Figure 3 of
Hagan, Mol Vis 2003;
Figure 3. Effects of SPARC on HRPE cell-mediated contraction of collagen matrices
The histogram illustrates the effects of SPARC on HRPE cell-mediated contraction of collagen matrices over a 7 day period (a 2D model of PVR). Test media constituents were as noted in figure. At 4 days (black bars), post-seeding matrix contraction was significantly diminished by 1 and 10μg/ml SPARC (*p<0.01). However, by 7 days (gray bars), there was no significant difference in matrix contraction between SPARC-exposed cells and positive controls. Error bars represent the standard error of the mean.