Table 2 of
Wride, Mol Vis 2003;
9:360-396.
Table 2. Onto-ExpressTM analysis of the 1,668 genes expressed at above background plus 2 SD levels in at least one of the lens samples
Results of Onto-ExpressTM analysis of the 1,668 genes expressed at above background plus 2 SD levels in at least one of the lens samples to determine the biological processes in which they are involved according to Gene OntologyTM. The genes are listed in their categories in descending order of number of genes per category. P values are calculated by Onto-ExpressTM by comparing the proportion of genes in a given category identified using the microarray with the total complement of genes in that category on the array. Thereby, groups of genes with smaller p values are represented in the microarray data in greater numbers than would be expected (transcription factors p=0.047; G-Protein Coupled Receptor Signaling Pathway p=0.014). Categories with p<0.05 are labeled with an asterisk ("*"). Genes may appear in more than one category if they have more than one GeneOntologyTM term associated with them.
Biological Cluster Locus Accession process ID ID number(s) Gene name p value ----------------- ------- ------ --------- ------------------------------------------------------- ------- transcription regulation* 4316 11863 AI451564 aryl hydrocarbon receptor nuclear translocator 0.047 9524 17684 AI430768 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 7549 13198 AI323295 DNA-damage inducible transcript 3 4303 14056 AI323840 enhancer of zeste homolog 2 (Drosophila) 28619 23894 AI327310 general transcription factor II H, polypeptide 2 (44 kDa subunit) 29630 14887 AI429623 general transcription factor III C 1 22216 14605 AI326808 glucocorticoid-induced leucine zipper 215 15414 AI385768 homeo box B6 26544 15438 AI385671 homeo box D9 7320 17127 AI324173 MAD homolog 3 (Drosophila) 100399 17128 AI427147 MAD homolog 4 (Drosophila) 10563 17765 AI448197 metal response element binding transcription factor 2 101277 29861 AI430751 neuronal d4 domain family member 6549 17937 AI385556 Ngfi-A binding protein 2 4918 14815 AI447752 nuclear receptor subfamily 3, group C, member 1 3507 18227 AI429298 nuclear receptor subfamily 4, group A, member 2 27220 18046 AI448923 nuclear transcription factor-Y gamma 10723 18628 AI428816 period homolog 3 (Drosophila) 304 19645 AI323835 retinoblastoma 1 28027 19651 AI323872 retinoblastoma-like 2 4081 12394 AI451932 runt related transcription factor 1 8249 20846 AI449540 signal transducer and activator of transcription 1 21642 20728 AI451311 Spi-C transcription factor (Spi-1/PU.1 related) 4605 21385 AI448932 T-box 2 103636 21388 AI464523 T-box 5 3406 21423 AI324257 transcription factor E2a 15755 20466 AI426974 transcriptional regulator, SIN3A (yeast) 2137 20467 AI327204 transcriptional regulator, SIN3B (yeast) 15781 22282 AI893650 upstream transcription factor 2 28230 17134 AI428545 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) 3868 22632 AI447233 YY1 transcription factor protein amino acid phosphorylation 29133 12236 AI465548 budding uninhibited by benzimidazoles 1 homolog, beta 0.286 (S. cerevisiae) 30199 27373 AI449651 casein kinase 1, epsilon 18268 12748 AI661472 CDC-like kinase 2 118 12566 AI323666 cyclin-dependent kinase 2 8534 13649 AI427644 epidermal growth factor receptor 25120 26559 AI426929 hormonally upregulated Neu-associated kinase 16009 16428 AI528630 IL2-inducible T-cell kinase 142 16818 AI573454 lymphocyte protein tyrosine kinase 27970 26415 AI894223 mitogen activated protein kinase 13 3968 26409 AI427174 mitogen activated protein kinase kinase kinase 7 4936 26414 AI385708 mitogen-activated protein kinase 10 4597 18555 AI327059 PCTAIRE-motif protein kinase 1 28130 18557 AI323675 PCTAIRE-motif protein kinase 3 32033 20112 AI448582 ribosomal protein S6 kinase, 90 kD, polypeptide 2 22845 20779 AI413783 Rous sarcoma oncogene 10154 21754 AI449716 testis specific protein kinase 1 34216 22241 AI414377 Unc-51 like kinase 1 (C. elegans) 8108 22390 AI465227 wee 1 homolog (S. pombe) cell growth and/or maintenance 7883 11789 AI451571 adenomatosis polyposis coli 0.217 8534 13649 AI427644 epidermal growth factor receptor 1424 14042 AI385657 exostoses (multiple) 1 20964 14681 AI661491 guanine nucleotide binding protein, alpha o 3510 16326 AI452079 inhibin beta E 142 16818 AI573454 lymphocyte protein tyrosine kinase 880 16341 AI323816 mammary tumor integration site 6 734 18176 AI414879 neuroblastoma ras oncogene 757 11848 AI324087 ras homolog A2 304 19645 AI323835 retinoblastoma 1 28027 19651 AI323872 retinoblastoma-like 2 22845 20779 AI413783 Rous sarcoma oncogene 22670 17246 AI448103 transformed mouse 3T3 cell double minute 2 30435 22084 AI450392 tuberous sclerosis 2 28230 17134 AI428545 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) cell adhesion 27291 53414 AI326786 Bystin-like 0.274 4911 12805 AI425965 Contactin 1 4851 13805 AI414256 Endoglin 1346 16401 AI450152 Integrin alpha 4 27448 18186 AI323974 Neuropilin 46724 58998 AI428160 Poliovirus receptor-related 3 738 12826 AI528741 Procollagen, type IV, alpha 1 22173 20345 AI661333 Selectin, platelet (p-selectin) ligand 980 21923 AI327207 Tenascin C 14455 21810 AI661287 Transforming growth factor, beta induced, 68 kDa 18994 56321 AI426755 Traube 3758 12927 AI426143 V-crk-associated tyrosine kinase substrate metabolism 80501 11982 AI327378 ATPase, class V, type 10A 0.058 14926 11977 AI449437 ATPase, Cu++ transporting, alpha polypeptide 25848 12039 AI323918 Branched chain ketoacid dehydrogenase E1, alpha polypeptide 26940 12408 AI323923 Carbonyl reductase 1 10172 13017 AI326235 C-terminal binding protein 2 19987 13190 AI325230 Dopachrome tautomerase 2820 14635 AI894127 Galactokinase 29751 56454 AI324071 Pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde synthetase) 28393 20751 AI894147 Sepiapterin reductase 6611 26458 AI326155 Solute carrier family 27 (fatty acid transporter), member 2 5129 20905 AI430879 Steroid sulfatase transport 15691 11307 AI323653 ATP-binding cassette, sub-family G (WHITE), member 1 0.257 29133 12236 AI465548 Budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 3049 54124 AI326913 CDC28 protein kinase 1 7417 12445 AI323871 Cyclin D3 118 12566 AI323666 Cyclin-dependent kinase 2 168789 12577 AI428384 Cyclin-dependent kinase inhibitor 1C (P57) 3292 14810 AI385669 Glutamate receptor, ionotropic, NMDA1 (zeta 1) 31625 17339 AI323353 Major intrinsic protein of eye lens fiber 27970 26415 AI894223 Mitogen activated protein kinase 13 12145 19646 AI324260 Retinoblastoma binding protein 4 28027 19651 AI323872 Retinoblastoma-like 2 apoptosis 692 11800 AI661160 apoptosis inhibitor 5 0.169 17493 12905 AI426523 CASP2 and RIPK1 domain containing adaptor with death domain 28814 12368 AI326797 caspase 6 10026 14311 AI323465 fat specific gene 27 22216 14605 AI326808 glucocorticoid-induced leucine zipper 1715 16994 AI327398 lymphotoxin B 143798 58801 AI449135 phorbol-12-myristate-13-acetate-induced protein 1 544 18611 AI323543 phosphoprotein enriched in astrocytes 15 32801 70527 AI662639 Stam binding protein 29351 21842 AI425932 TGF-beta1-induced anti-apoptotic factor 1 cell cycle 2450 19659 AI893623 Retinol binding protein 1, cellular 0.28 2605 19662 AI326915 Retinol binding protein 4, plasma 157511 20516 AI415416 Solute carrier family 20, member 2 17322 20518 AI428862 Solute carrier family 22 (organic cation transporter), member 2 29510 59023 AI413193 Solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 18300 20532 AI451127 Solute carrier family 3, member 1 2446 20983 AI323609 Synaptotagmin 4 15755 20466 AI426974 Transcriptional regulator, SIN3A (yeast) 2137 20467 AI327204 Transcriptional regulator, SIN3B (yeast) 2108 22139 AI323822 Transthyretin signal transduction 4316 11863 AI451564 aryl hydrocarbon receptor nuclear translocator 0.263 17493 12905 AI426523 CASP2 and RIPK1 domain containing adaptor with death domain 12895 20299 AI449147 chemokine (C-C motif) ligand 22 32472 14169 AI451464 fibroblast growth factor 14 6577 53612 AI448040 PCTAIRE-motif protein kinase 3 10723 18628 AI428816 period homolog 3 (Drosophila) 23978 23970 AI662563 protein kinase C and casein kinase substrate in neurons2 20945 67903 AI429553 regulator of G-protein signaling 19 interacting protein1 8249 20846 AI449540 signal transducer and activator of transcription 1 protein biosynthesis 2050 66480 AI465224 eukaryotic translation initiation factor 3, subunit 6 0.35 22147 56055 AI450198 GTP binding protein 2 70127 19897 AI323900 hypothetical pseudogene ribosomal protein L12 880 16341 AI323816 mammary tumor integration site 6 142380 26451 AI415314 ribosomal protein L27a 11376 54217 AI464570 ribosomal protein L36 5291 20103 AI464376 ribosomal protein S5 140568 68436 AI894275 RIKEN cDNA 1100001I22 gene 27419 69606 AI450131 RIKEN cDNA 2310020P08 gene G-protein coupled receptor protein signaling pathway* 153916 11540 AI465291 adenosine A2a receptor 0.014 12948 14065 AI413964 coagulation factor II (thrombin) receptor-like 3 32191 54393 AI449538 gamma-aminobutyric acid (GABA-B) receptor, 1 989 14672 AI528620 guanine nucleotide binding protein, alpha 11 202311 14674 AI426467 guanine nucleotide binding protein, alpha 13 20964 14681 AI661491 guanine nucleotide binding protein, alpha o 30141 14693 AI448892 guanine nucleotide binding protein, beta 2 4463 22355 AI385741 vasoactive intestinal peptide receptor 2 cell cycle control 7417 12445 AI323871 cyclin D3 0.431 8534 13649 AI427644 epidermal growth factor receptor 734 18176 AI414879 neuroblastoma ras oncogene 2675 18590 AI385687 platelet derived growth factor, alpha 22845 20779 AI413783 Rous sarcoma oncogene 18213 21808 AI323791 transforming growth factor, beta 2 31540 22339 AI450411 vascular endothelial growth factor A 28230 17134 AI428545 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) intracellular signaling cascade 16009 16428 AI528630 IL2-inducible T-cell kinase 0.142 1781 16822 AI451618 lymphocyte cytosolic protein 2 142 16818 AI573454 lymphocyte protein tyrosine kinase 544 18611 AI323543 phosphoprotein enriched in astrocytes 15 22845 20779 AI413783 Rous sarcoma oncogene 8249 20846 AI449540 signal transducer and activator of transcription 1 33824 76561 AI450660 sorting nexin 7 intracellular protein traffic 6836 11840 AI324265 ADP-ribosylation factor 1 0.102 196526 11845 AI449299 ADP-ribosylation factor 6 16710 16211 AI323858 karyopherin (importin) beta 1 28375 53421 AI327023 SEC61, alpha subunit (S. cerevisiae) 33824 76561 AI450660 sorting nexin 7 27393 21855 AI429549 translocator of inner mitochondrial membrane b electron transport 43415 12861 AI893442 cytochrome c oxidase, subunit VI a, polypeptide 1 0.234 14022 12868 AI326932 cytochrome c oxidase, subunit VIIIa 14781 13086 AI893559 cytochrome P450, family 2, subfamily a, polypeptide 4 21758 13106 AI323829 cytochrome P450, family 2, subfamily e, polypeptide 1 20115 13142 AI447515 D-amino acid oxidase 3533 56551 AI325495 thioredoxin 2 0.343 defense response 6417 12484 AI323855 CD24a antigen 22564 14969 AI447932 histocompatibility 2, class II antigen E beta 7043 16149 AI451110 Ia-associated invariant chain 41980 17086 AI450786 natural cytotoxicity triggering receptor 1 33874 142980 AI450647 toll-like receptor 3 154045 56753 AI426251 tumor-associated calcium signal transducer 2 heat shock response* 21549 80888 AI326838 Cryac Crystallin, alpha C 0.035 2982 81489 AI465465 Dnajb1 DnaJ (Hsp40) homolog, subfamily B, member 1 197601 15528 AI327085 Hspe1 Heat shock 10 kDa protein 1 (chaperonin 10) 22708 12406 AI326777 Serpinh1 Serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1 histogenesis and organogenesis 10663 17172 AI415258 achaete-scute complex homolog-like 1 (Drosophila) 0.49 27757 12153 AI327151 bone morphogenetic protein 1 215 15414 AI385768 homeo box B6 26544 15438 AI385671 homeo box D9 immune response 12895 20299 AI449147 chemokine (C-C motif) ligand 22 0.317 22564 14969 AI447932 histocompatibility 2, class II antigen E beta 18530 15950 AI661257 interferon activated gene 203 AI451137 1715 16994 AI327398 lymphotoxin B post-translational membrane targeting 6417 12484 AI323855 CD24a antigen 0.219 4911 12805 AI425965 contactin 1 1098 53872 AI323833 GPI-anchored membrane protein 1 1514 16956 AI326787 lipoprotein lipase sensory organ development* 22830 12957 AI325927 Cryba1 Crystallin, beta A1 0.035 86656 12958 AI324706 Cryba2 Crystallin, beta A2 30374 12966 AI323924 Crygc Crystallin, gamma C 20176 12964 AI323909 Mus musculus crystallin, gamma A (Cryga), mRNA small GTPase mediated signal transduction 196526 11845 AI449299 ADP-ribosylation factor 6 0.422 24443 14569 AI528719 guanosine diphosphate (GDP) dissociation inhibitor 3 734 18176 AI414879 neuroblastoma ras oncogene 757 11848 AI324087 ras homolog gene family, member A ubiquitin-dependent protein degradation 30097 26440 AI325451 proteasome (prosome, macropain) subunit, alpha type 1 0.445 368 19172 AI415623 proteasome (prosome, macropain) subunit, beta type 4 9002 22215 AI661496 ubiquitin protein ligase E3A 29352 22213 AI413443 ubiquitin-conjugating enzyme E2G 2 cation transport 80501 11982 AI327378 ATPase, Class V, type 10A 0.475 14926 11977 AI449437 ATPase, Cu++ transporting, alpha polypeptide 23020 16530 AI414909 potassium channel, subfamily K, member 7 cell cycle arrest 168789 12577 AI428384 cyclin-dependent kinase inhibitor 1C (P57) 0.167 7549 13198 AI323295 DNA-damage inducible transcript 3 3350 11426 AI449659 microtubule-actin crosslinking factor 1 DNA replication 29361 50793 AI427116 origin recognition complex, subunit 3-like (S. 0.422 cerevisiae) 9199 18974 AI451438 polymerase (DNA directed), epsilon 2 (p59 subunit) 12145 19646 AI324260 retinoblastoma binding protein 4 embryogenesis and morphogenesis 27757 12153 AI327151 bone morphogenetic protein 1 0.317 7320 17127 AI324173 MAD homolog 3 (Drosophila) 100399 17128 AI427147 MAD homolog 4 (Drosophila) mitosis 29133 12236 AI465548 budding uninhibited by benzimidazoles 1 homolog, beta 0.239 (S. cerevisiae) 118 12566 AI323666 cyclin-dependent kinase 2 8108 22390 AI465227 wee 1 homolog (S. pombe) proteolysis and peptidolysis* 27757 12153 AI327151 bone morphogenetic protein 1 0.018 28814 12368 AI326797 caspase 6 21306 17391 AI426335 matrix metalloproteinase 24 ribosome biogenesis 70127 19897 AI323900 hypothetical pseudogene ribosomal protein L12 0.056 5291 20103 AI464376 ribosomal protein S5 32033 20112 AI448582 ribosomal protein S6 kinase, polypeptide 2 synaptic transmission 32191 54393 AI449538 gamma-aminobutyric acid (GABA-B) receptor, 1 0.167 3292 14810 AI385669 glutamate receptor, ionotropic, NMDA1 (zeta 1) 23020 16530 AI414909 potassium channel, subfamily K, member 7 transcription regulation, from Pol II promoter 29275 56787 AI415295 achaete-scute complex homolog-like 3 (Drosophila) 0.105 3909 20585 AI327369 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 3 15781 22282 AI893650 upstream transcription factor 2 anti-apoptosis 692 11800 AI661160 apoptosis inhibitor 5 0.263 22216 14605 AI326808 glucocorticoid-induced leucine zipper carbohydrate metabolism 2040 12091 AI528555 galactosidase, beta 1 0.38 103675 50720 AI451106 ribonucleotide reductase M2 cell-matrix adhesion 1346 16401 AI450152 integrin alpha 4 0.171 757 11848 AI324087 ras homolog gene family, member A common-partner SMAD protein phosphorylation 7320 17127 AI324173 MAD homolog 3 (Drosophila) 0.093 100399 17128 AI427147 MAD homolog 4 (Drosophila) cytoskeleton organization and biogenesis 1000 17901 AI324023 myosin light chain, alkali, fast skeletal muscle 0.453 4010 22349 AI414231 villin DNA repair 28619 23894 AI327310 general transcription factor II H, polypeptide 2 0.453 12145 19646 AI324260 retinoblastoma binding protein 4 glycolysis 7729 11676 AI327146 aldolase 3, C isoform 0.171 29994 13808 AI325234 enolase 3, beta muscle hydrogen transport 20869 11975 AI451534 ATPase, H+ transporting lysosomal V0 subunit a isoform1 0.093 30155 11984 AI385732 ATPase, H+ transporting, V0 subunit C induction of apoptosis 28814 12368 AI326797 caspase 6 0.171 143798 58801 AI449135 phorbol-12-myristate-13-acetate-induced protein 1 integrin-mediated signaling pathway 1346 16401 AI450152 integrin alpha 4 0.359 757 11848 AI324087 ras homolog gene family, member A mRNA splicing 6787 20383 AI528616 splicing factor, arginine/serine-rich 3 (SRp20) 0.105 28150 81898 AI666563 splicing factor 3b, subunit 1 microtubule-based movement 29317 56444 AI326428 ARP10 actin-related protein 10 homolog (S. cerevisiae) 0.359 19726 13411 AI326265 dynein, axonemal, heavy chain 11 microtubule-based process 86654 17760 AI448037 microtubule-associated protein 6 0.077 1948 21648 AI465254 t-complex testis expressed 1 neurogenesis 10663 17172 AI415258 achaete-scute complex homolog-like 1 (Drosophila) 0.252 3507 18227 AI429298 nuclear receptor subfamily 4, group A, member 2 protein folding 28480 30795 AI427165 FK506 binding protein 3 0.38 197601 15528 AI327085 heat shock protein 1 (chaperonin 10) pattern specification 215 15414 AI385768 homeo box B6 0.093 26544 15438 AI385671 homeo box D9 potassium transport 424 11933 AI450702 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.459 23020 16530 AI414909 potassium channel, subfamily K, member 7 protein kinase cascade* 202311 14674 AI426467 guanine nucleotide binding protein, alpha 13 0.035 29857 64011 AI326818 neurogranin protein modification 20874 18602 AI666339 peptidyl arginine deiminase, type IV 0.359 9002 22215 AI661496 ubiquitin protein ligase E3A RHO protein signal transduction 202311 14674 AI426467 guanine nucleotide binding protein, alpha 13 0.093 757 11848 AI324087 ras homolog gene family, member A RNA processing 16767 53379 AI449004 heterogeneous nuclear ribonucleoprotein A2/B1 0.263 111 18521 AI893657 poly(rC) binding protein 2 actin cytoskeleton organization and biogenesis 3529 12343 AI528740 capping protein (actin filament) muscle Z-line, alpha 2 0.288 action potential regulation 989 14672 AI528620 guanine nucleotide binding protein, alpha 11 0.05 amino acid biosynthesis* 29751 56454 AI324071 pyrroline-5-carboxylate synthetase (glutamate 0.035 gamma-semialdehyde synthetase) angiogenesis 202311 14674 AI426467 guanine nucleotide binding protein, alpha 13 0.05 anion transport 569 22334 AI430965 voltage-dependent anion channel 2 0.05 ATP biosynthesis 30155 11984 AI385732 ATPase, H+ transporting, V0 subunit C 0.288 base conversion/substitution editing 153899 56417 AI449308 adenosine deaminase, RNA-specific 0.05 biosynthesis 27419 69606 AI450131 RIKEN cDNA 2310020P08 gene 0.288 cell communication 26859 14622 AI323309 gap junction membrane channel protein beta 5 0.159 cell differentiation 202311 14674 AI426467 guanine nucleotide binding protein, alpha 13 0.159 cell growth 18213 21808 AI323791 transforming growth factor, beta 2 0.05 cell proliferation 4078 17345 AI428398 antigen identified by monoclonal antibody Ki 67 0.47 cell shape control 202311 14674 AI426467 guanine nucleotide binding protein, alpha 13 0.159 cell-cell signaling 26859 14622 AI323309 gap junction membrane channel protein beta 5 0.288 cellular defense response 30557 21473 AI449302 T-cell receptor alpha chain 0.288 central nervous system development 9524 17684 AI430768 Cbp/p300-interacting transactivator, with Glu/Asp-rich 0.05 carboxy-terminal domain, 2 chemotaxis 12895 20299 AI449147 chemokine (C-C motif) ligand 22 0.47 cholesterol metabolism 28099 20652 AI385523 sterol O-acyltransferase 1 0.05 chromatin assembly/disassembly 28003 12419 AI893653 chromobox homolog 5 (Drosophila HP1a) 0.288 chromatin modeling 29546 56456 AI447773 BRG1/brm-associated factor 53A 0.05 chromosome organization and biogenesis (sensu Eukarya) 193557 15269 AI323498 similar to germinal histone H4 gene 0.47 copper ion transport 14926 11977 AI449437 ATPase, Cu++ transporting, alpha polypeptide 0.05 cytokine and chemokine mediated signaling pathway 103809 58184 AI414253 rcd1 (required for cell differentiation) homolog 1 0.159 (S. pombe) detoxification response 4316 11863 AI451564 aryl hydrocarbon receptor nuclear translocator 0.05 developmental processes 4524 16825 AI465231 LIM domain binding 1 0.224 DNA dependent DNA replication 214703 117599 AI451189 helicase (DNA) B 0.05 DNA methylation 322 17191 AI449099 methyl-CpG binding domain protein 2 0.288 DNA modification 20915 21976 AI428343 topoisomerase (DNA) III beta 0.05 DNA packaging 2756 15312 AI426113 similar to nonhistone chromosomal protein HMG-14 - 0.415 mouse DNA replication, priming 214703 117599 AI451189 helicase (DNA) B 0.159 DNA topological change 20915 21976 AI428343 topoisomerase (DNA) III beta 0.05 DNA unwinding 20915 21976 AI428343 topoisomerase (DNA) III beta 0.05 dopamine receptor signaling pathway 20964 14681 AI661491 guanine nucleotide binding protein, alpha o 0.05 endoderm development 1424 14042 AI385657 exostoses (multiple) 1 0.05 fatty acid metabolism 6611 26458 AI326155 solute carrier family 27 (fatty acid transporter), 0.47 member 2 galactose metabolism 2820 14635 AI894127 galactokinase 1 0.05 gastrulation 1424 14042 AI385657 exostoses (multiple) 1 0.05 glutamate signaling pathway 989 14672 AI528620 guanine nucleotide binding protein, alpha 11 0.05 glutathione biosynthesis 4559 14598 AI323672 gamma-glutamyltransferase 1 0.05 glutathione metabolism 4559 14598 AI323672 gamma-glutamyltransferase 1 0.05 G-protein signaling, adenylate cyclase activating pathway 153916 11540 AI465291 adenosine A2a receptor 0.159 heart development 989 14672 AI528620 guanine nucleotide binding protein, alpha 11 0.05 heavy metal ion transport 14926 11977 AI449437 ATPase, Cu++ transporting, alpha polypeptide 0.159 heparan sulfate proteoglycan metabolism 103788 27029 AI464451 calbindin 1, 28 kDa 0.05 humoral immune response 138544 16121 AI450390 immunoglobulin kappa chain variable 4 (V4) 0.415 inflammatory response 12895 20299 AI449147 chemokine (C-C motif) ligand 22 0.288 ion transport 3292 14810 AI385669 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.202 ionic insulation of neurons by glial cells 1268 18823 AI323793 proteolipid protein 1 (Pelizaeus-Merzbacher disease, 0.05 spastic paraplegia 2, uncomplicated) iron homeostasis 7500 14325 AI449517 ferritin light chain 1 0.159 iron transport 7500 14325 AI449517 ferritin light chain 1 0.159 JAK-STAT cascade 38869 56469 AI448242 protein inhibitor of activated STAT 1 0.05 lipid catabolism 1514 16956 AI326787 lipoprotein lipase 0.47 lipid metabolism 1514 16956 AI326787 lipoprotein lipase 0.415 lipid transport 1514 16956 AI326787 lipoprotein lipase 0.288 locomotory behavior 20964 14681 AI661491 guanine nucleotide binding protein, alpha o 0.159 lymph gland development 1715 16994 AI327398 lymphotoxin B 0.415 lysosomal lumen acidification 30155 11984 AI385732 ATPase, H+ transporting, V0 subunit C 0.05 melanin biosynthesis, from tyrosine 19987 13190 AI325230 ATPase, Cu++ transporting, alpha polypeptide 0.05 mercury ion transport 14926 11977 AI449437 ATPase, Cu++ transporting, alpha polypeptide 0.05 mesoderm development 1424 14042 AI385657 exostoses (multiple) 1 0.05 metabotropic glutamate receptor signaling pathway 10022 26558 AI327089 homer homolog 3 (Drosophila) 0.159 mitotic cycle control 18994 56321 AI426755 apoptosis antagonizing transcription factor 0.05 mRNA processing 28150 81898 AI666563 splicing factor 3b, subunit 1 0.159 mRNA splice site selection 6787 20383 AI528616 splicing factor, arginine/serine-rich 3 (SRp20) 0.415 muscle contraction regulation 35134 11937 AI324248 ATPase, Ca++ transporting, cardiac muscle, fast twitch1 0.288 muscle development 1000 17901 AI324023 myosin light chain, alkali, fast skeletal muscle 0.415 neuroblast determination 10663 17172 AI415258 achaete-scute complex homolog-like 1 (Drosophila) 0.05 nitrogen fixation 2338 14645 AI413315 glutamate-ammonia ligase (glutamine synthase) 0.159 nucleosome assembly 193557 15269 AI323498 similar to germinal histone H4 gene 0.288 one-carbon compound metabolism 3379 20425 AI452103 serine hydroxymethyl transferase 1 (soluble) 0.05 ossification 27757 12153 AI327151 bone morphogenetic protein 1 0.05 oxygen transport* 30266 15129 AI323916 Hbb-b1 hemoglobin, beta adult major chain 0.023 peptide hormone processing 4881 30052 AI604765 proprotein convertase subtilisin/kexin type 1 inhibitor 0.05 peptide metabolism* 5121 18484 AI323455 peptidylglycine alpha-amidating monooxygenase 0.035 peroxisome organization and biogenesis 20901 18632 AI596335 peroxisomal biogenesis factor 11b 0.47 phototransduction 12925 18582 AI414297 phosphodiesterase 6D, cGMP-specific, rod, delta 0.159 proline biosynthesis 29751 56454 AI324071 pyrroline-5-carboxylate synthetase (glutamate 0.05 gamma-semialdehyde synthetase) protein amino acid ADP-ribosylation 2816 11875 AI323430 ADP-ribosyltransferase 5 0.159 protein amino acid dephosphorylation 20253 54384 AI327236 myotubularin related protein 7 0.055 protein amino acid glycosylation 10701 20452 AI385627 sialyltransferase 8 (alpha-2, 8-sialyltransferase) D 0.159 protein metabolism and modification 22271 80886 AI596338 similar to smt3-specific isopeptidase 1; 0.159 sentrin/SUMO-specific protease protein secretion 28375 53421 AI327023 SEC61, alpha subunit (S. cerevisiae) 0.288 protein transport 27393 21855 AI429549 translocator of inner mitochondrial membrane b 0.371 protein-nucleus import, docking 16710 16211 AI323858 karyopherin (importin) beta 1 0.159 purine nucleoside transport 29510 59023 AI413193 solute carrier family 28 (sodium-coupled nucleoside 0.05 transporter), member 2 RAS protein signal transduction 734 18176 AI414879 neuroblastoma ras oncogene 0.371 receptor mediated endocytosis 2735 65969 AI661835 SWI/SNF related, matrix associated, actin dependent 0.05 regulator of chromatin, subfamily d, member 1 regulation of body size 4132 12701 AI464459 suppressor of cytokine signaling 2 0.159 regulation of cell migration 2453 20604 AI326805 somatostatin 0.05 retinoid metabolism 2450 19659 AI893623 retinol binding protein 1, cellular 0.05 rhythmic behavior 10723 18628 AI428816 period homolog 3 (Drosophila) 0.05 skeletal development 989 14672 AI528620 guanine nucleotide binding protein, alpha 11 0.05 SMAD protein heteromerization 7320 17127 AI324173 MAD homolog 3 (Drosophila) 0.159 SMAD protein nuclear translocation* 100399 17128 AI427147 MAD homolog 4 (Drosophila) 0.05 sodium transport 424 11933 AI450702 ATPase, Na+/K+ transporting, beta 3 polypeptide 0.288 spermatogenesis 4559 14598 AI323672 gamma-glutamyltransferase 1 0.371 steroid biosynthesis 28099 20652 AI385523 sterol O-acyltransferase 1 0.159 steroid metabolism 5129 20905 AI430879 steroid sulfatase 0.05 transcription 27375 17749 AI661386 metallothionein-I activator 0.159 transmembrane receptor protein tyrosine kinase signaling pathway 8534 13649 AI427644 epidermal growth factor receptor 0.415 ubiquitin cycle 9002 22215 AI661496 ubiquitin protein ligase E3A 0.415 vacuolar acidification 30155 11984 AI385732 ATPase, H+ transporting, V0 subunit C 0.05 very long chain fatty acid metabolism 2567 54326 AI448451 elongation of very long chain fatty acids (FEN1/Elo2, 0.05 SUR4/Elo3, yeast)-like 2 water transport 40333 11831 AI452338 aquaporin 6 0.159 Wnt receptor signaling pathway 7883 11789 AI451571 adenomatosis polyposis coli 0.05 xenobiotic metabolism 22637 64296 AI661482 RIKEN cDNA 0910001L24 gene 0.05 |