Figure 5 of
Cerra, Mol Vis 2003;
Figure 5. Effects of PDGF and FGF on TGFβ-induced lens opacification
Lenses from immature rats were cultured for 4 days with 0.5 ng/ml TGFβ alone (A) or with TGFβ plus PDGF (B) or TGFβ plus FGF (C) then photographed. TGFβ was used at a concentration of 0.5 ng/ml and PDGF and FGF were each used at a concentration of 10 ng/ml. Micrographs of representative lenses from each treatment group are shown. TGFβ induced numerous small discrete opacities in the lens anterior (A). Supplementing with FGF (C) but not PDGF (B) resulted in exacerbation of TGFβ-induced opacification.