Table 4 of Hawse, Mol Vis 2003; 9:515-537.


Table 4. Individual functionally clustered genes

The table lists all genes comprising each of the sub-categories that were significantly altered between cataract and clear lenses.

Increased In Cataract

    Probe                                          Accession     Fold
    number                Gene name                 number      change
    ------   -----------------------------------   ---------   --------
Biological Process

  Chromosome organization

    200679   high-mobility group (nonhistone       NM_002128     4.5948
             chromosomal) protein 1
    205062   retinoblastoma-binding protein 1      NM_002892     4.9246
             (RBBP1)
    208859   alpha thalassemiamental retardation   NM_000489     5.6569
             syndrome X-linked
    209258   chondroitin sulfate proteoglycan 6    NM_005445     8.5742
             (bamacan)
    209715   heterochromatin protein homologue     NM_012117     4.0000
             (HP1)

  Nuclear organization

    200679   high-mobility group (nonhistone       NM_000489     4.5948
             chromosomal) protein 1
    205062   retinoblastoma-binding protein 1      NM_002892     4.9246
             (RBBP1)
    208859   alpha thalassemiamental retardation   NM_000489     5.6569
             syndrome X-linked
    209258   chondroitin sulfate proteoglycan 6    NM_005445     8.5742
             (bamacan)
    209715   heterochromatin protein homologue     NM_012117     4.0000
             (HP1)

  Transcription/DNA-dependent

    200679   high-mobility group (nonhistone       NM_002128     4.5948
             chromosomal) protein 1
    201138   Sjogren syndrome antigen B            NM_003142     6.4980
    202173   zinc finger protein 161               NM_007146     6.9644
    202600   nuclear receptor interacting          NM_003489     7.4643
             protein 1
    202612   cofactor required for Sp1             NM_004229    16.0000
             transcriptional activation, subunit
             2
    204771   transcription termination factor,     NM_007344     4.0000
             RNA polymerase I
    205062   retinoblastoma-binding protein 1      NM_002892     4.9246
             (RBBP1)
    205070   inhibitor of growth family, member    NM_019071      4.2871
             3
    205443   small nuclear RNA activating          NM_003082     6.9644
             complex
    205596   E3 ubiquitin ligase Smurf2            NM_022739     4.5948
    206848   homeo box A7                          NM_006896     4.2871
    208003   nuclear factor of activated T-cells   NM_006599     4.2871
             5
    208859   alpha thalassemiamental retardation   NM_000489     5.6569
             syndrome X-linked
    209088   ubinuclein 1                          T70262        5.6569
    210504   erythroid-specific transcription      NM_006563     5.2780
             factor
    212079   myeloidlymphoid or mixed-lineage      NM_005933    19.6983
             leukemia
    212492   KIAA0876 protein                      AW237172      6.9644

  Transcription

    200679   high-mobility group (nonhistone       NM_002128     4.5948
             chromosomal) protein 1
    201138   Sjogren syndrome antigen B            NM_003142     6.4980
    201606   nuclear phosphoprotein                NM_007062     5.2780
    202173   zinc finger protein 161               NM_007146     6.9644
    202600   nuclear receptor interacting          NM_003489     7.4643
             protein 1
    202612   cofactor required for Sp1             NM_004229     16.0000
             transcriptional activation, subunit
             2
    204771   transcription termination factor,     NM_007344      4.0000
             RNA polymerase I
    205062   retinoblastoma-binding protein 1      NM_002892     4.9246
             (RBBP1)
    205070   inhibitor of growth family, member    NM_019071      4.2871
             3
    205443   small nuclear RNA activating          NM_003082     6.9644
             complex
    205596   E3 ubiquitin ligase Smurf2            NM_022739     4.5948
    206848   homeo box A7                          NM_006896     4.2871
    208003   nuclear factor of activated T-cells   NM_006599     4.2871
             5
    208859   alpha thalassemiamental retardation   NM_000489     5.6569
             syndrome X-linked
    209088   ubinuclein 1                          T70262        5.6569
    210504   erythroid-specific transcription      NM_006563     5.2780
             factor
    212079   myeloidlymphoid or mixed-lineage      NM_005933    19.6983
             leukemia
    212492   KIAA0876 protein                      AW237172      6.9644

  Nucleic acid metabolism

    200679   high-mobility group (nonhistone       NM_002128     4.5948
             chromosomal) protein 1
    201138   Sjogren syndrome antigen B            NM_003142     6.4980
    201606   nuclear phosphoprotein                NM_007062     5.2780
    202173   zinc finger protein 161               NM_007146     6.9644
    202600   nuclear receptor interacting          NM_003489     7.4643
             protein 1
    202612   cofactor required for Sp1             NM_004229    16.0000
             transcriptional activation, subunit
             2
    202905   Nijmegen breakage syndrome 1          NM_002485     6.9644
             (nibrin)
    204771   transcription termination factor,     NM_007344     4.0000
             RNA polymerase I
    205062   retinoblastoma-binding protein 1      NM_002892     4.9246
             (RBBP1)
    205070   inhibitor of growth family, member    NM_019071     4.2871
             3
    205443   small nuclear RNA activating          NM_003082     6.9644
             complex
    205596   E3 ubiquitin ligase Smurf2            NM_022739     4.5948
    206848   homeo box A7                          NM_006896     4.2871
    208003   nuclear factor of activated T-cells   NM_006599     4.2871
             5
    208835   cisplatin resistance-associated       AW089673      4.2871
             overexpressed protein
    208859   alpha thalassemiamental retardation   NM_000489     5.6569
             syndrome X-linked
    209024   NS1-associated protein 1              AF037448      4.9246
    209088   ubinuclein 1                          T70262        5.6569
    209579   methyl-CpG binding domain protein 4   NM_003925     4.2871
    209715   heterochromatin protein homologue     NM_012117     4.0000
             (HP1)
    210504   erythroid-specific transcription      NM_006563     5.2780
             factor
    212079   myeloidlymphoid or mixed-lineage      NM_005933    19.6983
             leukemia
    212492   KIAA0876 protein                      AW237172      6.9644

Molecular Function

  Nucleic acid binding

    200679   high-mobility group (nonhistone       NM_002128     4.5948
             chromosomal) protein 1
    201138   Sjogren syndrome antigen B            NM_003142     6.4980
    201635   fragile X mental retardation,         NM_005087     4.5948
             autosomal homolog 1
    202173   zinc finger protein 161               NM_007146     6.9644
    202612   cofactor required for Sp1             NM_004229    16.0000
             transcriptional activation, subunit
             2
    202905   Nijmegen breakage syndrome 1          NM_002485     6.9644
             (nibrin)
    203567   ring finger protein 15                NM_006355    19.6983
    204771   transcription termination factor,     NM_007344     4.0000
             RNA polymerase I
    205062   retinoblastoma-binding protein 1      NM_002892     4.9246
             (RBBP1)
    205070   inhibitor of growth family, member    NM_019071     4.2871
             3
    206848   homeo box A7                          NM_006896     4.2871
    208003   nuclear factor of activated T-cells   NM_006599     4.2871
             5
    208325   lymphoid blast crisis oncogene        NM_006738     4.2871
    208624   eukaryotic translation initiation     AF104913      6.4980
             factor 4 gamma
    208859   alpha thalassemiamental retardation   NM_000489     5.6569
             syndrome X-linked
    209024   NS1-associated protein 1              AF037448      4.9246
    209088   ubinuclein 1                          T70262        5.6569
    209579   methyl-CpG binding domain protein 4   NM_003925     4.2871
    209715   heterochromatin protein homologue     NM_012117     4.0000
             (HP1)
    210504   erythroid-specific transcription      NM_006563     5.2780
             factor
    212079   myeloidlymphoid or mixed-lineage      NM_005933    19.6983
             leukemia
    212492   KIAA0876 protein                      AW237172      6.9644

  Ligand binding or carrier

    200679   high-mobility group (nonhistone       NM_002128     4.5948
             chromosomal) protein 1
    201138   Sjogren syndrome antigen B            NM_003142     6.4980
    201242   ATPase, Na+K+ transporting, beta      BC000006      8.0000
             1
    201635   fragile X mental retardation,         NM_005087     4.5948
             autosomal homolog 1
    201711   RAN binding protein 2                 NM_006267     4.5948
    201752   adducin 3 (gamma)                     NM_019903     6.0629
    201777   KIAA0494 gene product                 NM_014774    17.1484
    202082   SEC14                                 NM_003003     4.9246
    202118   copine III                            NM_003909     6.9644
    202173   zinc finger protein 161               NM_007146     6.9644
    202600   nuclear receptor interacting          NM_003489     7.4643
             protein 1
    202612   cofactor required for Sp1             NM_004229    16.0000
             transcriptional activation, subunit
             2
    202831   glutathione peroxidase 2              NM_002083     8.0000
    202905   Nijmegen breakage syndrome 1          NM_002485     6.9644
             (nibrin)
    203567   ring finger protein 15                NM_006355    19.6983
    204771   transcription termination factor,     NM_007344     4.0000
             RNA polymerase I
    205062   retinoblastoma-binding protein 1      NM_002892     4.9246
             (RBBP1)
    205070   inhibitor of growth family, member    NM_019071     4.2871
             3
    205809   Wiskott-Aldrich syndrome-like         NM_003941    14.9285
    206848   homeo box A7                          NM_006896     4.2871
    207152   neurotrophic tyrosine kinase,         NM_006180     4.0000
             receptor, type 2
    208003   nuclear factor of activated T-cells   NM_006599     4.2871
             5
    208325   lymphoid blast crisis oncogene        NM_006738     4.2871
    208624   eukaryotic translation initiation     AF104913      6.4980
             factor 4 gamma
    208859   alpha thalassemiamental retardation   NM_000489     5.6569
             syndrome X-linked
    209024   NS1-associated protein 1              AF037448      4.9246
    209088   ubinuclein 1                          T70262        5.6569
    209258   chondroitin sulfate proteoglycan 6    NM_005445     8.5742
             (bamacan)
    209466   pleiotrophin                          M57399        7.4643
    209579   methyl-CpG binding domain protein 4   NM_003925     4.2871
    209715   heterochromatin protein homologue     NM_012117     4.0000
             (HP1)
    210504   erythroid-specific transcription      NM_006563     5.2780
             factor
    212079   myeloidlymphoid or mixed-lineage      NM_005933    19.6983
             leukemia
    212492   KIAA0876 protein                      AW237172      6.9644
    212926   KIAA0594 protein                      AW183677      9.1896
    214464   Ser-Thr protein kinase                NM_003607     6.4980
    214933   calcium channel, voltage-             AA769818      4.9246
             dependent, PQ type, alpha 1A

  DNA binding

    200679   high-mobility group (nonhistone       NM_002128     4.5948
             chromosomal) protein 1
    202173   zinc finger protein 161               NM_007146     6.9644
    202612   cofactor required for Sp1             NM_004229    16.0000
             transcriptional activation, subunit
             2
    202905   Nijmegen breakage syndrome 1          NM_002485     6.9644
             (nibrin)
    204771   transcription termination factor,     NM_007344     4.0000
             RNA polymerase I
    205062   retinoblastoma-binding protein 1      NM_002892     4.9246
             (RBBP1)
    205070   inhibitor of growth family, member    NM_019071     4.2871
             3
    206848   homeo box A7                          NM_006896     4.2871
    208003   nuclear factor of activated T-cells   NM_006599     4.2871
             5
    208859   alpha thalassemiamental retardation   NM_000489     5.6569
             syndrome X-linked
    209088   ubinuclein 1                          T70262        5.6569
    209579   methyl-CpG binding domain protein 4   NM_003925     4.2871
    209715   heterochromatin protein homologue     NM_012117     4.0000
             (HP1)
    210504   erythroid-specific transcription      NM_006563     5.2780
             factor
    212079   myeloidlymphoid or mixed-lineage      NM_005933    19.6983
             leukemia
    212492   KIAA0876 protein                      AW237172      6.9644

 

Decreased In Cataract

    Probe                                          Accession     Fold
    number                Gene name                 number      change
    ------   -----------------------------------   ---------   --------
Biological Process

  RNA splicing

    200826   small nuclear ribonucleoprotein D2    NM_004597     4.5948
             polypeptide
    201698   splicing factor,                      NM_003769     6.0629
             arginineserine-rich 9
    202567   small nuclear ribonucleoprotein D3    NM_004175     4.5948
             polypeptide
    204559   U6 snRNA-associated Sm-like protein   NM_016199    10.5561
             LSm7
    208880   putative mitochondrial outer          AB019219      4.5948
             membrane protein import receptor
    209449   SMX5-like protein                     AF196468      5.6569

  Protein biosynthesis

    200005   eukaryotic translation initiation     NM_003753     4.9246
             factor 3, subunit 7
    200689   eukaryotic translation elongation     NM_001404    10.5561
             factor 1 gamma
    201064   poly(A)-binding protein,              NM_003819     6.9644
             cytoplasmic 4
    201263   threonyl-tRNA synthetase              NM_003191     6.0629
    201530    eukaryotic translation initiation    NM_001416     4.2871
             factor 4A, isoform 1
    201632   eukaryotic translation initiation     NM_001414     6.0629
             factor 2B, subunit 1
    201841   heat shock 27 kDa protein 1           NM_001540   128.0000
    202021   SUI1 isolog                           AF083441      4.5948
    202042   histidyl-tRNA synthetase              NM_002109    12.9960
    203113   eukaryotic translation elongation     NM_001960     6.4980
             factor 1 delta
    203725   growth arrest and                     NM_001924    24.2515
             DNA-damage-inducible, alpha
    204102   eukaryotic translation elongation     NM_001961    21.1121
             factor 2
    208856   ribosomal protein, large, P0          BC003655      4.5948
    208887   eukaryotic translation initiation     BC000733      8.0000
             factor 3, subunit 4
    210213   translation initiation factor 6       AF022229      4.0000

  Protein synthesis elongation

    200689   eukaryotic translation elongation     NM_001404    10.5561
             factor 1 gamma
    203113   eukaryotic translation elongation     NM_001960     6.4980
             factor 1 delta
    204102   eukaryotic translation elongation     NM_001961    21.1121
             factor 2
    208856   ribosomal protein, large, P0          BC003655      4.5948

  Protein synthesis initiation

    201530    eukaryotic translation initiation    NM_001416     4.2871
             factor 4A, isoform 1
    201632   eukaryotic translation initiation     NM_001414     6.0629
             factor 2B, subunit 1
    202021   SUI1 isolog                           AF083441      4.5948
    210213   translation initiation factor 6       AF022229      4.0000

  Macromolecule biosynthesis

    200005   eukaryotic translation initiation     NM_003753     4.9246
             factor 3, subunit 7
    200689   eukaryotic translation elongation     NM_001404    10.5561
             factor 1 gamma
    201064   poly(A)-binding protein,              NM_003819     6.9644
             cytoplasmic 4
    201263   threonyl-tRNA synthetase              NM_003191     6.0629
    201530    eukaryotic translation initiation    NM_001416     4.2871
             factor 4A, isoform 1
    201632   eukaryotic translation initiation     NM_001414     6.0629
             factor 2B, subunit 1
    201841   heat shock 27 kDa protein 1           NM_001540   128.0000
    202021   SUI1 isolog                           AF083441      4.5948
    202042   histidyl-tRNA synthetase              NM_002109    12.9960
    203113   eukaryotic translation elongation     NM_001960     6.4980
             factor 1 delta
    203725   growth arrest and                     NM_001924    24.2515
             DNA-damage-inducible, alpha
    204102   eukaryotic translation elongation     NM_001961    21.1121
             factor 2
    208856   ribosomal protein, large, P0          BC003655      4.5948
    208887   eukaryotic translation initiation     BC000733      8.0000
             factor 3, subunit 4
    210213   translation initiation factor 6       AF022229      4.0000

  Amine biosynthesis

    200790   ornithine decarboxylase 1             NM_002539     4.9246
    201772   antizyme inhibitor                    NM_015878     6.9644
    207621   phosphatidylethanolamine              NM_007169     6.0629
             N-methyltransferase

  Peroxidase reaction

    200736   glutathione peroxidae 1 (GPX1)        NM_000581     4.9246
    201106   glutathione peroxidase 4              NM_002085     4.2871
             (phospholipid hydroperoxidase)
    201348   glutathione peroxidase 3 (GPX3)       NM_002084    11.3137
    212013   KIAA0230 gene                         D86983       12.1257

  Microtubule-based process

    200712   microtubule-associated protein,       AI633566     10.5561
             RPEB family, member 1
    200750   GTP binding protein                   AF054183      4.9246
    203690   spindle pole body protein (GCP3)      NM_006322     9.1896
    204398   microtubule-associated protein like   NM_012155     4.9246
             echinoderm EMAP
    205191   retinitis pigmentosa 2                NM_006915    12.1257
    208786   microtubule-associated proteins       AF183417      5.6569
             1A1B light chain 3
    208977   tubulin, beta, 2                      BC004188      6.0629
    209191   Similar to tubulin, beta, 4           BC002654      7.4643

  Organelle organization

    200712   microtubule-associated protein,       AI633566     10.5561
             RPEB family, member 1
    200750   GTP binding protein                   AF054183      4.9246
    200866   saposin proteins A-D                  M32221       18.3800
    201707   peroxisomal farnesylated protein      NM_002857     4.0000
    201821   translocase of inner mitochondrial    BC004439      9.1896
             membrane 17
    203690   spindle pole body protein (GCP3)      NM_006322     9.1896
    204398   microtubule-associated protein like   NM_012155     4.9246
             echinoderm EMAP
    205191   retinitis pigmentosa 2                NM_006915    12.1257
    208786   microtubule-associated proteins       AF183417      5.6569
             1A1B light chain 3
    208977   tubulin, beta, 2                      BC004188      6.0629
    209191   Similar to tubulin, beta, 4           BC002654      7.4643

  Cytoskeleton organization

    200712   microtubule-associated protein,       AI633566     10.5561
             RPEB family, member 1
    200750   GTP binding protein                   AF054183      4.9246
    203690   spindle pole body protein (GCP3)      NM_006322     9.1896
    204398   microtubule-associated protein like   NM_012155     4.9246
             echinoderm EMAP
    205191   retinitis pigmentosa 2                NM_006915    12.1257
    208786   microtubule-associated proteins       AF183417      5.6569
             1A1B light chain 3
    208977   tubulin, beta, 2                      BC004188      6.0629
    209191   Similar to tubulin, beta, 4           BC002654      7.4643

  Temperature response

    200064   isolate Liv chaperone protein HSP90   AF275719      4.9246
             beta
    200664   DnaJ (Hsp40) homolog, subfamily B,    BG537255      6.4980
             member 1
    200797   myeloid cell leukemia sequence 1      AI275690      4.0000
             (BCL2-related)
    200800   heat shock 70 kDa protein 1A          NM_005345     4.0000
    201161   cold shock domain protein A           NM_003651     5.6569
    201841   heat shock 27 kDa protein 1           NM_001540   128.0000
    202581   heat shock 70 kDa protein 1B          NM_005346     5.6569
    205824   heat shock 27 kDa protein 2           NM_001541     5.2780

  Heat shock response

    200064   isolate Liv chaperone protein HSP90   AF275719      4.9246
             beta
    200664   DnaJ (Hsp40) homolog, subfamily B,    BG537255      6.4980
             member 1
    200797   myeloid cell leukemia sequence 1      AI275690      4.0000
             (BCL2-related)
    200800   heat shock 70 kDa protein 1A          NM_005345     4.0000
    201841   heat shock 27 kDa protein 1           NM_001540   128.0000
    202581   heat shock 70 kDa protein 1B          NM_005346     5.6569
    205824   heat shock 27 kDa protein 2           NM_001541     5.2780

  Vision

    201563   L-iditol-2 dehydrogenase              L29008       12.1257
    201842   EGF-containing fibulin-like           AI826799      4.9246
             extracellular matrix protein 1
    202766   fibrillin 1                           NM_000138     5.2780
    204398   microtubule-associated protein like   NM_012155     4.9246
             echinoderm EMAP
    205191   retinitis pigmentosa 2                NM_006915    12.1257
    206777   beta B2 crystallin                    NM_000496     6.4980
    206843   beta A4 crystallin                    NM_001886   168.8970
    207399   phakinin, beaded filament             NM_003571    12.9960
             structural protein 2
    207532   gamma D crystallin                    NM_006891    29.8571
    207685   beta B3 crystallin                    NM_004076    22.6274

  Response to external stimulus

    200064   isolate Liv chaperone protein HSP90   AF275719      4.9246
             beta
    200664   DnaJ (Hsp40) homolog, subfamily B,    BG537255      6.4980
             member 1
    200797   myeloid cell leukemia sequence 1      AI275690      4.0000
             (BCL2-related)
    200800   heat shock 70 kDa protein 1A          NM_005345     4.0000
    201064   poly(A)-binding protein,              NM_003819     6.9644
             cytoplasmic 4
    201161   cold shock domain protein A           NM_003651     5.6569
    201315   interferon induced transmembrane      NM_006435     4.5948
             protein 2
    201348   glutathione peroxidase 3 (GPX3)       NM_002084    11.3137
    201563   L-iditol-2 dehydrogenase              L29008       12.1257
    201841   heat shock 27 kDa protein 1           NM_001540   128.0000
    201842   EGF-containing fibulin-like           AI826799      4.9246
             extracellular matrix protein 1
    201891   beta-2-microglobulin                  NM_004048     4.2871
    202581   heat shock 70 kDa protein 1B          NM_005346     5.6569
    202727   interferon gamma receptor 1           NM_000416     4.0000
    202766   fibrillin 1                           NM_000138     5.2780
    203725   growth arrest and                     NM_001924    24.2515
             DNA-damage-inducible, alpha
    203921   carbohydrate (chondroitin 6keratan)   NM_004267     4.5948
             sulfotransferase 2
    204398   microtubule-associated protein like   NM_012155     4.9246
             echinoderm EMAP
    205081   cysteine-rich protein 1               NM_001311    14.9285
    205191   retinitis pigmentosa 2                NM_006915    12.1257
    205824   heat shock 27 kDa protein 2           NM_001541     5.2780
    206777   beta B2 crystallin                    NM_000496     6.4980
    206843   beta A4 crystallin                    NM_001886   168.8970
    207399   phakinin, beaded filament             NM_003571    12.9960
             structural protein 2
    207532   gamma D crystallin                    NM_006891    29.8571
    207685   beta B3 crystallin                    NM_004076    22.6274
    208650   CD24 antigen                          BG327863      4.9246
    208791   complement cytolysis inhibitor        M25915        4.2871
    208910   pre-mRNA splicing factor 2 p32        L04636        7.4643
             subunit
    209189   v-fos FBJ murine osteosarcoma viral   BC004490     12.1257
             oncogene homolog
    212013   KIAA0230 gene                         D86983       12.1257
    216598   monocyte chemotactic protein          S69738        6.4980

Molecular Function

  U6 snRNA binding

    204559   U6 snRNA-associated Sm-like protein   NM_016199    10.5561
             LSm7
    209449   SMX5-like protein                     AF196468      5.6569

  Pre-mRNA splicing factor

    200826   small nuclear ribonucleoprotein D2    NM_004597     4.5948
             polypeptide
    201698   splicing factor,                      NM_003769     6.0629
             arginineserine-rich 9
    202567   small nuclear ribonucleoprotein D3    NM_004175     4.5948
             polypeptide
    204559   U6 snRNA-associated Sm-like protein   NM_016199    10.5561
             LSm7
    208880   putative mitochondrial outer          AB019219      4.5948
             membrane protein import receptor
    209449   U6 snRNA-associated Sm-like protein   AF196468      5.6569

  mRNA binding

    200826   small nuclear ribonucleoprotein D2    NM_004597     4.5948
             polypeptide
    201064   poly(A)-binding protein,              NM_003819     6.9644
             cytoplasmic 4
    201530   eukaryotic translation initiation     NM_001416     4.2871
             factor 4A, isoform 1
    201698   splicing factor,                      NM_003769     6.0629
             arginineserine-rich 9
    202567   small nuclear ribonucleoprotein D3    NM_004175     4.5948
             polypeptide
    204559   U6 snRNA-associated Sm-like protein   NM_016199    10.5561
             LSm7
    208880   putative mitochondrial outer          AB019219      4.5948
             membrane protein import receptor
    209449   U6 snRNA-associated Sm-like protein   AF196468      5.6569

  Proteasome endopeptidase

    200786   proteasome                            NM_002799     6.0629
             (prosome,macropain)subunit,beta
             type, 1
    200876   proteasome                            NM_002793     8.5742
             (prosome,macropain)subunit,beta
             type, 1
    201532   proteasome                            NM_002788     5.6569
             (prosome,macropain)subunit,alpa
             type, 3
    202243   proteasome                            NM_002796     5.2780
             (prosome,macropain)subunit,beta
             type, 4

  Translation factor

    200005   eukaryotic translation initiation     NM_003753     4.9246
             factor 3, subunit 7
    200689   eukaryotic translation elongation     NM_001404    10.5561
             factor 1 gamma
    201530   eukaryotic translation initiation     NM_001416     4.2871
             factor 4A, isoform 1
    201632   eukaryotic translation initiation     NM_001414     6.0629
             factor 2B, subunit 1
    202021   SUI1 isolog                           AF083441      4.5948
    203113   eukaryotic translation elongation     NM_001960     6.4980
             factor 1 delta
    204102   eukaryotic translation elongation     NM_001961    21.1121
             factor 2
    208887   eukaryotic translation initiation     BC000733      8.0000
             factor 3, subunit 4
    210213   translation initiation factor 6       AF022229      4.0000

  Selenium binding

    200736   glutathione peroxidase 1              NM_000581     4.9246
    201106   glutathione peroxidase 4              NM_002085     4.2871
             (phospholipid hydroperoxidase)
    201194   selenoprotein W, 1 (SEPW1)            NM_003009     6.4980
    201348   glutathione peroxidase 3 (GPX3)       NM_002084    11.3137

  Alcohol dehydrogenase

    201563   L-iditol-2 dehydrogenase              L29008       12.1257
    210609   quinone oxidoreductase homolog        BC000474     11.3137
    213540   beta3-Galactosyltransferase           AL031228      6.0629

  Heat shock protein

    200064   isolate Liv chaperone protein HSP90   AF275719      4.9246
             beta
    200664   DnaJ (Hsp40) homolog, subfamily B,    BG537255      6.4980
             member 1
    200800   heat shock 70 kDa protein 1A          NM_005345     4.0000
    201841   heat shock 27 kDa protein 1           NM_001540   128.0000
    202581   heat shock 70 kDa protein 1B          NM_005346     5.6569
    205824   heat shock 27 kDa protein 2           NM_001541     5.2780

  Oxidoreductase

    200736   glutathione peoxidase 1 (GPX1)        NM_000581     4.9246
    201106   glutathione peroxidase 4              NM_002085     4.2871
             (phospholipid hydroperoxidase)
    201194   selenoprotein W, 1 (SEPW1)            NM_003009     6.4980
    201348   glutathione peroxidase 3 (GPX3)       NM_002084    11.3137
    201563   L-iditol-2 dehydrogenase              L29008       12.1257
    201892   inosine monophosphate dehydrogenase   NM_000884     5.2780
             2 (IMPDH2)
    202201   biliverdin reductase B(flavin         NM_000713     5.6569
             reductase (NADPH))
    202539   3-hydroxy-3-methylglutaryl-Coenzyme   M11058
    202785   NADH dehydroxygenase (ubiquinone)     NM_005001    12.9960
             1 alpha subcomplex, 7                               5.6569
             A reductase
    202839   NADH dehydroxygenase (ubiquinone)     NM_004146     4.5948
             1 beta subcomplex, 7
    203570   lysyl oxidase-like 1 (LOXL1)          NM_005576    21.1121
    206024   4-hydroxyphenylpyruvate dioxygenase   NM_002150     5.2780
    208631   78 kDa gastrin-binding protein        U04627       10.5561
    209213   carbonyl reductase 1                  BC002511      5.2780
    210609   quinone oxidoreductase homolog        BC000474     11.3137
    212013   melenoma associated gene              D86983       12.1257
    212224   aldehyde dehydrogenase 1 (ALDH1)      AF003341      4.0000
    213540   contains BING5 gene, the gene for     AL031228      6.0629
             beta3-galactosyltransferase

  Glutathione peroxidase

    200736   glutathione peroxidae 1 (GPX1)        NM_000581     4.9246
    201106   glutathione peroxidase 4              NM_002085     4.2871
             (phospholipid hydroperoxidase)
    201348   glutathione peroxidase 3 (GPX3)       NM_002084    11.3137

  Chaperone

    200064   isolate Liv chaperone protein HSP90   AF275719      4.9246
             beta
    200664   DnaJ (Hsp40) homolog, subfamily B,    BG537255      6.4980
             member 1
    200800   heat shock 70 kDa protein 1A          NM_005345     4.0000
    200812   chaperonin containing TCP1,           NM_006429     4.9246
             subunit 7
    200968   peptidylprolyl isomerase B            NM_000942    17.1484
             (cyclophilin B)
    201459   RuvB                                  NM_006666    16.0000
    201841   heat shock 27 kDa protein 1           NM_001540   128.0000
    202416   tetratricopeptide repeat domain 2     NM_003315     6.9644
    202581   heat shock 70 kDa protein 1B          NM_005346     5.6569
    202843   microvascular endothelial             NM_012328    27.8576
             differentiation gene 1
    205191   retinitis pigmentosa 2                NM_006915    12.1257
    205824   heat shock 27 kDa protein 2           NM_001541     5.2780
    207132   prefoldin 5                           NM_002624     6.9644

  Structural constituent of lens

    206746   filensin, beaded filament             NM_001195    17.1484
             structural protein 1
    206777   beta B2 crystallin                    NM_000496     6.4980
    206778   beta B2 crystallin                    NM_000496    12.1257
    206843   beta A4 crystallin                    NM_001886   168.8970
    207399   phakinin, beaded filament             NM_003571    12.9960
             structural protein 2
    207532   gamma D crystallin                    NM_006891    29.8571
    207685   beta B3 crystallin                    NM_004076    22.6274
    207715   crystallin, gamma B                   NM_005210     6.4980

  Structural molecule

    200600   moesin                                NM_002444     9.8492
    200696   gelsolin                              NM_000177     4.2871
    201650   keratin 19                            NM_002276     4.9246
    202007   nidogen (enactin)                     BF940043      8.5742
    202766   fibrillin 1                           NM_000138     5.2780
    203690   spindle pole body protein             NM_006322     9.1896
    203725   growth arrest and                     NM_001924    24.2515
             DNA-damage-inducible, alpha
    205373   catenin (cadherin-associated          NM_004389     6.9644
             protein), alpha 2
    206746   filensin, beaded filament             NM_001195    17.1484
             structural protein 1
    206777   beta B2 crystallin                    NM_000496     6.4980
    206778   beta B2 crystallin                    NM_000496    12.1257
    206843   beta A4 crystallin                    NM_001886   168.8970
    207399   phakinin, beaded filament             NM_003571    12.9960
             structural protein 2
    207532   gamma D crystallin                    NM_006891    29.8571
    207685   beta B3 crystallin                    NM_004076    22.6274
    207715   gamma B crystallin                    NM_005210     6.4980
    208611   alpha II spectrin                     U83867        8.0000
    208856   ribosomal protein, large, P0          BC003655      4.5948
    208977   tubulin, beta, 2                      BC004188      6.0629
    209191   Similar to tubulin, beta, 4           BC002654      7.4643
    210987   tropomyosin                           M19267        4.0000
    214953   amyloid beta (A4)                     X06989        4.0000

Hawse, Mol Vis 2003; 9:515-537 <http://www.molvis.org/molvis/v9/a65/>
©2003 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535