Table 2 of
Wang, Mol Vis 2006;
12:852-857.
Table 2.
Genotype frequencies and probabilities of decorin, lumican, and DSPG3 sequence alterations in patients with myopia < -10 D and control subjects. In the table, 1/1 indicates a genotype with homozygous normal allele; 1/2 indicates a genotype with heterozygous sequence alterations; 2/2 indicates genotype with homozygous sequence alterations; and HWD indicates a χ2 statistic for Hardy-Weinberg disequilibrium. The asterisk indicates a p<0.05 for the Hardy-Weinberg equilibrium. The genotype p value is based on a χ2 test.
Genotype Frequency (%) ------------------------------------------------------ Patients (n=120) Control (n=137) Sequence -------------------------- ------------------------- Genotype Gene alternation 1/1 1/2 2/2 HWD 1/1 1/2 2/2 HWD p value ------- ---------------- --- --- --- -------- --- --- --- ------- -------- Decorin rs1803344 (C->G) 120 0 0 0 137 0 0 0 1.0000 rs3138268 (C->T) 120 0 0 0 137 0 0 0 1.0000 rs2070985 (C->G) 89 26 5 2.7118 107 25 5 4.4938* 0.7594 rs2070984 (A->G) 120 0 0 0 137 0 0 0 1.0000 Lumican rs1802763 (T->C) 120 0 0 0 137 0 0 0 1.0000 rs1802743 (G->T) 120 0 0 0 137 0 0 0 1.0000 rs2300588 (G->T) 11 56 53 0.4858 21 69 47 0.2766 0.1550 rs7135740 (A->T) 64 48 8 0.0620 54 68 15 0.8821 0.0698 rs3741835 (C->T) 65 47 8 0.0161 56 66 15 0.4654 0.0867 rs3741834 (C->T) 64 49 7 0.3579 56 65 16 0.1910 0.0743 rs3759223 (C->T) 61 32 27 21.1796* 55 68 14 1.1185 0.000283 rs3759222 (A->C) 18 55 47 0.0841 17 67 53 0.3515 0.8000 DSPG3 rs1135866 (A->G) 120 0 0 0 137 0 0 0 1.0000 rs1920748 (A->G) 4 13 103 12.4105* 1 14 122 0.6855 0.3124 rs1920751 (A->C) 8 32 80 3.3333 10 37 90 4.4571* 0.9761 rs1920752 (A->C) 7 33 80 1.9321 10 37 90 4.4571* 0.8946 |