Figure 11. Distribution of candidate FGF-related signaling molecules in human retina ex vivo

Human retinal sections taken from the central posterior region within 5 mm of the papilla (shown by differential interference contrast microscopy in A) were immunolabeled with antibodies specific for PLCg1 (B), SOS1 (C), SOS2 (D), ERK1/2 (F), SH-PTP2 (G), and Shc (H). E: Representative control section in which the primary antibody (in this case ERK1/2) was pre-adsorbed with the corresponding immunizing peptide prior to labeling. Explanations of labeling patterns are given in the text. Abbreviations used: GCL, ganglion cell layer; INL, inner nuclear layer; IPL, inner plexiform layer; IS, photoreceptor inner segments; ONL, outer nuclear layer; OPL, outer plexiform layer; OS, photoreceptor outer segments. Magnification x200.