Figure 3 of
Armstrong, Mol Vis 2003;
**9**:74-79.

Figure 3. The effect of thrombospondin antibodies on keratocyte-mediated matrix contraction

**A**: Histograms showing the mean matrix area (error bars
represent the standard deviation) for human corneal keratocyte-seeded
(3D) collagen matrices in the presence or absence of antibodies directed
against TSP-2 and TSP-3 (both antibodies at final concentration of 20
μg/ml). At days 1, 3, and 7 there were significant differences (p<0.01; n=9-11) between the TSP-2 antibody treated group and the untreated
control group (20 μg/ml goat IgG). There was no significant
difference between the control group and TSP 3 antibody treated
matrices. **B**: Histograms showing the mean matrix area (error bars
represent the standard deviation) for human corneal keratocyte-seeded
(3D) collagen matrices in the presence or absence of antibodies directed
against TSP-2 (antibodies at final concentration of 20 μg/ml and 2
μg/ml). At days 1, 3, and 7 there were significant differences (p<0.01; n=9-11) between the TSP-2 20 μg/ml antibody treated group and
the untreated control group (20 μg/ml goat IgG). At days 1 and 3
there were significant differences (p<0.01; n=9-11) between the
TSP-2, 2 μg/ml antibody treated group and the untreated control group
(2 μg/ml goat IgG). On day 7 there was no significant difference
between the control group (2 μg/ml goat IgG) and the TSP-2, 2 μg/ml antibody treated group.

Armstrong, Mol Vis 2003;

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