Table 4 of Powell, Mol Vis 2003; 9:460-464.

Table 4. Genotype frequencies of the compound OPA1 IVS8 polymorphism

The CC/CC genotype is associated with NTG but it is the presence of the +32 CC that it is truly significant.

Genotype (n)   Normals (%)    NTG (%)
   +4/+32         n=168        n=61      p value
------------   -----------   ---------   -------
 CC/TT (29)     21 (12.5)     8 (13.1)    0.90
 CC/TC (85)     69 (41.1)    16 (26.2)    0.04
 CC/CC (38)     21 (12.5)    17 (27.9)    0.006
 CT/TT (23)     18 (10.7)     5  (8.2)    0.58
 CT/TC (46)     35 (20.8)    11 (18.0)    0.64
 TT/TT  (8)      4  (2.4)     4  (6.6)    0.15
Powell, Mol Vis 2003; 9:460-464 <http://www.molvis.org/molvis/v9/a58/>
©2003 Molecular Vision <http://www.molvis.org/molvis/>
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