Table 2 of Dekomien, Mol Vis 2002; 8:138-142.


Table 2. Characteristics of investigated dogs

Characteristics included age of onset forms, age distribution of normal and gPRA affected dogs during the time of DNA isolation, and allele frequencies of the PDC gene in the different breeds examined. The ages of onset in the different breeds were classified according to [31] for AC; according to the owners' report/certificate of eye examination for BDP, Bo, D, GR, IRS (late form) NF, PON, Ro, Sa, ScT, SD, Sl and TM; according to reviews [1,32] and online information from PRA Today for Co, ECS, IRS (early form) LR, MP and TT; and according to [33] for EM. For abbreviations see Table 1.

                                                         Allele frequency (%)
                                                     ----------------------------
                                          Age         IVS3    IVS3 -63   IVS3 -64
                        Onset forms   distribution   16-18      T->A       A->T
Breed     Diagnosis       of gPRA        (year)      delTCT      A          T
-----   -------------   -----------   ------------   ------   --------   --------

AC      gPRA-affected      late            10          -         -          -
        normal                            2-4          -         -          -
BDP     gPRA-affected    mid-onset         5           -         -          -
        normal                            1-10         17        17         -
Bo      gPRA-affected      late            9           -         -          -
Co      gPRA-affected      early          4-8          -         25         -
        normal                             8           -         50         -
D       gPRA-affected    variable         1-13         28        20         -
        normal                            6-13         50        37         -
ECS     gPRA-affected      late           3-11         50        60         -
        normal                            6-14         -         -          -
EM      gPRA-affected      late           5-13         -         -          59
        normal                            1-7          -         -          29
GR      gPRA-affected      late           5-10         -         25         -
        normal                            3-6          -         12         -
IRS     gPRA-affected   early/late        0,6-7        50        25         -
        normal                            3-13         -         -          -
LR      gPRA-affected      late           8-12         -         -          -
        normal                            3-13         14        2          -
MP      gPRA-affected      late           5-12         29        17         -
        normal                            1-12         20        30         -
NF      gPRA-affected    mid-onset         3           -         -          -
PON     gPRA-affected      late            9           -         -          -
Ro      gPRA-affected      late            3           -         -          -
Sa      gPRA-affected      late           7-9          -         -          19
        normal                            2-10         -         -          27
ScT     gPRA-affected      late            6           -         -          -
SD      gPRA-affected      early          2-6          -         -          -
        normal                            3-6          -         -          -
Sl      gPRA-affected    mid-onset         2           50        25         -
        normal                           0,1-12        38        56         -
TM      gPRA-affected    mid-onset         4           -         50         -
        normal                             4           50        -          -
TT      gPRA-affected    mid-onset        7-8          34        17         -
        normal                            2-10         11        21         -

Dekomien, Mol Vis 2002; 8:138-142 <http://www.molvis.org/molvis/v8/a19/>
©2002 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535