Table 2. Rhodopsin concentration per eye

Data were combined from trkB^-/- [8] and trkB^fbz/fbz mice (data reported here). It should be noted that the absolute amounts of rhodopsin (middle column) differ between the two sets of experiments due to the different methods and instruments used. Data was again normalized to their respective wild type (WT) controls to allow comparison of the different genotypes. Again, a 75% or greater loss of trkB (trkB^fbz/fbz and trkB^-/-) resulted in a dose dependent decrease in retinal rhodopsin, which was reflected in the electroretinogram data analysis. Abbreviations: P16: postnatal day 16; P20: postnatal day 20. p values: *p<0.04; **p<0.003.

                 Rhodopsin Concentration
   Genotype          [nmole per eye]       Percent of Genotype WT
--------------   -----------------------   ----------------------

 P16 WT             0.1720 ± 0.0150            100    ±  8.72
 P20 WT             0.0977 ± 0.0177            100    ± 18.12
 trkB(fbz/+)        0.0764 ± 0.0135             78.20 ± 13.82
 trkB(fbz/fbz)      0.0425 ± 0.0123*            43.5  ± 12.59
 trkB(-/-)          0.0563 ± 0.0050**           32.73 ±  2.91