Table 3 of
Powell, Mol Vis 2003;
9:460-464.
Table 3. Genotype frequencies at the +4 and +32 locations of OPA1 IVS8
The +32 CC genotype is associated more than twice as often with NTG compared to controls (p=0.006).
Normals (%) NTG (%) Location Genotype n=168 n=61 -------- -------- ----------- --------- +4: CC 111 (66.1) 41 (67.2) CT 53 (31.5) 16 (26.2) TT 4 (2.4) 4 (6.6) chi-square=2.663; dof=2; p=0.26 +32: TT 43 (25.6) 17 (27.9) TC 104 (61.9) 27 (44.3) CC 21 (12.5) 17 (27.9) chi-square=8.893; dof=2; p=0.012 |