Table 1 of
Chen, Mol Vis 2003;
9:735-746.
Table 1. Computer analysis of the initial 28 amino acids in MP19
Computer analysis of the MP19 amino acid sequence using several different prediction servers show that the first 26-28 amino acids serve as a signal anchor and peptide. As each amino acid is removed from the COOH-terminal end of the polypeptide, the fragments between 21 and 25 amino acids predict a signal anchor. As the truncations go below 21 amino acids, the peptide completely loses predictive function.
MYSFMGGGLFCAWVGTILLVVATATDHW 28 Prediction of a signal anchor and peptide MYSFMGGGLFCAWVGTILLVVATATDH 27 Prediction of a signal anchor and peptide MYSFMGGGLFCAWVGTILLVVATATD 26 Prediction of a signal anchor and peptide MYSFMGGGLFCAWVGTILLVVATAT 25 Prediction of a signal anchor MYSFMGGGLFCAWVGTILLVVATA 24 Prediction of a signal anchor MYSFMGGGLFCAWVGTILLVVAT 23 Prediction of a signal anchor MYSFMGGGLFCAWVGTILLVVA 22 Prediction of a signal anchor MYSFMGGGLFCAWVGTILLVV 21 Prediction of a signal anchor MYSFMGGGLFCAWVGTILLV 20 Nothing MYSFMGGGLFCAWVGTILL 19 Nothing |