Table 2 of
Wride, Mol Vis 2003;
9:360-396.Table 2 of
Wride, Mol Vis 2003;
9:360-396.
Table 2. Onto-ExpressTM analysis of the 1,668 genes expressed at above background plus 2 SD levels in at least one of the lens samples
Results of Onto-ExpressTM analysis of the 1,668 genes expressed at above background plus 2 SD levels in at least one of the lens samples to determine the biological processes in which they are involved according to Gene OntologyTM. The genes are listed in their categories in descending order of number of genes per category. P values are calculated by Onto-ExpressTM by comparing the proportion of genes in a given category identified using the microarray with the total complement of genes in that category on the array. Thereby, groups of genes with smaller p values are represented in the microarray data in greater numbers than would be expected (transcription factors p=0.047; G-Protein Coupled Receptor Signaling Pathway p=0.014). Categories with p<0.05 are labeled with an asterisk ("*"). Genes may appear in more than one category if they have more than one GeneOntologyTM term associated with them.
Biological Cluster Locus Accession
process ID ID number(s) Gene name p value
----------------- ------- ------ --------- ------------------------------------------------------- -------
transcription regulation*
4316 11863 AI451564 aryl hydrocarbon receptor nuclear translocator 0.047
9524 17684 AI430768 Cbp/p300-interacting transactivator, with Glu/Asp-rich
carboxy-terminal domain, 2
7549 13198 AI323295 DNA-damage inducible transcript 3
4303 14056 AI323840 enhancer of zeste homolog 2 (Drosophila)
28619 23894 AI327310 general transcription factor II H, polypeptide 2 (44
kDa subunit)
29630 14887 AI429623 general transcription factor III C 1
22216 14605 AI326808 glucocorticoid-induced leucine zipper
215 15414 AI385768 homeo box B6
26544 15438 AI385671 homeo box D9
7320 17127 AI324173 MAD homolog 3 (Drosophila)
100399 17128 AI427147 MAD homolog 4 (Drosophila)
10563 17765 AI448197 metal response element binding transcription factor 2
101277 29861 AI430751 neuronal d4 domain family member
6549 17937 AI385556 Ngfi-A binding protein 2
4918 14815 AI447752 nuclear receptor subfamily 3, group C, member 1
3507 18227 AI429298 nuclear receptor subfamily 4, group A, member 2
27220 18046 AI448923 nuclear transcription factor-Y gamma
10723 18628 AI428816 period homolog 3 (Drosophila)
304 19645 AI323835 retinoblastoma 1
28027 19651 AI323872 retinoblastoma-like 2
4081 12394 AI451932 runt related transcription factor 1
8249 20846 AI449540 signal transducer and activator of transcription 1
21642 20728 AI451311 Spi-C transcription factor (Spi-1/PU.1 related)
4605 21385 AI448932 T-box 2
103636 21388 AI464523 T-box 5
3406 21423 AI324257 transcription factor E2a
15755 20466 AI426974 transcriptional regulator, SIN3A (yeast)
2137 20467 AI327204 transcriptional regulator, SIN3B (yeast)
15781 22282 AI893650 upstream transcription factor 2
28230 17134 AI428545 v-maf musculoaponeurotic fibrosarcoma oncogene family,
protein G (avian)
3868 22632 AI447233 YY1 transcription factor
protein amino acid phosphorylation
29133 12236 AI465548 budding uninhibited by benzimidazoles 1 homolog, beta 0.286
(S. cerevisiae)
30199 27373 AI449651 casein kinase 1, epsilon
18268 12748 AI661472 CDC-like kinase 2
118 12566 AI323666 cyclin-dependent kinase 2
8534 13649 AI427644 epidermal growth factor receptor
25120 26559 AI426929 hormonally upregulated Neu-associated kinase
16009 16428 AI528630 IL2-inducible T-cell kinase
142 16818 AI573454 lymphocyte protein tyrosine kinase
27970 26415 AI894223 mitogen activated protein kinase 13
3968 26409 AI427174 mitogen activated protein kinase kinase kinase 7
4936 26414 AI385708 mitogen-activated protein kinase 10
4597 18555 AI327059 PCTAIRE-motif protein kinase 1
28130 18557 AI323675 PCTAIRE-motif protein kinase 3
32033 20112 AI448582 ribosomal protein S6 kinase, 90 kD, polypeptide 2
22845 20779 AI413783 Rous sarcoma oncogene
10154 21754 AI449716 testis specific protein kinase 1
34216 22241 AI414377 Unc-51 like kinase 1 (C. elegans)
8108 22390 AI465227 wee 1 homolog (S. pombe)
cell growth and/or maintenance
7883 11789 AI451571 adenomatosis polyposis coli 0.217
8534 13649 AI427644 epidermal growth factor receptor
1424 14042 AI385657 exostoses (multiple) 1
20964 14681 AI661491 guanine nucleotide binding protein, alpha o
3510 16326 AI452079 inhibin beta E
142 16818 AI573454 lymphocyte protein tyrosine kinase
880 16341 AI323816 mammary tumor integration site 6
734 18176 AI414879 neuroblastoma ras oncogene
757 11848 AI324087 ras homolog A2
304 19645 AI323835 retinoblastoma 1
28027 19651 AI323872 retinoblastoma-like 2
22845 20779 AI413783 Rous sarcoma oncogene
22670 17246 AI448103 transformed mouse 3T3 cell double minute 2
30435 22084 AI450392 tuberous sclerosis 2
28230 17134 AI428545 v-maf musculoaponeurotic fibrosarcoma oncogene family,
protein G (avian)
cell adhesion
27291 53414 AI326786 Bystin-like 0.274
4911 12805 AI425965 Contactin 1
4851 13805 AI414256 Endoglin
1346 16401 AI450152 Integrin alpha 4
27448 18186 AI323974 Neuropilin
46724 58998 AI428160 Poliovirus receptor-related 3
738 12826 AI528741 Procollagen, type IV, alpha 1
22173 20345 AI661333 Selectin, platelet (p-selectin) ligand
980 21923 AI327207 Tenascin C
14455 21810 AI661287 Transforming growth factor, beta induced, 68 kDa
18994 56321 AI426755 Traube
3758 12927 AI426143 V-crk-associated tyrosine kinase substrate
metabolism
80501 11982 AI327378 ATPase, class V, type 10A 0.058
14926 11977 AI449437 ATPase, Cu++ transporting, alpha polypeptide
25848 12039 AI323918 Branched chain ketoacid dehydrogenase E1, alpha
polypeptide
26940 12408 AI323923 Carbonyl reductase 1
10172 13017 AI326235 C-terminal binding protein 2
19987 13190 AI325230 Dopachrome tautomerase
2820 14635 AI894127 Galactokinase
29751 56454 AI324071 Pyrroline-5-carboxylate synthetase (glutamate
gamma-semialdehyde synthetase)
28393 20751 AI894147 Sepiapterin reductase
6611 26458 AI326155 Solute carrier family 27 (fatty acid transporter),
member 2
5129 20905 AI430879 Steroid sulfatase
transport
15691 11307 AI323653 ATP-binding cassette, sub-family G (WHITE), member 1 0.257
29133 12236 AI465548 Budding uninhibited by benzimidazoles 1 homolog, beta
(S. cerevisiae)
3049 54124 AI326913 CDC28 protein kinase 1
7417 12445 AI323871 Cyclin D3
118 12566 AI323666 Cyclin-dependent kinase 2
168789 12577 AI428384 Cyclin-dependent kinase inhibitor 1C (P57)
3292 14810 AI385669 Glutamate receptor, ionotropic, NMDA1 (zeta 1)
31625 17339 AI323353 Major intrinsic protein of eye lens fiber
27970 26415 AI894223 Mitogen activated protein kinase 13
12145 19646 AI324260 Retinoblastoma binding protein 4
28027 19651 AI323872 Retinoblastoma-like 2
apoptosis
692 11800 AI661160 apoptosis inhibitor 5 0.169
17493 12905 AI426523 CASP2 and RIPK1 domain containing adaptor with death
domain
28814 12368 AI326797 caspase 6
10026 14311 AI323465 fat specific gene 27
22216 14605 AI326808 glucocorticoid-induced leucine zipper
1715 16994 AI327398 lymphotoxin B
143798 58801 AI449135 phorbol-12-myristate-13-acetate-induced protein 1
544 18611 AI323543 phosphoprotein enriched in astrocytes 15
32801 70527 AI662639 Stam binding protein
29351 21842 AI425932 TGF-beta1-induced anti-apoptotic factor 1
cell cycle
2450 19659 AI893623 Retinol binding protein 1, cellular 0.28
2605 19662 AI326915 Retinol binding protein 4, plasma
157511 20516 AI415416 Solute carrier family 20, member 2
17322 20518 AI428862 Solute carrier family 22 (organic cation transporter),
member 2
29510 59023 AI413193 Solute carrier family 28 (sodium-coupled nucleoside
transporter), member 2
18300 20532 AI451127 Solute carrier family 3, member 1
2446 20983 AI323609 Synaptotagmin 4
15755 20466 AI426974 Transcriptional regulator, SIN3A (yeast)
2137 20467 AI327204 Transcriptional regulator, SIN3B (yeast)
2108 22139 AI323822 Transthyretin
signal transduction
4316 11863 AI451564 aryl hydrocarbon receptor nuclear translocator 0.263
17493 12905 AI426523 CASP2 and RIPK1 domain containing adaptor with death
domain
12895 20299 AI449147 chemokine (C-C motif) ligand 22
32472 14169 AI451464 fibroblast growth factor 14
6577 53612 AI448040 PCTAIRE-motif protein kinase 3
10723 18628 AI428816 period homolog 3 (Drosophila)
23978 23970 AI662563 protein kinase C and casein kinase substrate in
neurons2
20945 67903 AI429553 regulator of G-protein signaling 19 interacting
protein1
8249 20846 AI449540 signal transducer and activator of transcription 1
protein biosynthesis
2050 66480 AI465224 eukaryotic translation initiation factor 3, subunit 6 0.35
22147 56055 AI450198 GTP binding protein 2
70127 19897 AI323900 hypothetical pseudogene ribosomal protein L12
880 16341 AI323816 mammary tumor integration site 6
142380 26451 AI415314 ribosomal protein L27a
11376 54217 AI464570 ribosomal protein L36
5291 20103 AI464376 ribosomal protein S5
140568 68436 AI894275 RIKEN cDNA 1100001I22 gene
27419 69606 AI450131 RIKEN cDNA 2310020P08 gene
G-protein coupled receptor protein signaling pathway*
153916 11540 AI465291 adenosine A2a receptor 0.014
12948 14065 AI413964 coagulation factor II (thrombin) receptor-like 3
32191 54393 AI449538 gamma-aminobutyric acid (GABA-B) receptor, 1
989 14672 AI528620 guanine nucleotide binding protein, alpha 11
202311 14674 AI426467 guanine nucleotide binding protein, alpha 13
20964 14681 AI661491 guanine nucleotide binding protein, alpha o
30141 14693 AI448892 guanine nucleotide binding protein, beta 2
4463 22355 AI385741 vasoactive intestinal peptide receptor 2
cell cycle control
7417 12445 AI323871 cyclin D3 0.431
8534 13649 AI427644 epidermal growth factor receptor
734 18176 AI414879 neuroblastoma ras oncogene
2675 18590 AI385687 platelet derived growth factor, alpha
22845 20779 AI413783 Rous sarcoma oncogene
18213 21808 AI323791 transforming growth factor, beta 2
31540 22339 AI450411 vascular endothelial growth factor A
28230 17134 AI428545 v-maf musculoaponeurotic fibrosarcoma oncogene family,
protein G (avian)
intracellular signaling cascade
16009 16428 AI528630 IL2-inducible T-cell kinase 0.142
1781 16822 AI451618 lymphocyte cytosolic protein 2
142 16818 AI573454 lymphocyte protein tyrosine kinase
544 18611 AI323543 phosphoprotein enriched in astrocytes 15
22845 20779 AI413783 Rous sarcoma oncogene
8249 20846 AI449540 signal transducer and activator of transcription 1
33824 76561 AI450660 sorting nexin 7
intracellular protein traffic
6836 11840 AI324265 ADP-ribosylation factor 1 0.102
196526 11845 AI449299 ADP-ribosylation factor 6
16710 16211 AI323858 karyopherin (importin) beta 1
28375 53421 AI327023 SEC61, alpha subunit (S. cerevisiae)
33824 76561 AI450660 sorting nexin 7
27393 21855 AI429549 translocator of inner mitochondrial membrane b
electron transport
43415 12861 AI893442 cytochrome c oxidase, subunit VI a, polypeptide 1 0.234
14022 12868 AI326932 cytochrome c oxidase, subunit VIIIa
14781 13086 AI893559 cytochrome P450, family 2, subfamily a, polypeptide 4
21758 13106 AI323829 cytochrome P450, family 2, subfamily e, polypeptide 1
20115 13142 AI447515 D-amino acid oxidase
3533 56551 AI325495 thioredoxin 2 0.343
defense response
6417 12484 AI323855 CD24a antigen
22564 14969 AI447932 histocompatibility 2, class II antigen E beta
7043 16149 AI451110 Ia-associated invariant chain
41980 17086 AI450786 natural cytotoxicity triggering receptor 1
33874 142980 AI450647 toll-like receptor 3
154045 56753 AI426251 tumor-associated calcium signal transducer 2
heat shock response*
21549 80888 AI326838 Cryac Crystallin, alpha C 0.035
2982 81489 AI465465 Dnajb1 DnaJ (Hsp40) homolog, subfamily B, member 1
197601 15528 AI327085 Hspe1 Heat shock 10 kDa protein 1 (chaperonin 10)
22708 12406 AI326777 Serpinh1 Serine (or cysteine) proteinase inhibitor,
clade H (heat shock protein 47), member 1
histogenesis and organogenesis
10663 17172 AI415258 achaete-scute complex homolog-like 1 (Drosophila) 0.49
27757 12153 AI327151 bone morphogenetic protein 1
215 15414 AI385768 homeo box B6
26544 15438 AI385671 homeo box D9
immune response
12895 20299 AI449147 chemokine (C-C motif) ligand 22 0.317
22564 14969 AI447932 histocompatibility 2, class II antigen E beta
18530 15950 AI661257 interferon activated gene 203
AI451137
1715 16994 AI327398 lymphotoxin B
post-translational membrane targeting
6417 12484 AI323855 CD24a antigen 0.219
4911 12805 AI425965 contactin 1
1098 53872 AI323833 GPI-anchored membrane protein 1
1514 16956 AI326787 lipoprotein lipase
sensory organ development*
22830 12957 AI325927 Cryba1 Crystallin, beta A1 0.035
86656 12958 AI324706 Cryba2 Crystallin, beta A2
30374 12966 AI323924 Crygc Crystallin, gamma C
20176 12964 AI323909 Mus musculus crystallin, gamma A (Cryga), mRNA
small GTPase mediated signal transduction
196526 11845 AI449299 ADP-ribosylation factor 6 0.422
24443 14569 AI528719 guanosine diphosphate (GDP) dissociation inhibitor 3
734 18176 AI414879 neuroblastoma ras oncogene
757 11848 AI324087 ras homolog gene family, member A
ubiquitin-dependent protein degradation
30097 26440 AI325451 proteasome (prosome, macropain) subunit, alpha type 1 0.445
368 19172 AI415623 proteasome (prosome, macropain) subunit, beta type 4
9002 22215 AI661496 ubiquitin protein ligase E3A
29352 22213 AI413443 ubiquitin-conjugating enzyme E2G 2
cation transport
80501 11982 AI327378 ATPase, Class V, type 10A 0.475
14926 11977 AI449437 ATPase, Cu++ transporting, alpha polypeptide
23020 16530 AI414909 potassium channel, subfamily K, member 7
cell cycle arrest
168789 12577 AI428384 cyclin-dependent kinase inhibitor 1C (P57) 0.167
7549 13198 AI323295 DNA-damage inducible transcript 3
3350 11426 AI449659 microtubule-actin crosslinking factor 1
DNA replication
29361 50793 AI427116 origin recognition complex, subunit 3-like (S. 0.422
cerevisiae)
9199 18974 AI451438 polymerase (DNA directed), epsilon 2 (p59 subunit)
12145 19646 AI324260 retinoblastoma binding protein 4
embryogenesis and morphogenesis
27757 12153 AI327151 bone morphogenetic protein 1 0.317
7320 17127 AI324173 MAD homolog 3 (Drosophila)
100399 17128 AI427147 MAD homolog 4 (Drosophila)
mitosis
29133 12236 AI465548 budding uninhibited by benzimidazoles 1 homolog, beta 0.239
(S. cerevisiae)
118 12566 AI323666 cyclin-dependent kinase 2
8108 22390 AI465227 wee 1 homolog (S. pombe)
proteolysis and peptidolysis*
27757 12153 AI327151 bone morphogenetic protein 1 0.018
28814 12368 AI326797 caspase 6
21306 17391 AI426335 matrix metalloproteinase 24
ribosome biogenesis
70127 19897 AI323900 hypothetical pseudogene ribosomal protein L12 0.056
5291 20103 AI464376 ribosomal protein S5
32033 20112 AI448582 ribosomal protein S6 kinase, polypeptide 2
synaptic transmission
32191 54393 AI449538 gamma-aminobutyric acid (GABA-B) receptor, 1 0.167
3292 14810 AI385669 glutamate receptor, ionotropic, NMDA1 (zeta 1)
23020 16530 AI414909 potassium channel, subfamily K, member 7
transcription regulation, from Pol II promoter
29275 56787 AI415295 achaete-scute complex homolog-like 3 (Drosophila) 0.105
3909 20585 AI327369 SWI/SNF related, matrix associated, actin dependent
regulator of chromatin, subfamily a, member 3
15781 22282 AI893650 upstream transcription factor 2
anti-apoptosis
692 11800 AI661160 apoptosis inhibitor 5 0.263
22216 14605 AI326808 glucocorticoid-induced leucine zipper
carbohydrate metabolism
2040 12091 AI528555 galactosidase, beta 1 0.38
103675 50720 AI451106 ribonucleotide reductase M2
cell-matrix adhesion
1346 16401 AI450152 integrin alpha 4 0.171
757 11848 AI324087 ras homolog gene family, member A
common-partner SMAD protein phosphorylation
7320 17127 AI324173 MAD homolog 3 (Drosophila) 0.093
100399 17128 AI427147 MAD homolog 4 (Drosophila)
cytoskeleton organization and biogenesis
1000 17901 AI324023 myosin light chain, alkali, fast skeletal muscle 0.453
4010 22349 AI414231 villin
DNA repair
28619 23894 AI327310 general transcription factor II H, polypeptide 2 0.453
12145 19646 AI324260 retinoblastoma binding protein 4
glycolysis
7729 11676 AI327146 aldolase 3, C isoform 0.171
29994 13808 AI325234 enolase 3, beta muscle
hydrogen transport
20869 11975 AI451534 ATPase, H+ transporting lysosomal V0 subunit a isoform1 0.093
30155 11984 AI385732 ATPase, H+ transporting, V0 subunit C
induction of apoptosis
28814 12368 AI326797 caspase 6 0.171
143798 58801 AI449135 phorbol-12-myristate-13-acetate-induced protein 1
integrin-mediated signaling pathway
1346 16401 AI450152 integrin alpha 4 0.359
757 11848 AI324087 ras homolog gene family, member A
mRNA splicing
6787 20383 AI528616 splicing factor, arginine/serine-rich 3 (SRp20) 0.105
28150 81898 AI666563 splicing factor 3b, subunit 1
microtubule-based movement
29317 56444 AI326428 ARP10 actin-related protein 10 homolog (S. cerevisiae) 0.359
19726 13411 AI326265 dynein, axonemal, heavy chain 11
microtubule-based process
86654 17760 AI448037 microtubule-associated protein 6 0.077
1948 21648 AI465254 t-complex testis expressed 1
neurogenesis
10663 17172 AI415258 achaete-scute complex homolog-like 1 (Drosophila) 0.252
3507 18227 AI429298 nuclear receptor subfamily 4, group A, member 2
protein folding
28480 30795 AI427165 FK506 binding protein 3 0.38
197601 15528 AI327085 heat shock protein 1 (chaperonin 10)
pattern specification
215 15414 AI385768 homeo box B6 0.093
26544 15438 AI385671 homeo box D9
potassium transport
424 11933 AI450702 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.459
23020 16530 AI414909 potassium channel, subfamily K, member 7
protein kinase cascade*
202311 14674 AI426467 guanine nucleotide binding protein, alpha 13 0.035
29857 64011 AI326818 neurogranin
protein modification
20874 18602 AI666339 peptidyl arginine deiminase, type IV 0.359
9002 22215 AI661496 ubiquitin protein ligase E3A
RHO protein signal transduction
202311 14674 AI426467 guanine nucleotide binding protein, alpha 13 0.093
757 11848 AI324087 ras homolog gene family, member A
RNA processing
16767 53379 AI449004 heterogeneous nuclear ribonucleoprotein A2/B1 0.263
111 18521 AI893657 poly(rC) binding protein 2
actin cytoskeleton organization and biogenesis
3529 12343 AI528740 capping protein (actin filament) muscle Z-line, alpha 2 0.288
action potential regulation
989 14672 AI528620 guanine nucleotide binding protein, alpha 11 0.05
amino acid biosynthesis*
29751 56454 AI324071 pyrroline-5-carboxylate synthetase (glutamate 0.035
gamma-semialdehyde synthetase)
angiogenesis
202311 14674 AI426467 guanine nucleotide binding protein, alpha 13 0.05
anion transport
569 22334 AI430965 voltage-dependent anion channel 2 0.05
ATP biosynthesis
30155 11984 AI385732 ATPase, H+ transporting, V0 subunit C 0.288
base conversion/substitution editing
153899 56417 AI449308 adenosine deaminase, RNA-specific 0.05
biosynthesis
27419 69606 AI450131 RIKEN cDNA 2310020P08 gene 0.288
cell communication
26859 14622 AI323309 gap junction membrane channel protein beta 5 0.159
cell differentiation
202311 14674 AI426467 guanine nucleotide binding protein, alpha 13 0.159
cell growth
18213 21808 AI323791 transforming growth factor, beta 2 0.05
cell proliferation
4078 17345 AI428398 antigen identified by monoclonal antibody Ki 67 0.47
cell shape control
202311 14674 AI426467 guanine nucleotide binding protein, alpha 13 0.159
cell-cell signaling
26859 14622 AI323309 gap junction membrane channel protein beta 5 0.288
cellular defense response
30557 21473 AI449302 T-cell receptor alpha chain 0.288
central nervous system development
9524 17684 AI430768 Cbp/p300-interacting transactivator, with Glu/Asp-rich 0.05
carboxy-terminal domain, 2
chemotaxis
12895 20299 AI449147 chemokine (C-C motif) ligand 22 0.47
cholesterol metabolism
28099 20652 AI385523 sterol O-acyltransferase 1 0.05
chromatin assembly/disassembly
28003 12419 AI893653 chromobox homolog 5 (Drosophila HP1a) 0.288
chromatin modeling
29546 56456 AI447773 BRG1/brm-associated factor 53A 0.05
chromosome organization and biogenesis (sensu Eukarya)
193557 15269 AI323498 similar to germinal histone H4 gene 0.47
copper ion transport
14926 11977 AI449437 ATPase, Cu++ transporting, alpha polypeptide 0.05
cytokine and chemokine mediated signaling pathway
103809 58184 AI414253 rcd1 (required for cell differentiation) homolog 1 0.159
(S. pombe)
detoxification response
4316 11863 AI451564 aryl hydrocarbon receptor nuclear translocator 0.05
developmental processes
4524 16825 AI465231 LIM domain binding 1 0.224
DNA dependent DNA replication
214703 117599 AI451189 helicase (DNA) B 0.05
DNA methylation
322 17191 AI449099 methyl-CpG binding domain protein 2 0.288
DNA modification
20915 21976 AI428343 topoisomerase (DNA) III beta 0.05
DNA packaging
2756 15312 AI426113 similar to nonhistone chromosomal protein HMG-14 - 0.415
mouse
DNA replication, priming
214703 117599 AI451189 helicase (DNA) B 0.159
DNA topological change
20915 21976 AI428343 topoisomerase (DNA) III beta 0.05
DNA unwinding
20915 21976 AI428343 topoisomerase (DNA) III beta 0.05
dopamine receptor signaling pathway
20964 14681 AI661491 guanine nucleotide binding protein, alpha o 0.05
endoderm development
1424 14042 AI385657 exostoses (multiple) 1 0.05
fatty acid metabolism
6611 26458 AI326155 solute carrier family 27 (fatty acid transporter), 0.47
member 2
galactose metabolism
2820 14635 AI894127 galactokinase 1 0.05
gastrulation
1424 14042 AI385657 exostoses (multiple) 1 0.05
glutamate signaling pathway
989 14672 AI528620 guanine nucleotide binding protein, alpha 11 0.05
glutathione biosynthesis
4559 14598 AI323672 gamma-glutamyltransferase 1 0.05
glutathione metabolism
4559 14598 AI323672 gamma-glutamyltransferase 1 0.05
G-protein signaling, adenylate cyclase activating pathway
153916 11540 AI465291 adenosine A2a receptor 0.159
heart development
989 14672 AI528620 guanine nucleotide binding protein, alpha 11 0.05
heavy metal ion transport
14926 11977 AI449437 ATPase, Cu++ transporting, alpha polypeptide 0.159
heparan sulfate proteoglycan metabolism
103788 27029 AI464451 calbindin 1, 28 kDa 0.05
humoral immune response
138544 16121 AI450390 immunoglobulin kappa chain variable 4 (V4) 0.415
inflammatory response
12895 20299 AI449147 chemokine (C-C motif) ligand 22 0.288
ion transport
3292 14810 AI385669 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.202
ionic insulation of neurons by glial cells
1268 18823 AI323793 proteolipid protein 1 (Pelizaeus-Merzbacher disease, 0.05
spastic paraplegia 2, uncomplicated)
iron homeostasis
7500 14325 AI449517 ferritin light chain 1 0.159
iron transport
7500 14325 AI449517 ferritin light chain 1 0.159
JAK-STAT cascade
38869 56469 AI448242 protein inhibitor of activated STAT 1 0.05
lipid catabolism
1514 16956 AI326787 lipoprotein lipase 0.47
lipid metabolism
1514 16956 AI326787 lipoprotein lipase 0.415
lipid transport
1514 16956 AI326787 lipoprotein lipase 0.288
locomotory behavior
20964 14681 AI661491 guanine nucleotide binding protein, alpha o 0.159
lymph gland development
1715 16994 AI327398 lymphotoxin B 0.415
lysosomal lumen acidification
30155 11984 AI385732 ATPase, H+ transporting, V0 subunit C 0.05
melanin biosynthesis, from tyrosine
19987 13190 AI325230 ATPase, Cu++ transporting, alpha polypeptide 0.05
mercury ion transport
14926 11977 AI449437 ATPase, Cu++ transporting, alpha polypeptide 0.05
mesoderm development
1424 14042 AI385657 exostoses (multiple) 1 0.05
metabotropic glutamate receptor signaling pathway
10022 26558 AI327089 homer homolog 3 (Drosophila) 0.159
mitotic cycle control
18994 56321 AI426755 apoptosis antagonizing transcription factor 0.05
mRNA processing
28150 81898 AI666563 splicing factor 3b, subunit 1 0.159
mRNA splice site selection
6787 20383 AI528616 splicing factor, arginine/serine-rich 3 (SRp20) 0.415
muscle contraction regulation
35134 11937 AI324248 ATPase, Ca++ transporting, cardiac muscle, fast twitch1 0.288
muscle development
1000 17901 AI324023 myosin light chain, alkali, fast skeletal muscle 0.415
neuroblast determination
10663 17172 AI415258 achaete-scute complex homolog-like 1 (Drosophila) 0.05
nitrogen fixation
2338 14645 AI413315 glutamate-ammonia ligase (glutamine synthase) 0.159
nucleosome assembly
193557 15269 AI323498 similar to germinal histone H4 gene 0.288
one-carbon compound metabolism
3379 20425 AI452103 serine hydroxymethyl transferase 1 (soluble) 0.05
ossification
27757 12153 AI327151 bone morphogenetic protein 1 0.05
oxygen transport*
30266 15129 AI323916 Hbb-b1 hemoglobin, beta adult major chain 0.023
peptide hormone processing
4881 30052 AI604765 proprotein convertase subtilisin/kexin type 1 inhibitor 0.05
peptide metabolism*
5121 18484 AI323455 peptidylglycine alpha-amidating monooxygenase 0.035
peroxisome organization and biogenesis
20901 18632 AI596335 peroxisomal biogenesis factor 11b 0.47
phototransduction
12925 18582 AI414297 phosphodiesterase 6D, cGMP-specific, rod, delta 0.159
proline biosynthesis
29751 56454 AI324071 pyrroline-5-carboxylate synthetase (glutamate 0.05
gamma-semialdehyde synthetase)
protein amino acid ADP-ribosylation
2816 11875 AI323430 ADP-ribosyltransferase 5 0.159
protein amino acid dephosphorylation
20253 54384 AI327236 myotubularin related protein 7 0.055
protein amino acid glycosylation
10701 20452 AI385627 sialyltransferase 8 (alpha-2, 8-sialyltransferase) D 0.159
protein metabolism and modification
22271 80886 AI596338 similar to smt3-specific isopeptidase 1; 0.159
sentrin/SUMO-specific protease
protein secretion
28375 53421 AI327023 SEC61, alpha subunit (S. cerevisiae) 0.288
protein transport
27393 21855 AI429549 translocator of inner mitochondrial membrane b 0.371
protein-nucleus import, docking
16710 16211 AI323858 karyopherin (importin) beta 1 0.159
purine nucleoside transport
29510 59023 AI413193 solute carrier family 28 (sodium-coupled nucleoside 0.05
transporter), member 2
RAS protein signal transduction
734 18176 AI414879 neuroblastoma ras oncogene 0.371
receptor mediated endocytosis
2735 65969 AI661835 SWI/SNF related, matrix associated, actin dependent 0.05
regulator of chromatin, subfamily d, member 1
regulation of body size
4132 12701 AI464459 suppressor of cytokine signaling 2 0.159
regulation of cell migration
2453 20604 AI326805 somatostatin 0.05
retinoid metabolism
2450 19659 AI893623 retinol binding protein 1, cellular 0.05
rhythmic behavior
10723 18628 AI428816 period homolog 3 (Drosophila) 0.05
skeletal development
989 14672 AI528620 guanine nucleotide binding protein, alpha 11 0.05
SMAD protein heteromerization
7320 17127 AI324173 MAD homolog 3 (Drosophila) 0.159
SMAD protein nuclear translocation*
100399 17128 AI427147 MAD homolog 4 (Drosophila) 0.05
sodium transport
424 11933 AI450702 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.288
spermatogenesis
4559 14598 AI323672 gamma-glutamyltransferase 1 0.371
steroid biosynthesis
28099 20652 AI385523 sterol O-acyltransferase 1 0.159
steroid metabolism
5129 20905 AI430879 steroid sulfatase 0.05
transcription
27375 17749 AI661386 metallothionein-I activator 0.159
transmembrane receptor protein tyrosine kinase signaling pathway
8534 13649 AI427644 epidermal growth factor receptor 0.415
ubiquitin cycle
9002 22215 AI661496 ubiquitin protein ligase E3A 0.415
vacuolar acidification
30155 11984 AI385732 ATPase, H+ transporting, V0 subunit C 0.05
very long chain fatty acid metabolism
2567 54326 AI448451 elongation of very long chain fatty acids (FEN1/Elo2, 0.05
SUR4/Elo3, yeast)-like 2
water transport
40333 11831 AI452338 aquaporin 6 0.159
Wnt receptor signaling pathway
7883 11789 AI451571 adenomatosis polyposis coli 0.05
xenobiotic metabolism
22637 64296 AI661482 RIKEN cDNA 0910001L24 gene 0.05
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