Figure 1. Expression of cytokeratin

A: Corn1 mice expressed keratin 12 throughout the normal areas of corneal epithelium. B: Corn1 mice expressed keratin 12 throughout the entire epithelial layer, but most prominently in the lower half of areas of hyperplasia and rough superficial cells. C: Wild type mice expressed keratin 12 throughout the corneal epithelium. D: Corn1 mice expressed keratin 14 in the basal cells of corneal epithelium. E: Corn1 mice expressed keratin 14 in hyperplastic corneal epithelium, especially in the basal and suprabasal cells. F: Expression of keratin 14 in the basal layer of corneal epithelium in wild type mice. G, H, and I: Anti-keratin 1 antibodies were not expressed in the corn1 and wild type mice. J, K, and L: Antibodies directed against keratin 4 were negative in both corn1 and wild type mice.