Table 2 of
Dekomien, Mol Vis 2003;
9:601-605.Table 2 of
Dekomien, Mol Vis 2003;
9:601-605.
Table 2. Exon-/intron organization of the human and canine RPE65 genes
Comparison of the exon and intron lengths and homologous sequences of the splice sites of man and dog. Canine introns 2, 3, and 10 could not be amplified. Exon sequences are depicted in upper case, intron sequences in lower case (canine EMBL accession numbers see above; human DNA sequences from chromosome 1: EMBL accessions number AL139413).
Exon Intron
------------- -----------
Length Exon-/Intron Length
# (bp) boundaries # (bp)
----- -- -------- -------------------- -- ------
Dog 1 65 TGTCCATCCAgtgagtatgc 1 925
Human 69 TATCCAGTAAgtatctctgg 1184
Dog accttctcagAGTGGAGCAT
Human accatttcagGGTTGAGCAT
Dog 2 83 CACGTGACAG.......... 2 ?
Human 83 CATGTAACAGgttggtctcg 1763
Dog ..........GCAGGATCCC
Human ttcatcacagGCAGGATCCC
Dog 3 151 ATCACAGAAG.......... 3 ?
Human 151 ACCACAGAAGgtaaagcagc 1826
Dog ..........GTTCATCCGC
Human tgtccttcagGTTCATCCCG
Dog 4 108 TATTTTCCAGgttattgaaa 4 104
Human 108 TATTTTCCAGgttactgaac 103
Dog gcttctgtagGTTTTTTTCT
Human gtttctacagGTTTTTTTCT
Dog 5 142 AATTAAGCAGgtaggacgaa 5 ~2800
Human 142 AATTAAGCAGgtgggacaca 3530
Dog cctcccgcagGTTGATCTCT
Human acttccgtagGTTGATCTTT
Dog 6 148 CTCCAAGCAGgtcagtttac 6 ~2000
Human 148 CTGCAAGCAGgtgagtttac 1210
Dog tttatttcagACAAGGAAGA
Human tttatttcagACAAGGAAGA
Dog 7 82 ACGTCCATAGgtaacttgaa 7 227
Human 82 ACGTTCATAGgtaacttgaa 237
Dog ctctaaacagTTTTGGTTTG
Human ttctgaacagTTTTGGTCTG
Dog 8 133 AACCATGGGGgtaagtcggg 8 123
Human 133 ATGGGGGTAAgtcttagata 105
Dog atttttcaagGTTTGGCTTC
Human atttttcaagGTTTGGCTTC
Dog 9 140 GCTGGAAAGGgtaagagagg 9 ~1700
Human 140 GCTGGAAAGGgtaagaaagg 625
Dog atttttgcagATTTGAATTC
Human atttttgcagATTTGAGTTT
Dog 10 130 TATCGACAAG......... 10 ?
Human 130 TATTGACAAGgtaacctgct 6601
Dog ..........GCCGACACAG
Human tctctcctagGCTGACACAG
Dog 11 115 CCTCGTCAAGgtgaggtgat 11 330
Human 115 CCTCGTCAAGgtgagatgat 94
Dog tattttgtagCCTTTGAGTT
Human tatttcgtagCATTTGAGTT
Dog 12 95 TCCGGACAGGgtaccgctcc 12 320
Human 95 TCCAGATAGGgtaattaatc 105
Dog tcacaagcagCTCTGCAAGC
Human tcacaaacagCTCTGTAAGC
Dog 13 112 GAAGATGATGgtaatgaaag 13 ~1500
Human 112 GAAGATGATGgtaatgaaag 1137
Dog 14 152/734 tgattaacagGTGTAGTTCT
Human 152/1023 tgataaacagGTGTAGTTCT
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