Table 1 of
Vickers, Mol Vis 2002;
8:389-393.Table 1 of
Vickers, Mol Vis 2002;
8:389-393.
Table 1. Apolipoprotein E genotype and allelic frequencies
Distribution of genotypes and allelic frequencies in normal tension glaucoma, high tension glaucoma, and cases lacking glaucoma (controls). For each row of the table, differences in proportions between cases and controls were assessed using Fisher's exact test. Asterisks ("*") indicate significant differences (α=0.05 for each test).
Control Normal tension High tension
Genotype (n=51) glaucoma (n=70) glaucoma (n=72)
--------- ---------- --------------- ---------------
ε2/ε2 2 (3.9%) 5 (7.1%) 1 (1.4%)
ε2/ε3 9 (17.7%) 5 (7.1%) 3 (4.7%)*
ε3/ε3 30 (58.8%) 33 (47.1%) 45 (62.5%)
ε3/ε4 6 (11.8%) 21 (30.0%)* 21 (29.2%)*
ε2/ε4 2 (3.9%) 5 (7.1%) 2 (2.8%)
ε4/ε4 2 (3.9%) 1 (1.4%) 0 (0.0%)
Allele Control Normal tension High tension
frequency (n=51) glaucoma (n=70) glaucoma (n=72)
--------- ---------- --------------- ---------------
ε2 15 (14.7%) 20 (14.3%) 7 (4.9%)*
ε3 75 (73.5%) 92 (65.7%) 114 (79.2%)
ε4 12 (11.8%) 28 (20.0%) 23 (16.0%)
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