Table 1 of
Rohrer, Mol Vis 2001;
7:288-296.Table 1 of
Rohrer, Mol Vis 2001;
7:288-296.
Table 1. Characteristics of a- and b-waves
Data was combined from the two sets of animals, normalized to their respective wild type (WT) controls and expressed in [% WT levels]. The retina appears to be able to compensate for a loss of up to 50% of trkB (trkB+/fbz and trkB+/-) with respect to amplitudes, light sensitivity and kinetics; whereas any further loss (trkBfbz/fbz and trkB-/-) resulted in a dose dependent deterioration of sensitivity and kinetics. p values: *p<0.01; **p<0.003; #p<0.05; ##p<0.005.
a-wave a-wave b-wave b-wave
Genotype Amplitude Slope Amplitude Slope
------------- ------------- -------------- -------------- ---------------
WT 100.0 ± 25.4 100.0 ± 8.1 100.0 ± 41.0 100.0 ± 41.2
trkB(+/fbz) 104.4 ± 9.6 101.6 ± 13.5 122.9 ± 17.7 111.39 ± 39.6
trkB(+/-) 105.6 ± 17.0 (not done) 93.3 ± 24.5 (not done)
trkB(fbz/fbz) 74.8 ± 12.2* 75.8 ± 25.3 53.8 ± 35.9## 38.2 ± 23.2**
trkB(-/-) 25.4 ± 12.1# 52.4 ± 22.0## 0 ± 0 0 ± 0
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