Figure 2. Chromatograms of the polymorphisms in the PDC gene

Partial chromatograms demonstrating the polymorphisms in intron 3 of the PDC gene. A: The sequence of a Dachshund is shown including the wild type sequence from position -70 to -48 as well as positions -26 to -5 evidencing the deletion (up arrow) from -18 to -16. B: Respective selected portions of the PDC gene from an Entlebucher Sennenhund are depicted including the substitution in position -64. Since this individual dog is heterozygous for the substitution, a mixed chromatography signal (N) is readily explained.