Figure 1. Photoreceptor morphology and outer segment grading

Intact retinas were removed from stage 33/34 Xenopus laevis tadpoles and placed into culture in Niu-Twitty for 3 days. A: RPE-supported retina; B: RPE-deprived retina; C: Mannose-exposed RPE-deprived retina (5x10^-3 M); D: lactose-exposed RPE-deprived retina (5x10^-3 M); E: Summary graph of outer segment organization in A-D. The outer segment (OS), inner segment (IS), outer nuclear layer (ONL) are also labeled in the micrograph.