are not expressed by retinal pigment epithelium, but were detected on the microarray. Mean values of 3-4 biological replicates are indicated according to the scale, in arbitrary units, depicted at the bottom. Complete gene titles and mean values with the associated p-statistic are listed in the corresponding Appendix 2.